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A marathon, 100 kilometers (62 miles) or even 230 kilometers (143 miles) in a single effort: Anyone running such distances puts enormous strain on their body. At the same time, levels of the body's own cannabis-like signaling ...

Hyperventilating. Breath-holding until they turn blue. This abnormal breathing is frequent and disturbing in people with Rett syndrome, a rare genetic disease. Now University of Connecticut researchers report in Current Biology ...

Researchers blocked a naturally occurring molecule to reverse pulmonary arterial hypertension in preclinical models, a finding that could point to a new treatment approach for people with a rare and often fatal lung disease.

Where and how does an Alzheimer's tangle begin? A new study by neuroscientists at Columbia University challenges a long-held assumption about the source of toxic tau proteins, which form neurofibrillary tangles and are closely ...

With a five-year survival rate of barely 5%, glioblastoma remains one of the deadliest brain cancers. First-line treatment consists of surgery to remove as much tumor tissue as possible.

A genetic marker already used to flag the risk of a life-threatening reaction to the antibiotic vancomycin also identifies patients at risk of that reaction to lamotrigine—and it is missing from the gene panels clinicians ...

Daraxonrasib, an oral RAS inhibitor therapy, achieved durable responses in pretreated patients with RAS-mutant non-small cell lung cancer (NSCLC) in a phase 1/2 trial led by The University of Texas MD Anderson Cancer Center.

UIC researchers have identified two therapeutic targets for pulmonary arterial hypertension, an as-yet-incurable disease that can be caused by a parasite laying eggs in the abdomen. The targets represent an opportunity to ...

Northwestern Medicine scientists have developed a novel high-resolution spatial genomics platform that may enhance future research into how genome organization and genetic alterations contribute to disease development, including ...

Liver cancer is difficult to treat because tumors vary greatly from patient to patient. Researchers at the University of Basel have captured this diversity by creating a collection of mini-tumors, which they use to systematically ...

Scientists study the underlying causes of a disease or test potential new drugs in animal models or cells obtained from human biopsy specimens before clinical trials. However, disease models in animals do not mimic actual ...

For A. Campbell Sullivan, PsyD, this time it's personal. As a neuropsychologist and clinical associate professor of neurology at the Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases at UT Health San Antonio, ...