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Medical Xpress / Human sperm mutations that can cause disease in children identified

Throughout development, life and the processes of aging, all human cells accumulate mutations, resulting in what is called mosaicism, a condition in which different cells in the same person have different DNA sequences or ...

Aug 13, 2021 in Genetics
Medical Xpress / Researchers find vital enzyme holds key to the fight against cancer and viral infections

A new study led by University of California, Irvine (UCI) researchers identifies two ways in which APOBEC3A— a vital enzyme that is responsible for genetic changes resulting in a variety of cancers while protecting our ...

Aug 13, 2021 in Medical research
Medical Xpress / Brain cholesterol regulates Alzheimer's plaques, study reveals

A team co-led by scientists at Scripps Research has used advanced imaging methods to reveal how the production of the Alzheimer's-associated protein amyloid beta (Aβ) in the brain is tightly regulated by cholesterol.

Medical Xpress / Immunocompromised dialysis patients could benefit from third doses of mRNA COVID-19 vaccine

Patients receiving in-hospital dialysis treatment for kidney disease produce a larger neutralizing antibody response when given the Pfizer-BioNTech COVID-19 vaccine, compared to the Oxford-AstraZeneca vaccine, according to ...

Aug 13, 2021 in Vaccination
Medical Xpress / Moderna COVID-19 vaccine found to be still effective after six months

A team of researchers at the U.S. National Institutes of Health, working with colleagues from Emory University School of Medicine, Emmes Company, Moderna, Inc. and Kaiser Permanente Washington Health Research Institute, has ...

Aug 13, 2021 in Medical research
Medical Xpress / New tumor cell tracking system aims to understand cancer treatment resistance

Despite tremendous advances in medicine, tumors are challenging to cure because they are made up of heterogeneous cells. In other words, like human families, the individual cells of a tumor share some common traits and characteristics, ...

Aug 13, 2021 in Oncology & Cancer
Medical Xpress / Shared antibodies may push COVID variants: study

Researchers at Vanderbilt University Medical Center have found that people recovering from COVID-19 and those vaccinated against the causative virus, SARS-CoV-2, produce identical clones, or groups, of antibody-producing ...

Medical Xpress / Better reporting, measurement and control of the environmental conditions of cell cultures is needed

There is an urgent need for the reporting of biomedical research on mammalian cells to be more standardized and detailed, and greater control over and measurement of the environmental conditions of cell cultures need to be ...

Aug 13, 2021 in Medical research
Medical Xpress / Making the case for plant-based vaccines

A pair of researchers at Université Laval, Quebec claim that more effort should be made to develop plant-based vaccines. Hugues Fausther-Bovendo and Gary Kobinger have published a Perspective piece in the journal Science ...

Aug 13, 2021 in Medical research
Medical Xpress / Researchers unlock genetic 'treasure map' for chronic kidney disease

Despite impacting an estimated 850 million people and being responsible for 1 in 60 deaths worldwide, few treatments are available for chronic kidney disease. Understanding the genetic variations associated with the disease ...

Aug 13, 2021 in Genetics
Medical Xpress / Disease ecologists document person-to-person spread of antimicrobial-resistant plague

Although the world is focused on the COVID-19 pandemic, there are many other dangerous pathogens still out there, like Yersinia pestis, which causes plague—the deadly disease that killed tens of millions of people during ...

Medical Xpress / Lung drug hope for heart failure patients

An early phase trial of a drug currently used to treat lung fibrosis has shown it may also help patients who suffer from a common form of heart failure.

Aug 13, 2021 in Medical research