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Developing core outcome sets for clinical trials needs patient input

January 25th, 2011

In this week's PLoS Medicine, Ian Sinha and colleagues from the Institute of Child Health, University of Liverpool, UK, make recommendations for the development of core outcome sets for clinical trials, based upon a review of the literature. They advise that when using the Delphi process to develop core outcome sets for clinical trials, patients and clinicians should be involved, researchers and facilitators should avoid imposing their views on participants, and the attrition of participants must be minimized.

Citation: Sinha IP, Smyth RL, Williamson PR (2011) Using the Delphi Technique to Determine Which Outcomes to Measure in Clinical Trials: Recommendations for the Future Based on a Systematic Review of Existing Studies. PLoS Med 8(1): e1000393. doi:10.1371/journal.pmed.1000393

www.plosmedicine.org/article/info%3Adoi%2F10.1371%2Fjournal.pmed.1000393

Provided by Public Library of Science

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