Medical Xpress news
Medical Xpress / 'Toxic' molecule may play vital role in gene regulation and development
A molecule once thought to be a harmful metabolic byproduct may play a crucial role in early development and gene regulation, according to a new study published in Nature that challenges decades of biochemical assumptions. ...
Medical Xpress / Lab-grown heart patch boosts pumping power in severe heart failure trial
Researchers at the University Medical Center Göttingen (UMG) and the University Hospital of Schleswig-Holstein (UKSH) have made a significant breakthrough in the treatment of severe heart failure: For the first time, a clinical ...
Medical Xpress / Immune 'energy signature' linked to tuberculosis may explain why some individuals control infection
Researchers at Trinity College Dublin have identified key differences in how immune cells generate and use energy, a process known as cellular metabolism, in people with latent versus active tuberculosis (TB). The findings ...
Medical Xpress / Brain maps reveal first lifetime white matter growth charts from birth to 100
In a new study published recently in the journal Nature, researchers at Vanderbilt University and Vanderbilt Health have created the first growth charts for white matter in the brain over a human lifetime. The work brings ...
Medical Xpress / Do lying children grow up to be criminals? Mostly not, but persistent patterns may signal later risk
Most childhood lying does not lead to serious problems in adulthood, and only certain kinds of lying behavior are associated with later psychological or legal issues, a new study has found.
Medical Xpress / Psychiatric 'gold standard' falters as repeat interviews yield different diagnoses
Diagnostic interviews are widely used by mental health professionals to identify conditions such as anxiety, bipolar disorder and depression in adults, but new research led by McMaster University shows that the long considered ...
Medical Xpress / Depression may not only be a consequence, but also a cause of rheumatoid arthritis
According to researchers at Semmelweis University, not only inflammation, but also sleep disorders, depression, obesity, and smoking may sustain persistent rheumatic symptoms. In their publications in the journals Nature ...
Medical Xpress / Ocrelizumab cuts disability progression in primary progressive MS trial
A major international Phase III clinical trial, led by Queen Mary University of London, has found that ocrelizumab—a medication already prescribed to some patients with MS—significantly slows disability progression in people ...
Medical Xpress / AI-powered atlas reveals new insights into tertiary lymphoid structures as prognostic and response biomarkers in cancer
In a study published in Science, researchers from The University of Texas MD Anderson Cancer Center have developed a spatial atlas of specialized immune structures, called tertiary lymphoid structures (TLSs), across multiple ...
Medical Xpress / Scientists identify metabolic target to overcome chemotherapy resistance in ovarian cancer
Many cancers can be treated by administering DNA-damaging agents, such as platinum-based chemotherapy, because the resulting DNA damage causes the cancer cells to die. A subset of cancers, however, including ovarian cancers, ...
Medical Xpress / Brain aging reveals rising transposon RNAs, with distinct shifts in Huntington's and Parkinson's
Transposable elements (TEs), also called transposons, are DNA sequences capable of moving or replicating from one location to another within a genome. While TEs are the most significant fraction of the human genome (approximately ...
Medical Xpress / Gene activity clocks estimate lifespan across species, matching epigenetic tools
Molecular clocks that can provide accurate estimates of both molecular age and lifespan across multiple mammalian species and tissue types are presented in an article published in Nature this week. An analysis of more than ...