Medical Xpress news
Medical Xpress / Pakistani genomes reveal 34,000 knockouts that could explain why mouse-based drugs fail in humans
A comprehensive analysis of 173,303 genomes from Pakistan, published today in Nature, is upending how scientists understand human genetics and drug development. By identifying 34,000 people who are "human knockouts," with ...
Medical Xpress / Integrated trauma therapy found to be effective for people with co-occurring psychosis and PTSD
New research from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King's College London, published in The Lancet Psychiatry, has found that people with psychosis experiencing post-traumatic stress disorder ...
Medical Xpress / Inhibiting high levels of leukemia ABCD1 protein with jojoba could lead to new treatment option
University of Guelph research published in the journal publication Blood has uncovered a surprising weakness in acute myeloid leukemia (AML) that a compound in a common skin care ingredient may be able to target.
Medical Xpress / Multilingual benchmark evaluates how well AI interprets clinical text and health records in nine languages
Researchers at Mass General Brigham recently developed BRIDGE, a multilingual benchmark that evaluates how well large language models (LLMs) understand clinical patient care text, including language used in electronic health ...
Medical Xpress / AI model proves to be a heavyweight in tumor assessment: Mesothelioma patients and physicians benefit
Physicians and researchers at the Netherlands Cancer Institute have developed an AI model that outperforms physicians in evaluating treatment response in pleural mesothelioma. Far more accurate than the current international ...
Medical Xpress / Amyloid precursor protein protects neurons during nuclear waste disposal
Researchers at Niigata University's Brain Research Institute have uncovered a new function of amyloid precursor protein (APP), a molecule long studied as the precursor to amyloid-β (Aβ) in Alzheimer's disease (AD). The study ...
Medical Xpress / With neuronal data, AI models predict grammar, meaning and context of spoken sentences
By applying machine-learning models to single-cell brain recordings taken from humans in conversation, a research team identified both individual and collective neuronal activity that reflected key features of language. The ...
Medical Xpress / Study identifies a new cause of age-related inflammation, suggesting promising treatment pathway
A new study led by researchers at The University of Texas MD Anderson Cancer Center has uncovered a previously unknown connection between nucleic acid structures called R-loops and age-related inflammation—or inflammaging—that ...
Medical Xpress / Autism-related genes may share common path during early brain development
Hundreds of genes have been linked to autism, yet the precise molecular and cellular mechanisms behind it remain largely unclear. A new study published in Nature, led by Gaia Novarino at the Institute of Science and Technology ...
Medical Xpress / How a flash of light could help the brain learn new skills
A new University of Otago—Ōtākou Whakaihu Waka-led study has put its own spin on Pavlov's dog experiment, shining a light on how our brain learns new things. The study, "The superior colliculus gates dopamine responses to ...
Medical Xpress / An experimental molecule 'reprograms' the brain's defenses against Alzheimer's disease
A team has identified an experimental molecule capable of "reprogramming" the brain's immune cells to restore part of their protective function against Alzheimer's disease. The study, published in the journal Cell Death and ...
Medical Xpress / Exploiting a common weakness in enzymes could lead to a single vaccine against diarrhea-causing gut pathogens
The bacteria enterotoxigenic E. coli and Shigella together cause hundreds of millions of infections each year and are among the leading causes of diarrheal death, especially in children. Decades of vaccine development efforts ...
