Medical Xpress news
Medical Xpress / Working memory may rely on calcium-tuned synaptic boosts, study suggests
Working memory is a cognitive function that is essential for carrying out everyday activities and temporarily retaining information. This process enables us to understand information, learn and manage responses in a controlled ...
Medical Xpress / How serotonin can be hijacked in the brain
Scientists have uncovered a powerful strategy that the brain uses to coordinate chemical signaling. In a new study, researchers found that in the striatum, a brain region central to learning and moving, one chemical signaling ...
Medical Xpress / Largest-ever Parkinson's study shows how symptoms differ between men and women
Parkinson's disease is the fastest growing neurological disorder, with more than 10 million cases worldwide. Up to 150,000 Australians currently live with the disease and 50 new cases are diagnosed each day.
Medical Xpress / Modeling suggests climate change could drive millions into physical inactivity by 2050
Rising temperatures due to climate change could drive millions more adults globally into physical inactivity by 2050, being linked to hundreds of thousands of premature deaths and billions of dollars in lost productivity, ...
Medical Xpress / Brain computer interface enables rapid communication for two people with paralysis
Loss of communication can be among the most devastating symptoms for patients with paralysis. A new study by investigators from Mass General Brigham Neuroscience Institute and Brown University describes an investigational ...
Medical Xpress / Gene expression program linked to neurotransmission in the living human brain identified
Researchers have identified a distinct and reproducible gene expression program associated with neurotransmission in the living human brain, offering unprecedented insight into the molecular mechanisms that support human ...
Medical Xpress / A poorly 'cleaned' brain may increase the risk of psychosis
How can the onset of psychotic symptoms characteristic of schizophrenia be explained? Despite their major and often irreversible impact on intellectual abilities and autonomy, the biological mechanisms that precede their ...
Medical Xpress / Experimental oral therapy PrimeC shows safety and signals of clinical benefit in ALS
In a phase 2b clinical trial, an investigational oral therapy called PrimeC was found to be safe and well tolerated in people living with amyotrophic lateral sclerosis (ALS), with exploratory findings suggesting target engagement ...
Medical Xpress / Mapping mental health to deal with the messy reality of psychiatric diagnoses
Depression or ADHD? Neatly delineated diagnoses fail to do justice to the infinitely complex reality that they refer to, argues Eiko Fried in a new paper for JAMA Psychiatry. His proposal: to map the underlying mechanisms ...
Medical Xpress / How a rare pediatric liver cancer emerges
Liver cancer in children is rare, but when it occurs, the two main types are hepatoblastoma (HB) and hepatocellular carcinoma (HCC). In some cases, however, the tumors show features of both types. These tumors have been classified ...
Medical Xpress / New genetic risk score better predicts diabetes, obesity and downstream complications
Type 2 diabetes (T2D) and obesity are metabolic conditions with many causes, including overlapping and distinct genetic features. A polygenic risk score (PRS) can capture multiple genetic risk factors to provide an estimate ...
Medical Xpress / Twice‑yearly injectable HIV regimen treatment demonstrates strong efficacy and safety in Phase 2 trial
A new study published in The Lancet Microbe reports the first twice-yearly injectable HIV treatment regimen—combining lenacapavir, teropavimab, and zinlirvimab—has achieved high rates of viral suppression and demonstrated ...