Medical Xpress news
Medical Xpress / Vascularized liver tissueoid-on-a-chip models regeneration and transplant rejection
Dr. Vadim Jucaud's lab at the Terasaki Institute has developed a vascularized liver tissueoid-on-a-chip (LToC) platform that recapitulates key structural, functional, and immunological features of human liver tissue, enabling ...
Medical Xpress / Missing ANGPTL4 gene in mice reprograms immunity, shielding against gut inflammation
A novel study using a mouse model has found that the absence of the angiopoietin-like 4 (ANGPTL4) protein during development triggers a long-lasting reprogramming of the immune system that protects against intestinal inflammation. ...
Medical Xpress / Study splits schizophrenia genetic risk into two pathways, one shared with bipolar disorder
A new study by researchers at King's College London has split schizophrenia risk into two genetically distinct pathways. One is characterized by a shared genetic risk with bipolar disorder and associated with higher educational ...
Medical Xpress / Heart attack study reveals 'survival paradox'
Research from the University of Leicester and NIHR challenges the "one-size-fits-all" approach to heart attack care, adding critical nuance to the debate on sex disparities. A new study involving more than 900,000 patients ...
Medical Xpress / Aggressive oral cancer can be identified at an early stage by changes in lymphatic vessels
Oral cancers with a high risk of recurrence can be identified at an early stage by examining the lymphatic vessels of the tumor. Finnish researchers have discovered for the first time that the surface cells of the lymphatic ...
Medical Xpress / Docetaxel rechallenge linked to longer survival than cabazitaxel, study suggests
A common clinical question for medical oncologists treating metastatic castration-resistant prostate cancer is, should patients who previously received docetaxel and progress on it, reuse docetaxel or switch to cabazitaxel ...
Medical Xpress / A single sample classifier can predict cancer-associated fibroblast subtypes in patient samples
In a collaboration between several labs at UNC Lineberger, researchers have defined cancer-associated fibroblast (CAF) subtypes that are clinically robust, prognostic, and predictive of immunotherapy response and developed ...
Medical Xpress / Aortic stenosis: 200 newly identified genes raise hope for future treatments
A new study on aortic stenosis, the most common form of heart valve disease, has identified more than 200 new genes that predispose individuals to this condition, for which no treatment currently exists. The discovery of ...
Medical Xpress / KRAS mutation type may guide more effective cancer treatments
KRAS is the most frequently mutated oncogene across all human cancers. Although different KRAS mutations have long been thought to exert the same cancer-driving effects, a new study led by UT Southwestern Medical Center researchers ...
Medical Xpress / Vaccine shows protection against severe childhood diarrhea
Each year, tens of thousands of children under 5 die from diarrheal disease caused by enterotoxigenic Escherichia coli (ETEC), primarily in low-income countries. A new ETEC vaccine has shown promising results in reducing ...
Medical Xpress / Largest study of rare skin cancer in Mexican patients shows that it is more complex than previously thought
Genetic ancestry may play a key role in how acral melanoma, a rare and aggressive type of skin cancer, develops and behaves, with important implications for diagnosis and treatment, according to researchers at the Wellcome ...
Medical Xpress / Scientist invents super-chipped shoe to help his 89-year-old mentor avoid falling
When a big-hearted engineer noticed his 89-year-old mentor was unsteady on his feet, he sprang into action and created a futuristic shoe that could in the future help him—and scores of other older people—keep their balance. ...
