Medical Xpress news

Medical Xpress / Protein unties tangled DNA linked to hotspots of cancer mutations

New research published in Nature Communications has linked a normal cellular process to an accumulation of DNA mutations in cancer and identified cancer-driving mutations in an underexplored part of the genome.

Dec 4, 2025 in Oncology & Cancer
Medical Xpress / KRAS-mutant cancers: Potential target could overcome treatment resistance

Researchers at The University of Texas MD Anderson Cancer Center have identified a specific protein, RASH3D19, that is responsible for activation of RAS signaling pathways involved in aggressive tumor growth and resistance ...

Dec 4, 2025 in Oncology & Cancer
Medical Xpress / Backup DNA repair system could be cancer's weak spot

The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break—when both sides of the DNA helix are cut at once. Healthy cells can normally fix these breaks using highly ...

Dec 4, 2025 in Oncology & Cancer
Medical Xpress / Visualizing neural connections in 3D with a new microscopy technique

Leiden researchers can now visualize the connections between brain cells. Their microscopy technique could significantly advance the human quest to understand brain functions. The study is published in the Proceedings of ...

Dec 4, 2025 in Neuroscience
Medical Xpress / One experiment, two insights: Sequencing method reveals both genome proteins and their positions

A team from the Andalusian Center for Molecular Biology and Regenerative Medicine (CABIMER) has developed an innovative technique called PLAMseq (proximity-labeled affinity-purified mass spectrometry plus sequencing) that, ...

Dec 4, 2025 in Genetics
Medical Xpress / Early normalization of weight can protect the heart from childhood overweight

Overweight as a child is not necessarily a risk factor for heart attack later in life. If weight is normalized before adulthood, the heart seems unaffected by the higher childhood BMI, according to a study conducted at the ...

Dec 4, 2025 in Cardiology
Medical Xpress / Exploring the link between RNA modification and prostate cancer growth

A Northwestern Medicine study published in the Journal of Clinical Investigation has uncovered a connection between a well-known cancer-related protein and a major RNA modification process, which may inform new treatment ...

Dec 4, 2025 in Oncology & Cancer
Medical Xpress / T cells found in tonsils differ in key ways from those in blood

T cells, also known as lymphocytes, are a type of white blood cell that play an important role in the body's immune response. Historically, blood samples have been used to monitor how T cells respond to a virus, vaccine or ...

Dec 4, 2025 in Immunology
Medical Xpress / Microglia replacement paves way for neurodegenerative disease therapies, moving from mice to humans in just 5 years

Tiny immune cells called microglia protect the central nervous system (CNS) in a multitude of ways: They provide innate immunity, shape neurodevelopment, maintain homeostasis and modulate neurological disorders. That functionality ...

Dec 4, 2025 in Neuroscience
Medical Xpress / Gestational diabetes: Continuous glucose monitoring can reduce risk of excessive birth weight

An international research team led by the Medical University of Vienna has shown that continuous glucose monitoring (CGM) in women with gestational diabetes can reduce the risk of a newborn with above-average birth weight. ...

Dec 4, 2025 in Diabetes
Medical Xpress / To treat long COVID, we must learn from historical chronic illnesses, medical researchers say

In a paper published in Trends in Immunology, scientists and doctors highlight the importance of studying long COVID in the context of other post-acute infection syndromes or chronic illnesses. By analyzing historical accounts ...

Medical Xpress / Animals may feel like us, but the way we think is different

Children universally believe animals experience emotions and feelings but are reluctant to say they have human-like thoughts, which can influence how we treat other species throughout life, according to a new study. Forrest ...

Dec 4, 2025 in Psychology & Psychiatry