Medical Xpress news

Medical Xpress / Breast cancer drug boosts leukemia treatment: Unexpected duo shows promise in overcoming resistance

A research team at Oregon Health & Science University has discovered a promising new drug combination that may help people with acute myeloid leukemia overcome resistance to one of the most common frontline therapies.

Dec 29, 2025 in Medications
Medical Xpress / B cells temporarily regain stem-like flexibility, increasing risk of lymphoma formation

Immune cells called B cells make antibodies that fight off invading bacteria, viruses and other foreign substances. During their preparation for this battle, B cells transiently revert to a more flexible (plastic) stem-cell-like ...

Dec 29, 2025 in Medical research
Medical Xpress / AI-powered knowledge graph links heart images to genes and drug predictions

Knowledge graphs are a powerful tool for bringing together information from biological databases and linking what is already known about genes, diseases, treatments, molecular pathways and symptoms in a structured network. ...

Dec 29, 2025 in Cardiology
Medical Xpress / Blocking a key gene regulator may restore immune response in cancer therapy

Immune checkpoint inhibitors (ICIs) have revolutionized cancer therapy by harnessing the body's immune system to target tumors. Despite their initial clinical success, many patients eventually experience diminished therapeutic ...

Dec 29, 2025 in Oncology & Cancer
Medical Xpress / Inhibiting PGAM-Chk1 binding in the senescent cells of mice appears to slow aging

Aged and frail people often suffer a decline in tissue reserve capacity during aging. This reserve, called resilience, helps the body maintain homeostasis through various defense, compensation, modulation, and repair responses. ...

Dec 29, 2025 in Gerontology & Geriatrics
Medical Xpress / Candida auris spreads globally as drug resistance and virulence increase, review finds

The fungal species Candida auris is spreading across the globe, and gaining in virulence, according to a new review by a Hackensack Meridian Center for Discovery and Innovation (CDI) scientist and colleagues.

Medical Xpress / AI model forecasts speech development in deaf children after cochlear implants

An AI model using deep transfer learning—the most advanced form of machine learning—has predicted spoken language outcomes with 92% accuracy from one to three years after patients received cochlear implants (implanted ...

Medical Xpress / How stroke influences speech comprehension

Following a stroke, some people experience a language disorder that hinders their ability to process speech sounds. How do their brains change from stroke?

Dec 29, 2025 in Psychology & Psychiatry
Medical Xpress / AI-designed protein shows 50% greater anti-inflammatory effect in animal studies

A research team has developed a next-generation anti-inflammatory protein using AI and supercomputing.

Dec 29, 2025 in Inflammatory disorders
Medical Xpress / Low-dose peanut therapy shown to protect children with peanut allergies

Children with peanut allergies may not need large doses of peanut oral immunotherapy (OIT) to build protection against peanuts, finds a new study led by The Hospital for Sick Children (SickKids) and Montreal Children's Hospital.

Dec 29, 2025 in Immunology
Medical Xpress / Researchers turn cancer resistance mutations into targets for new immunotherapies

One of the most challenging moments in cancer treatment comes when a therapy stops working. In many metastatic cancers, drugs that are initially effective lose their potency over time, as malignant cells acquire mutations ...

Dec 29, 2025 in Oncology & Cancer
Medical Xpress / How doubting your doubts may increase your commitment to goals

When it comes to our most important long-term goals in life, it is not uncommon to face obstacles that may lead us to doubt whether we can achieve our ambitions.

Dec 29, 2025 in Psychology & Psychiatry