Medical Xpress news

Medical Xpress / Protein 'seeds' trigger key pathological features of ALS and frontotemporal dementia
Accumulation of a protein called TDP-43 is a key feature of ALS and frontotemporal dementia. In a study published in Neuron, researchers report 'seeding' this accumulation through fragments of the culprit protein created ...

Medical Xpress / Intermittent fasting increases sex drive in male mice: An approach for low libido in humans?
Long-term fasting in 24-hour cycles increases the sex drive of male mice by lowering the concentration of the neurotransmitter serotonin in the brain. This effect is linked to a diet-induced deficiency of the precursor substance ...

Medical Xpress / Songbirds highlight dopamine's role in learning
Many everyday skills, such as speech, are not innate. They are learned through trial and error. Now, by analyzing young songbirds rehearsing their fathers' songs, researchers at Columbia's Zuckerman Institute have for the ...

Medical Xpress / Duchenne muscular dystrophy's impact on the brain may be reversible
New research led by the University of Portsmouth has revealed how Duchenne muscular dystrophy (DMD), best known for causing severe muscle degeneration, also profoundly affects the brain, leading to cognitive and behavioral ...

Medical Xpress / Supercomputer uncovers immune system's secret to self-tolerance
A discovery published in Nature Immunology has shed light on why the immune system is less aggressive toward self-antigens, offering new opportunities to enhance cancer immunotherapy.

Medical Xpress / Surgery may not be necessary to treat invasive breast cancer
Surgery may not be the best next course of treatment for patients with early-stage breast cancer who had a complete response to neoadjuvant (pre-surgical) chemotherapy and standard radiation treatment, according to new data ...

Medical Xpress / Fatty acids promote immune suppression and therapy resistance in triple negative breast cancer, study shows
A new study published in the journal Immunity reveals a mechanism that allows triple negative breast cancer (TNBC) to develop resistance to therapy.

Medical Xpress / PET imaging confirms direct involvement of dopamine in cognitive flexibility
For the first time, scientists have confirmed a neurobiochemical link between dopamine and cognitive flexibility, according to new research published in the March issue of The Journal of Nuclear Medicine. PET imaging shows ...

Medical Xpress / Scientists uncover how TBK1 and IKKε prevent premature cell death and inflammation
New research from the Kennedy Institute has revealed how two important proteins, TBK1 and IKKε, play a crucial role in preventing premature cell death, which can lead to serious inflammation in the body. The findings are ...

Medical Xpress / Understanding the immune response to Toxoplasma gondii, a persistent pathogen
Most humans have long-lived infections in various tissues—including in the nervous system—that typically do not result in disease. The microbes associated with these infections enter a latent stage during which they quietly ...

Medical Xpress / AI meets oncology: New model personalizes bladder cancer treatment
Leveraging the power of AI and machine learning technologies, researchers at Weill Cornell Medicine developed a more effective model for predicting how patients with muscle-invasive bladder cancer will respond to chemotherapy. ...

Medical Xpress / Gender-affirming care may reduce the risk of HIV among trans, nonbinary and gender-diverse people
Gender-affirming hormone therapy (GAHT) is associated with significantly improved HIV outcomes for transgender, nonbinary, and other gender-diverse (trans) people in the U.S., according to a new study published in The Lancet ...