Medical Xpress news
Medical Xpress / World's largest genetic study of 'moliness' helps unravel mysteries of melanoma
QIMR Berghofer scientists have uncovered hundreds of genes that play a role in the growth of both moles and melanoma, in a discovery that could lead to new ways of preventing and treating the deadliest form of skin cancer. ...
Medical Xpress / Crohn's atlas maps gene shifts across more than 50 gut cell types
A detailed cellular study of Crohn's disease has mapped how gene activity changes across more than 50 cell types in the gut. The study provides an open resource of the genes that characterize each cell type and those whose ...
Medical Xpress / Genetic cause for rare skin condition points to new therapeutic option
An international team of researchers report in the journal Nature Immunology that a mutation in the gene OTULIN causes pediatric-onset pyoderma gangrenosum, characterized by recurrent ulcerating skin sores. They classify ...
Medical Xpress / Light switch wakes lung cancer cells up from a protective dormant state
Tumor cells can lapse into a sleep-like state and thereby evade the destructive effect of cancer drugs. In some types of the disease, such as certain forms of lung cancer, this state is triggered by stress hormones in the ...
Medical Xpress / Bilingualism may be driven by a single neurological 'grammar engine'
It's not uncommon for bilingual speakers to mistakenly apply the grammatical rules of one language while speaking the other—for example, saying "I have 20 years" instead of "I am 20" when asked about their age.
Medical Xpress / In vivo CRISPR therapy successfully reduces hereditary angioedema attacks in first Phase III trial
Researchers from Amsterdam UMC, in collaboration with other hospitals, have successfully completed the first Phase III study of an in vivo CRISPR therapy. In this large-scale, double-blind trial, 80 patients with hereditary ...
Medical Xpress / Brain stimulation adapts to Parkinson's patients' every step, easing gait and falls
UC San Francisco researchers have developed a new form of deep brain stimulation (DBS) that adjusts in real time as a person walks, helping improve gait and reduce falls in people with Parkinson's disease.
Medical Xpress / Why some immunotherapy fails: Tumor-triggered neutrophils can shut down cancer-killing T cells
Certain white blood cells in the immune system, known as neutrophils, can make cancer immunotherapy less effective, according to a new study from Karolinska Institutet published in the journal Immunity. The results show that ...
Medical Xpress / Why some cancers return: Robotic mini tumor tests point to new ways to target persister cells
Cancer drugs can shrink fast-growing tumors. But sometimes a few tumor cells survive. These "persister" cells seed new tumors, forcing cancer patients into arduous cycles of testing and treatment.
Medical Xpress / The enemy within: How the immune system worsens brain injury outcomes
Traumatic brain injuries (TBI)—even mild concussions—may trigger a chain reaction in the brain that disrupts neuronal communication, long-term memory and cognition, according to University of California, Riverside, research ...
Medical Xpress / Your gut talks to your liver: Study reveals how microbes influence liver function through DNA 'switches'
A study led by scientists from the A*STAR Genome Institute of Singapore (A*STAR GIS) has uncovered how the gut microbiome can influence gene activity in the liver by acting on short stretches of regulatory DNA that function ...
Medical Xpress / Cohabiting people share about a quarter of their gut and oral microbiota, study finds
People who live together share more oral and gut microbes with each other than with other people in their communities, according to a study published in Cell Press Blue. This was true regardless of the cohabitants' relationships—siblings, ...
