Medical Xpress news

Medical Xpress / Single-dose base editing corrects PKD1 mutation and extends survival in ADPKD preclinical models

Mayo Clinic researchers have developed a promising gene-editing therapy that directly corrects a genetic mutation responsible for autosomal dominant polycystic kidney disease (ADPKD), the most common inherited kidney disorder.

Jan 29, 2026 in Genetics
Medical Xpress / Why a potential vaccine for neonatal sepsis faces challenges ahead

A major international study has assessed key bacterial targets that could form the basis of a new maternal vaccine to protect newborns from life-threatening infections. The University of Strathclyde contributed analytical ...

Jan 29, 2026 in Pediatrics
Medical Xpress / In schizophrenia, altered oral microbiome may signal cognitive impairment

An association between oral microbiota and cognitive performance in schizophrenia has been reported by researchers at Science Tokyo. By analyzing saliva samples and cognitive test scores from patients with schizophrenia and ...

Jan 29, 2026 in Psychology & Psychiatry
Medical Xpress / Social robot with AI shows promise for patient and clinician acceptance

Researchers from the University of Twente, MST and Politecnico di Milano conducted a pilot study to explore whether a GPT-controlled social robot can support patients with medical information in a hospital setting. The first ...

Jan 29, 2026 in Health
Medical Xpress / Half of trans people pay for gender affirming surgery themselves

One in three people in Norway (32.5%) who have started hormone treatment, and half (49.5%) of those who have undergone gender affirming surgery, have obtained treatment entirely through private funding. That is the findings ...

Jan 29, 2026 in Surgery
Medical Xpress / Nearly half of American adults will be obese by 2035, study warns

Nearly half of American adults—some 126 million people—will be obese within 10 years, a new study projects.

Jan 29, 2026 in Health
Medical Xpress / Immunotherapy before surgery helps shrink tumors in patients with desmoplastic melanoma

New results from a clinical trial co-led by UCLA investigators demonstrate how treating desmoplastic melanoma, a rare and aggressive skin cancer, with immunotherapy before surgery can dramatically shrink or even eliminate ...

Jan 29, 2026 in Immunology
Medical Xpress / Parental firearm injury linked to increased mental health burden in children

Each year, 20,000 children and adolescents across the U.S. lose a parent to gun violence, while an estimated two to three times more have a parent who has been injured due to a firearm. To better understand the mental health ...

Jan 28, 2026 in Psychology & Psychiatry
Medical Xpress / Smart speaker may improve mental health and blood sugar levels for seniors with type 2 diabetes

A simple smart speaker may be the latest tool to help seniors with some of the mental and physical challenges of type 2 diabetes. A new study published in JAMA Network Open reports that using an Amazon Echo Dot helped reduce ...

Jan 28, 2026 in Diabetes
Medical Xpress / Berberine shows no advantage over placebo for reducing liver and belly fat

A multicenter research effort in China conducted clinical trial testing of oral berberine for six months in diabetes-free adults with obesity and metabolic dysfunction-associated steatotic liver disease. Visceral adipose ...

Jan 28, 2026 in Overweight & Obesity
Medical Xpress / New nanotherapy eases bone metastasis pain by disrupting tumor-nerve crosstalk

A new nano-sized drug carrier that finds bone tumors and releases treatment exactly where it's needed is here to improve the precision and comfort of cancer therapy. Designed by a team of researchers from China, this smart ...

Jan 28, 2026 in Medical research
Medical Xpress / Neuron position found less crucial for brain connectivity than once thought

The human brain contains billions of connected neurons that collectively support different mental functions, including the processing of sensory information, the encoding of memories, attention processes, and decision-making. ...

Jan 28, 2026 in Neuroscience