Medical Xpress news
Medical Xpress / New strategy could prevent T cell exhaustion and boost immunotherapy
A major pillar of cancer immunotherapy involves stimulating T cells, the specialized killers of the immune system, to attack tumors. But this strategy has been undermined by the tendency of T cells to tire out before finishing ...
Medical Xpress / Misfolded DNA blueprint: A new origin for genetic disease
Congenital heart disease is the most common birth defect, affecting approximately 1 in 100 babies born each year. One of the many causes of this disorder is having only one functional copy of the gene TBX5, rather than the ...
Medical Xpress / Gene regulation map reveals treatment targets for heart failure
Researchers from the University of California San Diego have created the most detailed map to date of how gene regulation breaks down in human heart failure, revealing how genes are controlled in specific cell types as the ...
Medical Xpress / From urinary tract infection to brain abscess: How bacterial subpopulations can spread to distant body sites
Researchers from the University of Cologne, the German Center for Infection Research (DZIF), and the Broad Institute of Harvard and MIT present a clinical case in the New England Journal of Medicine that provides new insights ...
Medical Xpress / How systemic immune regulation is 'hijacked' during tumor progression
The immune system plays a critical role in protecting the body from cancer by recognizing and eliminating abnormal cells before they can develop into tumors. This process relies on T cells that can recognize tumor-derived ...
Medical Xpress / Two new therapies and rapid tests could reshape drug-resistant gonorrhea care
Drug-resistant Neisseria gonorrhoeae (the bacterium that causes gonorrhea) has become one of the most urgent antimicrobial-resistant threats to public health worldwide. Clinicians expect to be confronted by rising rates of ...
Medical Xpress / Chemotherapy leaves detectable DNA fingerprints in childhood tumors within 18 months
Nearly half of childhood tumors treated with common types of chemotherapy showed detectable DNA changes linked to treatment within 18 months, according to a new international study led by The Hospital for Sick Children (SickKids). ...
Medical Xpress / Parents' socioeconomic status is more important than prenatal behaviors to a future child's health, study suggests
Family socioeconomic position may be a more important determinant of children's health than parental behaviors such as smoking, drinking or caffeine consumption, according to a study published in PLOS Medicine by Gemma Sharp ...
Medical Xpress / Mass-producible immune cells kill patient-derived colorectal tumors in mice
Off-the-shelf and mass-producible immune cells fight solid human tumors engrafted in mice. The Kobe University development is a significant contribution toward faster, cheaper cancer immunotherapy.
Medical Xpress / Drug temporarily reverses autism-like brain changes in adult mice within hours
A new mouse study led by UCLA Health suggests that inflammation during pregnancy can trigger autism-like changes in offspring, but those brain and behavioral effects may be rapidly, though temporarily, reversible in adulthood ...
Medical Xpress / Study reveals how networks of switches in DNA, which regulate gene expression, drive cancer growth
Enhancers are pieces of DNA that act like switches, regulating when genes are turned on and off and how strongly they are activated. Scientists know these switches play a critical role in cancer and other diseases, but they ...
Medical Xpress / Imaging platform captures electrical activity from nearly 200 neurons deep in living brain tissue
The brain is a vast, densely interconnected network of neurons computing in parallel. Watching these computations unfold in real time could reveal how the brain processes sensation and guides behavior. But the electrical ...
