Medical Xpress news
Medical Xpress / Targeting cell division protein CDK2 could boost immunotherapy response across a wide range of cancers
New research from Dana-Farber Cancer Institute scientists suggests that cyclin-dependent kinase 2 (CDK2) inhibitors, which are currently being tested as treatments that slow the growth of a narrow range of cancers, could ...
Medical Xpress / Cerebroid study hints at how maternal inflammation may influence fetal brain development
Past studies suggest that a mother-to-be's heightened immune responses during pregnancy are linked to a higher risk of conditions affecting their offspring's brain development. While this association is well documented, the ...
Medical Xpress / Immediate coronary angiography fails to boost survival after cardiac arrest, trial finds
Immediate coronary angiography did not improve 30-day survival compared with a deferred strategy in patients without ST-segment elevation on an ECG after out-of-hospital cardiac arrest. These were the main findings of the ...
Medical Xpress / Traumatic brain injury recovery follows different neurological paths with age
Conventional wisdom holds that younger brains are better equipped to recover from injury. Their greater flexibility allows them to adapt, rebuild connections and compensate for damage in ways older brains often cannot. But ...
Medical Xpress / NFL settlement testing may miss measurable cognitive decline in players with advanced CTE
Researchers at Boston University have completed the largest study to date characterizing the cognitive symptoms of NFL players with confirmed chronic traumatic encephalopathy (CTE) who underwent neuropsychological tests while ...
Medical Xpress / Local neural wiring may set the brain's range of activity patterns
The human brain contains billions of neurons, specialized nerve cells that receive, transmit and process information through electrical and chemical signals. Human thoughts, sensory perceptions and behaviors are known to ...
Medical Xpress / Aging blocks the retina's ability to regrow lost neurons, a first-of-its-kind study finds
A new study from the laboratory of Levi Todd, Ph.D., at Upstate Medical University has found that aging significantly limits the ability of support cells in the retina, called glia, to be reprogrammed into new neurons, a ...
Medical Xpress / CRISPR gene-editing therapy safely and continuously lowers cholesterol and triglycerides, first-in-human trial shows
A Cleveland Clinic first-in-human clinical trial has shown that a one-time infusion of a gene-editing therapy using CRISPR-Cas9 was effective and safe in reducing LDL ("bad") cholesterol and triglycerides in people with medication-resistant ...
Medical Xpress / Energy-hungry tissues expand cleanup crews to clear worn-out mitochondria
The body's heart muscle (for pumping blood), skeletal muscle (for movement and posture) and brown fat (for heat production) each require a lot of energy and make a lot of waste. That waste needs to be managed.
Medical Xpress / Cancer drug tames atherosclerosis inflammation and plaque in animal models
A new Yale study has identified a promising therapeutic avenue for atherosclerosis, a condition caused by inflammation and plaque buildup in arteries. Martin Schwartz, Ph.D., Robert W. Berliner Professor of Medicine (Cardiology) ...
Medical Xpress / Rethinking radiotherapy may boost immunotherapy for pancreatic cancer
Pancreatic cancer remains one of the most aggressive malignancies, with a particularly poor prognosis even when diagnosed at a localized stage. In a paper published in Nature Reviews Gastroenterology & Hepatology, researchers ...
Medical Xpress / Early mitochondrial stress reveals potential mechanism for lasting heart protection
Mitochondria are popularly known as the "powerhouse of the cell," but these cellular structures do much more—including acting as signaling hubs. Some signals that mitochondria send can reprogram the activity of the entire ...
