Medical Xpress news
Medical Xpress / New analytical method reveals how drug combinations act in leukemia
Acute myeloid leukemia (AML) remains one of the most difficult blood cancers to treat. Although drug combinations are often more effective than single agents, their true mechanisms of action have been poorly understood. A ...
Medical Xpress / Blocking NOX-1 enzyme may extend ketamine's antidepressant effects
Treatment-resistant depression affects a large proportion of people with major depressive disorder, and while ketamine offers rapid relief, its antidepressant effects fade within a few weeks. Now, researchers from Japan have ...
Medical Xpress / Global trial shows targeted heart drug reduces obstructive hypertrophic cardiomyopathy in youth
A global clinical trial involving The Hospital for Sick Children (SickKids) has found that mavacamten—a heart medication previously approved for adults—can safely and effectively improve the flow of blood through compromised ...
Medical Xpress / Burnout may lead family doctors to leave medicine
Family physicians who report feeling burned out are nearly 1.5 times more likely to change practices or stop practicing medicine entirely than their peers who don't report burnout, a study by Weill Cornell Medicine researchers ...
Medical Xpress / How bacteria outsmart the immune system: Two-pronged strategy revealed
Researchers have uncovered how a disease-causing bacterium uses a single protein to interfere with the body's defenses in more than one way, offering a clearer picture of how infections take hold at the cellular level. The ...
Medical Xpress / Jail-based programs could dramatically reduce hepatitis C infections
A Stanford study shows that jail-based hepatitis C programs could cut new infections by nearly half among people who inject drugs, potentially providing a major boost to lagging U.S. efforts to meet national hepatitis C elimination ...
Medical Xpress / Antimicrobial resistant genes found in wastewater samples from a South African city
In South Africa, wastewater treatment plants (WWTPs) and connected river systems could serve as reservoirs of antibiotic resistance, raising fresh concerns about how antimicrobial resistance moves through ecosystems and into ...
Medical Xpress / Precision medicine helps more patients receive a genetic diagnosis
A collaboration between Karolinska Institutet, Karolinska University Hospital, and SciLifeLab has integrated whole genome sequencing into routine diagnostic investigations for rare diseases at Karolinska University Hospital. ...
Medical Xpress / A new lens on autism's sex bias: How X chromosome 'escape' genes could shape risk
Autism has a significant and enduring sex bias, with roughly four boys diagnosed for every girl. For many years, experts have believed this disparity arises primarily from diagnostic inequities because much of autism research—and ...
Medical Xpress / Newly discovered recessive neurodevelopmental disorder may be most prevalent ever
Researchers at the Icahn School of Medicine at Mount Sinai in New York have identified and described a previously unknown recessive neurodevelopmental disorder (NDD) that appears to be the most prevalent ever discovered. ...
Medical Xpress / Autism risk genes are shared across ancestries, research reveals
A new study, co-led by researchers at the Icahn School of Medicine at Mount Sinai and published March 30 in Nature Medicine, demonstrates that genes associated with autism risk are largely the same across people of different ...
Medical Xpress / Boosting good gut bacteria population through targeted interventions may slow cognitive decline
The origin of neurodegenerative diseases like Alzheimer's or dementia isn't limited to the brain. The state of your gut can quietly set off a cycle of chronic, system-wide inflammation that nudges the brain toward cognitive ...