Medical Xpress news

Medical Xpress / Gene therapy halts progression of rare genetic condition in young boy

When Michael Pirovolakis received an individualized gene therapy in a single-patient clinical trial at The Hospital for Sick Children (SickKids) in March 2022, the course of his condition was dramatically altered.

Jun 28, 2024 in Genetics
Medical Xpress / Researchers find brains can tune their navigation system without landmarks

Johns Hopkins research sheds new light on how mammals track their position and orientation while moving, revealing that visual motion cues alone allow the brain to adjust and recalibrate its internal map even in the absence ...

Jun 28, 2024 in Neuroscience
Medical Xpress / Two groups of neurons linked to feeling full identified—one for before-meal fullness and one for after-meal fullness

A team of biomedical researchers from the U.S. and the U.K. has identified two groups of neurons that take part in the process of feeling full—one before eating and one after. In their study, published in the journal Science, ...

Jun 28, 2024 in Medications
Medical Xpress / Study reveals significant differences in RNA editing between postmortem and living human brain

Researchers from the Icahn School of Medicine at Mount Sinai have shed valuable light on the nuanced functions and intricate regulatory methods of RNA editing, a critical mechanism underlying brain development and disease.

Jun 28, 2024 in Genetics
Medical Xpress / Protein maps created using scanning technology on cerebrospinal fluid to find markers for Alzheimer's

A large team of neuroscientists, biochemists and Alzheimer's specialists affiliated with institutions in the U.S. and Iceland has created a protein map to look for patterns in cerebrospinal fluid that may serve as markers ...

Jun 28, 2024 in Neuroscience
Medical Xpress / A dog's puppyhood can cause 'puppy blues' reminiscent of baby blues

Bringing a puppy home is usually a happy event, but sometimes the life change that comes with it can provoke significant negative emotions. In a study now published in npj Mental Health Research, researchers found that almost ...

Jun 28, 2024 in Psychology & Psychiatry
Medical Xpress / Loss of salt and body fluid stimulates kidney regeneration in mice

A loss of salt and body fluid can stimulate kidney regeneration and repair in mice, according to a new study led by USC Stem Cell scientist Janos Peti-Peterdi and published in the Journal of Clinical Investigation.

Jun 28, 2024 in Medical research
Medical Xpress / Researchers discover molecule's ability to suppress negative effects of type 2 diabetes, obesity

Researchers from Children's Hospital of Philadelphia (CHOP) revealed the mechanisms behind one particular molecule's involvement in regulating insulin sensitivity. The findings, which were translated from a preclinical animal ...

Jun 28, 2024 in Diabetes
Medical Xpress / Study reveals why AI models that analyze medical images can be biased

Artificial intelligence models often play a role in medical diagnoses, especially when it comes to analyzing images such as X-rays. However, studies have found that these models don't always perform well across all demographic ...

Jun 28, 2024 in Health informatics
Medical Xpress / Study suggests changing the gut microbiome improves health outcomes for newly-diagnosed metastatic kidney cancer

Physician scientists from City of Hope, one of the largest cancer research and treatment organizations in the United States, found that people with metastatic kidney cancer who orally took a live biotherapeutic product called ...

Jun 28, 2024 in Oncology & Cancer
Medical Xpress / Chemical conjugation mitigates immunotoxicity of chemotherapy of lipid nanoparticles

While chemotherapy can stimulate antitumor immunity, it may also impair immune cell function and induce lymphodepletion, reducing the effectiveness of subsequent immunotherapy. Thus, nanoparticle-based drug delivery systems ...

Jun 28, 2024 in Medical research
Medical Xpress / Tissue bridges as predictors of recovery from cervical spine injuries

Results of the longitudinal study, "Prognostic value of tissue bridges in cervical spinal cord injury," have the potential to change clinical practice. They have been published in The Lancet Neurology.

Jun 28, 2024 in Neuroscience