Medical Xpress news

Medical Xpress / Working memory may rely on calcium-tuned synaptic boosts, study suggests

Working memory is a cognitive function that is essential for carrying out everyday activities and temporarily retaining information. This process enables us to understand information, learn and manage responses in a controlled ...

12 hours ago
Medical Xpress / How serotonin can be hijacked in the brain

Scientists have uncovered a powerful strategy that the brain uses to coordinate chemical signaling. In a new study, researchers found that in the striatum, a brain region central to learning and moving, one chemical signaling ...

14 hours ago
Medical Xpress / Largest-ever Parkinson's study shows how symptoms differ between men and women

Parkinson's disease is the fastest growing neurological disorder, with more than 10 million cases worldwide. Up to 150,000 Australians currently live with the disease and 50 new cases are diagnosed each day.

16 hours ago
Medical Xpress / Modeling suggests climate change could drive millions into physical inactivity by 2050

Rising temperatures due to climate change could drive millions more adults globally into physical inactivity by 2050, being linked to hundreds of thousands of premature deaths and billions of dollars in lost productivity, ...

9 hours ago
Medical Xpress / Brain computer interface enables rapid communication for two people with paralysis

Loss of communication can be among the most devastating symptoms for patients with paralysis. A new study by investigators from Mass General Brigham Neuroscience Institute and Brown University describes an investigational ...

17 hours ago
Medical Xpress / Gene expression program linked to neurotransmission in the living human brain identified

Researchers have identified a distinct and reproducible gene expression program associated with neurotransmission in the living human brain, offering unprecedented insight into the molecular mechanisms that support human ...

9 hours ago
Medical Xpress / A poorly 'cleaned' brain may increase the risk of psychosis

How can the onset of psychotic symptoms characteristic of schizophrenia be explained? Despite their major and often irreversible impact on intellectual abilities and autonomy, the biological mechanisms that precede their ...

18 hours ago
Medical Xpress / Experimental oral therapy PrimeC shows safety and signals of clinical benefit in ALS

In a phase 2b clinical trial, an investigational oral therapy called PrimeC was found to be safe and well tolerated in people living with amyotrophic lateral sclerosis (ALS), with exploratory findings suggesting target engagement ...

18 hours ago
Medical Xpress / Mapping mental health to deal with the messy reality of psychiatric diagnoses

Depression or ADHD? Neatly delineated diagnoses fail to do justice to the infinitely complex reality that they refer to, argues Eiko Fried in a new paper for JAMA Psychiatry. His proposal: to map the underlying mechanisms ...

11 hours ago
Medical Xpress / How a rare pediatric liver cancer emerges

Liver cancer in children is rare, but when it occurs, the two main types are hepatoblastoma (HB) and hepatocellular carcinoma (HCC). In some cases, however, the tumors show features of both types. These tumors have been classified ...

10 hours ago
Medical Xpress / New genetic risk score better predicts diabetes, obesity and downstream complications

Type 2 diabetes (T2D) and obesity are metabolic conditions with many causes, including overlapping and distinct genetic features. A polygenic risk score (PRS) can capture multiple genetic risk factors to provide an estimate ...

18 hours ago
Medical Xpress / Twice‑yearly injectable HIV regimen treatment demonstrates strong efficacy and safety in Phase 2 trial

A new study published in The Lancet Microbe reports the first twice-yearly injectable HIV treatment regimen—combining lenacapavir, teropavimab, and zinlirvimab—has achieved high rates of viral suppression and demonstrated ...

19 hours ago