Medical Xpress news
Medical Xpress / Why some immunotherapy fails: Tumor-triggered neutrophils can shut down cancer-killing T cells
Certain white blood cells in the immune system, known as neutrophils, can make cancer immunotherapy less effective, according to a new study from Karolinska Institutet published in the journal Immunity. The results show that ...
Medical Xpress / The enemy within: How the immune system worsens brain injury outcomes
Traumatic brain injuries (TBI)—even mild concussions—may trigger a chain reaction in the brain that disrupts neuronal communication, long-term memory and cognition, according to University of California, Riverside, research ...
Medical Xpress / AI-assisted, real-time deep-brain stimulation therapy for walking impairments in Parkinson's disease
Deep brain stimulation (DBS) has been used for more than three decades to treat motor symptoms of Parkinson's disease. Today, more than 200,000 patients worldwide have been implanted with these systems, which continuously ...
Medical Xpress / An economic case for teen weight-loss surgery
Metabolic and bariatric surgery for teens with severe obesity was found to be cost-effective over 10 years, according to a new analysis from Ann & Robert H. Lurie Children's Hospital of Chicago published in JAMA Network Open. ...
Medical Xpress / Blueberry-size capsule tracks core temperature from inside the body
In a hospital or at home, temperatures are usually taken using an oral or forehead thermometer, but these do not always accurately reflect core body temperature. Measuring core temperature from within the body could make ...
Medical Xpress / Your gut talks to your liver: Study reveals how microbes influence liver function through DNA 'switches'
A study led by scientists from the A*STAR Genome Institute of Singapore (A*STAR GIS) has uncovered how the gut microbiome can influence gene activity in the liver by acting on short stretches of regulatory DNA that function ...
Medical Xpress / CAR T-cell therapy shows early promise in severe lupus
Early results from a UCL- and UCLH-led clinical trial suggest that a type of CAR T-cell therapy—developed by Autolus Therapeutics, a UCL spinout—could offer a new treatment approach for people with severe, treatment-resistant ...
Medical Xpress / AI deciphers how fast ALS progresses and which functions decline first
ALS (amyotrophic lateral sclerosis) is a fatal neurodegenerative disease that gradually affects a person's ability to move, speak and breathe. It advances differently in every patient. Now, researchers at Nagoya University ...
Medical Xpress / Mitochondria reveal new TDP-43 signaling route tied to ALS and dementia
A new study published in Nature Communications has uncovered a communication pathway between mitochondria and RNA granules that may help scientists understand how the toxic buildup of the TDP-43 protein leads to the development ...
Medical Xpress / Genetic marker may flag severe IBD earlier in some patients
In the largest genetic study of inflammatory bowel disease (IBD) traits to date, researchers have identified a genetic marker associated with more severe ulcerative colitis and Crohn's disease—the major forms of IBD.
Medical Xpress / Inside failing joints: How wear and corrosion reshape hip and knee implants over time
Orthopedic implants are designed to restore movement and relieve pain, offering patients a second or even third chance at mobility. A hip or knee replacement is often framed as a durable fix, engineered to last for years, ...
Medical Xpress / Combo treatment delays multiple myeloma progression and may improve survival, study finds
Patients with multiple myeloma who received a new immunotherapy combination lived significantly longer without their cancer worsening and showed early signs of improved survival in a large international clinical trial.