Medical Xpress news
Medical Xpress / Diabetes flips immune cells from repair to inflammation in peripheral artery disease, study finds
Type 2 diabetes can turn immune cells that help with tissue repair and anti-inflammatory responses into triggers of chronic inflammation. A recent study investigated why people with type 2 diabetes are at a higher risk of ...
Medical Xpress / Why this CAR T advance matters: Complete remissions without chemotherapy at doses as low as 250,000 cells/kg
Stem-cell memory T (TSCM) cells are a rare subset of immune cells with the ability to self-renew, persist long term, and mount potent anti-tumor responses. These properties make them an attractive candidate for next-generation ...
Medical Xpress / T cells secrete DNA to boost the immune system's cancer-fighting ability
Activated immune cells secrete tiny capsules bearing DNA that can enter other immune and tumor cells to stimulate the body's defense systems, according to a study led by investigators at Weill Cornell Medicine. The discovery ...
Medical Xpress / AI surpasses physicians on clinical reasoning tasks, raising the bar for more serious testing
In one of the largest studies to compare artificial intelligence and physicians on a wide array of clinical reasoning tasks including real emergency department data, a team of physicians and computer scientists at Harvard ...
Medical Xpress / Brazilian tree compounds block SARS-CoV-2 at multiple stages, lab tests show
A study has revealed that galloylquinic acids extracted from the leaves of Copaifera lucens Dwyer, a tree endemic to Brazil primarily found in the Atlantic Forest, have a multi-targeted effect against SARS-CoV-2, the virus ...
Medical Xpress / Restoring protein recycling helps exhausted T cells fight tumors again
T cells are crucial components of our immune system, serving as critical protectors against infection and disease. But there are limits to their defensive capabilities. T cells are not inexhaustible protectors. Often, when ...
Medical Xpress / Genetic discovery may explain why pancreatic cancer is so difficult to treat
Pancreatic cancer can remain quiet for years, developing undetected before causing symptoms that lead to a diagnosis. Even after a surgeon removes a pancreas tumor, other cells often hide and erupt later. But University of ...
Medical Xpress / Host genetics and sex can steer flu toward greater virulence, mouse experiments reveal
During the early stages of a pandemic, viruses tend to evolve in ways that enhance their ability to reproduce and spread, rather than to evade the host's immune system. The genetics and sex of the host influence how a novel ...
Medical Xpress / No live animal testing needed: Lab-grown airway organoids reveal viral infection in wildlife species
Experimental infections, where a pathogen is introduced into the host body to see its effects in action, are considered the gold standard for assessing how vulnerable a host is, offering clear insights into how a pathogen ...
Medical Xpress / For 30 years, doctors chased the wrong immune culprit behind this rare inflammatory disease
Researchers at the Garvan Institute of Medical Research have uncovered a critical mechanism driving inflammation in mevalonate kinase deficiency (MKD), a rare but devastating autoinflammatory disorder. The study, published ...
Medical Xpress / Communication from the CDC fuels skepticism about vaccines and science, research suggests
The scientific consensus is that vaccinations are neither causally nor statistically linked to autism. The US health authority CDC changed its official communication on this matter and instead emphasized a connection could ...
Medical Xpress / Severe narcolepsy found to damage a second brain region
For nearly 25 years, scientists believed they knew what caused the most severe form of narcolepsy. A new UCLA Health study now suggests they were only half correct. In a study published in Nature Communications, UCLA Health ...