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Prostate tumors can rewire amino acid metabolism to override the normal brakes on cholesterol production, a process that may fuel hormone therapy resistance, according to a study by Weill Cornell Medicine investigators.

A review published in Nature Reviews Cardiology provides the most detailed picture yet of how nicotine damages the cardiovascular system—tracing the biological chain of events from the moment nicotine binds to receptors in ...

Immunotherapy has transformed outcomes for many cancer patients. Unlike conventional treatments, these therapies do not attack tumors directly. Instead, they enable the body's immune system to identify and kill cancer cells ...

University of Alabama researchers have found that a combination of an existing immunosuppressant drug and a compound derived from dietary sources showed greater benefit than either treatment alone in a preclinical model of ...

Mayo Clinic researchers have estimated the risk that pancreatic cysts with worrisome or high-risk features will progress to pancreatic cancer or advanced precancerous changes within three years. The findings, published in ...

Researchers at The University of Texas MD Anderson Cancer Center found that, in preclinical models of colorectal cancer, tumors can start damaging peripheral nerves before chemotherapy begins. These findings suggest tumor-related ...

A new way of delivering therapist-led online cognitive behavioral therapy (CBT) can reduce symptoms of depression and improve function, according to new University of Bristol-led research published in The Lancet Primary Care.

With more than 7 million Americans living with Alzheimer's dementia—a number projected to reach nearly 13 million by 2050—new Emory University research suggests that higher vitamin D supplement intake may be associated with ...

A compound produced in the body after eating pomegranates improves heart function by up to 80% in a type of heart failure with limited treatment options.

Memory clinics still rely on visual rating scales to assess brain atrophy, yet these tools lack the sensitivity to catch subtle changes associated with early dementia. A measure of how old a person's brain appears on brain ...

The human immune system has specialized cells called CD4 cytotoxic T lymphocytes (CD4 CTLs), which have been shown to kill tumor cells in some cancers. When a person gets sick, these cells multiply in a process called clonal ...

Researchers at Karolinska Institutet have discovered that gut bacteria can convert dietary nitrate and iron into protective molecules that may reduce the risk of cardiovascular and metabolic diseases. The study, published ...