Medical Xpress news
Medical Xpress / Gene activity in blood fluctuates more than expected—and that has consequences for medicine
Take a blood sample from someone in the dead of winter. Take another in midsummer. Same person, same laboratory. And yet, at the level of gene activity, the molecular picture can look surprisingly different. This is not an ...
Medical Xpress / New immune mechanism helps explain why ovarian cancer stops responding to chemotherapy
Scientists at The Wistar Institute have identified a new mechanism behind the chemotherapy resistance that makes ovarian cancer so lethal. In a new study published in The Journal for ImmunoTherapy of Cancer, the researchers ...
Medical Xpress / New strategy could prevent T cell exhaustion and boost immunotherapy
A major pillar of cancer immunotherapy involves stimulating T cells, the specialized killers of the immune system, to attack tumors. But this strategy has been undermined by the tendency of T cells to tire out before finishing ...
Medical Xpress / Persistent money struggles tied to faster brain aging
Persistent financial hardship accelerates age-related cognitive decline, according to a new study led by University College London (UCL) researchers. The study, published in Innovation in Aging, looked at data from 2,759 ...
Medical Xpress / Multi-omics map paves way for personalized medicine in Down syndrome
In a recent study published in Nature Communications, researchers from the University of Colorado Anschutz Linda Crnic Institute for Down Syndrome (Crnic Institute) discovered unique biological processes altered among individuals ...
Medical Xpress / Two ways to read a genome: Body-wide, single-cell atlas maps DNA folding and methylation together
Every cell in the human body carries the same 3 billion letters of DNA, yet a neuron, a heart muscle cell and a pancreatic beta cell each use that shared code to do entirely different jobs. How cells pull off this trick comes ...
Medical Xpress / Molecular imaging enhances diagnosis of fever of unknown origin
PET/CT can add valuable information to aid the diagnosis of fever of unknown origin (FUO), according to a new multicenter, retrospective study published in the June issue of The Journal of Nuclear Medicine. In a cohort of ...
Medical Xpress / Chemotherapy leaves detectable DNA fingerprints in childhood tumors within 18 months
Nearly half of childhood tumors treated with common types of chemotherapy showed detectable DNA changes linked to treatment within 18 months, according to a new international study led by The Hospital for Sick Children (SickKids). ...
Medical Xpress / Gene regulation map reveals treatment targets for heart failure
Researchers from the University of California San Diego have created the most detailed map to date of how gene regulation breaks down in human heart failure, revealing how genes are controlled in specific cell types as the ...
Medical Xpress / How systemic immune regulation is 'hijacked' during tumor progression
The immune system plays a critical role in protecting the body from cancer by recognizing and eliminating abnormal cells before they can develop into tumors. This process relies on T cells that can recognize tumor-derived ...
Medical Xpress / From urinary tract infection to brain abscess: How bacterial subpopulations can spread to distant body sites
Researchers from the University of Cologne, the German Center for Infection Research (DZIF), and the Broad Institute of Harvard and MIT present a clinical case in the New England Journal of Medicine that provides new insights ...
Medical Xpress / Children with severe pneumonia can leave hospital sooner after switching to oral antibiotics, trial shows
Children hospitalized with severe pneumonia can safely switch from injectable to oral antibiotics once they begin to recover, allowing many to return home sooner and complete treatment outside the hospital. That is according ...
