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Medical Xpress / Targeting the untargetable cancer—rezatapopt, an oral p53 reactivator

Memorial Sloan Kettering Cancer Center investigators and collaborators have tested rezatapopt, an oral p53 reactivator designed for tumors with TP53 Y220C, and observed antitumor activity across multiple solid tumor types ...

Mar 2, 2026 in
Medical Xpress / Painless skin patch offers new way to monitor immune health

Researchers at The Jackson Laboratory (JAX), in collaboration with the Massachusetts Institute of Technology (MIT), have developed the first bandage-like microneedle patch that can sample the body's immune responses painlessly ...

Mar 2, 2026 in
Medical Xpress / Supposedly harmless peptide may be linked to Alzheimer's disease

While companies developing drugs to treat Alzheimer's disease have spent decades and many billions of dollars targeting amyloid beta due to its role in clogging patients' brains with harmful deposits, a biochemist at the ...

Mar 2, 2026 in
Medical Xpress / Breast cancer still most common cancer among women worldwide, with annual cases expected to exceed 3.5 million by 2050

Despite recent advancements in breast cancer treatments, new breast cancer cases in women are predicted to rise by a third globally from 2.3 million in 2023 to more than 3.5 million in 2050. Similarly, yearly deaths from ...

Mar 2, 2026 in
Medical Xpress / AI cancer tools may rely on 'shortcut learning' rather than genuine biological signals

Artificial intelligence tools are increasingly being developed to predict cancer biology directly from microscope images, promising faster diagnoses and cheaper testing. But new research from the University of Warwick, published ...

Mar 2, 2026 in
Medical Xpress / New diagnostic markers for multiple sclerosis discovered in cerebrospinal fluid

Researchers from the MPI of Biochemistry and the Technical University of Munich have discovered new diagnostic markers for multiple sclerosis (MS), a disease that affects 3 million people worldwide. Using mass spectrometry, ...

Mar 2, 2026 in
Medical Xpress / Cell-free DNA offers early warning for bloodstream infections in kids with leukemia

Researchers have identified a promising way to predict bloodstream infections in children with high-risk leukemia days before the infection would be diagnosed using current standards of care. The test, named plasma microbial ...

Mar 2, 2026 in
Medical Xpress / How dysfunctional packaging of dopamine advances symptoms of Parkinson's disease

A new study shows how dysfunctional packaging of the neurotransmitter dopamine triggers toxic processes in neurons—and how this can be repaired with simple delivery of energy (ATP). Parkinson's gradually destroys dopamine-producing ...

Mar 2, 2026 in
Medical Xpress / A molecular 'switch' could make pancreatic cancer more treatable

Scientists at Duke-NUS Medical School have identified a molecular "switch" that determines whether pancreatic cancer cells resist chemotherapy or respond to it—a finding that could help convert some of the most treatment-resistant ...

Mar 2, 2026 in
Medical Xpress / Smart patch detects allergies before symptoms strike

A wearable device that alerts people with food allergies before a reaction begins has the potential to reduce life-threatening anaphylaxis and transform allergy management from reactive to preventive care. The AllergE patch ...

Mar 2, 2026 in
Medical Xpress / Low-dose lithium may slow verbal memory decline, exploratory clinical trial suggests

Lithium—a decades-old treatment for bipolar disorder—may hold potential neuroprotective benefits beyond mood stabilization. An exploratory clinical trial from the University of Pittsburgh suggests that low-dose oral lithium ...

Mar 2, 2026 in
Medical Xpress / Self-aware biosensors boost digital health monitoring

Smart biomedical devices are transforming modern health care, using skin-mounted sensors to capture in-depth health information directly from the body. As clinicians increasingly use biosensing devices to guide patient care, ...

Mar 2, 2026 in