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The brain's immune system has long been thought to exist independently from the rest of the body, complete with its own specialized immune cells and a blood-brain barrier that limits what can travel into the brain.

Inherited bone marrow failure syndrome, or IBMFS, describes a group of disorders in which inherited genetic abnormalities impair the bone marrow's ability to produce sufficient healthy blood cells. Patients with these disorders ...

In iScience, scientists outline how they developed a method for generating personality assessment questionnaires with ChatGPT from any source text. To test the method, they applied it to both the DSM-5 and, as a deliberately ...

The encouraging results of the world's first trial of a fridge-free tetanus-diphtheria vaccine could improve access worldwide to crucial treatments while reducing carbon emissions. Fridge-free vaccines have the potential ...

A protein named tau, which has been strongly implicated in the world's No. 1 cause of dementia—Alzheimer's disease—and several other neurodegenerative disorders, may spur these diseases in a way that differs greatly from ...

Scientists have reconstructed the complete genome of a real person, with full sets of chromosomes from each parent, a breakthrough expected to advance research, improve the diagnosis of genetic diseases and make personalized ...

Why do women, on average, live longer than men yet often face a greater burden of chronic disease later in life? Why do some of the most fertile animals in nature, including queen bees and naked mole-rat queens, also live ...

After ovulation, an egg travels through the oviduct (Fallopian tube) toward the uterus (womb). This journey is essential for reproduction: Fertilization normally occurs in the oviduct, and the resulting zygote continues developing ...

A new study from the laboratory of Gemma Carvill, Ph.D., associate professor in the Ken and Ruth Davee Department of Neurology's Division of Epilepsy and Clinical Neurophysiology, has uncovered variants in noncoding regulatory ...

The human body experiences allergic reactions when the immune system mistakenly overreacts to harmless substances, known as allergens, such as pollen, dust or certain foods. While this often causes mild symptoms such as sneezing ...

As women get older, their uterine environment changes. This includes a decrease in a beneficial bacterium called Lactobacillus gasseri, which may make conception—whether natural or via in vitro fertilization—difficult. In ...

To study complex diseases like Alzheimer's, scientists and clinicians analyze how genes change and malfunction in other species. Marmosets, a species of tiny monkey from South America, have become an important animal model ...