Medical Xpress news
Medical Xpress / New strategy could prevent T cell exhaustion and boost immunotherapy
A major pillar of cancer immunotherapy involves stimulating T cells, the specialized killers of the immune system, to attack tumors. But this strategy has been undermined by the tendency of T cells to tire out before finishing ...
Medical Xpress / Multi-omics map paves way for personalized medicine in Down syndrome
In a recent study published in Nature Communications, researchers from the University of Colorado Anschutz Linda Crnic Institute for Down Syndrome (Crnic Institute) discovered unique biological processes altered among individuals ...
Medical Xpress / Molecular imaging enhances diagnosis of fever of unknown origin
PET/CT can add valuable information to aid the diagnosis of fever of unknown origin (FUO), according to a new multicenter, retrospective study published in the June issue of The Journal of Nuclear Medicine. In a cohort of ...
Medical Xpress / Two ways to read a genome: Body-wide, single-cell atlas maps DNA folding and methylation together
Every cell in the human body carries the same 3 billion letters of DNA, yet a neuron, a heart muscle cell and a pancreatic beta cell each use that shared code to do entirely different jobs. How cells pull off this trick comes ...
Medical Xpress / Chemotherapy leaves detectable DNA fingerprints in childhood tumors within 18 months
Nearly half of childhood tumors treated with common types of chemotherapy showed detectable DNA changes linked to treatment within 18 months, according to a new international study led by The Hospital for Sick Children (SickKids). ...
Medical Xpress / Children with severe pneumonia can leave hospital sooner after switching to oral antibiotics, trial shows
Children hospitalized with severe pneumonia can safely switch from injectable to oral antibiotics once they begin to recover, allowing many to return home sooner and complete treatment outside the hospital. That is according ...
Medical Xpress / Gene regulation map reveals treatment targets for heart failure
Researchers from the University of California San Diego have created the most detailed map to date of how gene regulation breaks down in human heart failure, revealing how genes are controlled in specific cell types as the ...
Medical Xpress / Misfolded DNA blueprint: A new origin for genetic disease
Congenital heart disease is the most common birth defect, affecting approximately 1 in 100 babies born each year. One of the many causes of this disorder is having only one functional copy of the gene TBX5, rather than the ...
Medical Xpress / How systemic immune regulation is 'hijacked' during tumor progression
The immune system plays a critical role in protecting the body from cancer by recognizing and eliminating abnormal cells before they can develop into tumors. This process relies on T cells that can recognize tumor-derived ...
Medical Xpress / From urinary tract infection to brain abscess: How bacterial subpopulations can spread to distant body sites
Researchers from the University of Cologne, the German Center for Infection Research (DZIF), and the Broad Institute of Harvard and MIT present a clinical case in the New England Journal of Medicine that provides new insights ...
Medical Xpress / Two new therapies and rapid tests could reshape drug-resistant gonorrhea care
Drug-resistant Neisseria gonorrhoeae (the bacterium that causes gonorrhea) has become one of the most urgent antimicrobial-resistant threats to public health worldwide. Clinicians expect to be confronted by rising rates of ...
Medical Xpress / Parents' socioeconomic status is more important than prenatal behaviors to a future child's health, study suggests
Family socioeconomic position may be a more important determinant of children's health than parental behaviors such as smoking, drinking or caffeine consumption, according to a study published in PLOS Medicine by Gemma Sharp ...
