Medical Xpress news
Medical Xpress / Extra SORLA protein shields brain connections from tau tangles in mouse models
Alzheimer's disease and many other forms of neurodegeneration share a common culprit. In these diseases, tau proteins that normally stabilize neuronal microtubule filaments within our nervous system networks instead form ...
Medical Xpress / Which genes make people more susceptible to depression and other psychiatric disorders?
A study by the University of Barcelona has identified nearly 20 genes that could contribute to some people being more susceptible to depression, anxiety and traits such as irritability and neuroticism. These genes are regulated ...
Medical Xpress / Early warning signs of potential drug resistance in schistosomiasis parasite revealed
Scientists have identified genetic changes in wild populations of the parasitic worm that causes schistosomiasis that may reduce its response to praziquantel, the only available treatment. The study provides an early warning ...
Medical Xpress / Researchers uncover novel pathway that causes epilepsy
Researchers have uncovered a novel biological pathway that can lead to seizures when disrupted. The findings also provide a new approach to improve the diagnosis of epilepsy, for which a genetic cause cannot be found in about ...
Medical Xpress / LIG1 loss exposes a therapeutic vulnerability in triple-negative breast cancer
Loss of one copy of the DNA ligase I (LIG1) gene in triple-negative breast cancers (TNBC) with TP53 mutations confers resistance to chemotherapy, but researchers at Baylor College of Medicine and collaborating institutions ...
Medical Xpress / Missing metabolite may drive rare childhood brain disorder, new biosensor reveals
Scientists at Children's Medical Center Research Institute at UT Southwestern (CRI) have discovered why babies born with a rare inborn error of metabolism called GPT2 deficiency suffer from severe neurological impairment. ...
Medical Xpress / Hypoglossal nerve stimulation for obstructive sleep apnea shows downstream health benefits
Researchers estimate that more than 80 million U.S. adults are living with obstructive sleep apnea, a condition in which the soft tissue at the back of the throat collapses and blocks the airway during sleep. This blockage ...
Medical Xpress / GLP-1 shows promise for patients with advanced fatty liver disease
Researchers at the University of California San Diego School of Medicine have reported results from a large international clinical trial showing that semaglutide, a medication in the GLP-1 class of drugs widely used to treat ...
Medical Xpress / Brain circuits may help explain cognitive symptoms in progressive supranuclear palsy
Researchers at Japan's National Institutes for Quantum Science and Technology (QST) have found that tau buildup in progressive supranuclear palsy (PSP) may affect brain networks involved in thinking and behavior. The findings ...
Medical Xpress / Experimental drug may protect the heart in Duchenne muscular dystrophy
Researchers at the USF Health Morsani College of Medicine have identified a potential pathway that could protect cardiac function in people with Duchenne muscular dystrophy (DMD), a progressive and fatal genetic disease that ...
Medical Xpress / Two studies advance sudden cardiac arrest prediction
Warning symptoms, recurrent heart events may identify people at risk for this often-deadly event. Two studies from investigators at Cedars-Sinai Health Sciences University move the medical field closer to solving a longstanding ...
Medical Xpress / Medical spas and pharmacies offering compounded weight-loss drugs despite regulatory concerns
Despite the end of federal shortages of popular GLP-1 weight-loss medications, the market for compounded alternatives remains strong—and some patients may unknowingly be receiving products from pharmacies with concerning ...