Medical Xpress news

Medical Xpress / Scientists complete first drafts of developing mammalian brain cell atlases

A global consortium of scientists has created the first and most detailed "developmental maps" of the mammalian brain (from mouse to human) to date, taking the first critical steps in unraveling the mystery of early brain ...

Nov 5, 2025 in Medical research
Medical Xpress / Therapeutic brain implants that travel through blood defy the need for surgery

What if clinicians could place tiny electronic chips in the brain that electrically stimulate a precise target, through a simple injection in the arm? This may someday help treat deadly or debilitating brain diseases, while ...

Nov 5, 2025 in Neuroscience
Medical Xpress / How brain lipids help neurons communicate and protect themselves

A University of Alberta research team has discovered a new function for brain molecules known as gangliosides, offering potential new targets for the treatment of Huntington's and other genetic neurological diseases.

Nov 5, 2025 in Neuroscience
Medical Xpress / Brain pathway may fuel both aggression and self-harm

Aggression and self-harm often co-occur in individuals with a history of early-life trauma—a connection that has largely been documented by self-reporting in research and clinical settings. Adding to this connection, individuals ...

Nov 5, 2025 in Psychology & Psychiatry
Medical Xpress / Imaging technique maps the brain's nerve fiber labyrinth with micrometer precision

In order to understand brain diseases, neuroscientists try to untangle the intricate nerve fiber labyrinth of our brain. Before analyzing brain tissue under a microscope, it is often soaked in paraffin wax to achieve high-quality ...

Nov 5, 2025 in Neuroscience
Medical Xpress / Macrophage 'bodyguard' disruptors may help overcome hormone-resistant breast cancer

In preclinical studies, researchers at Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine, have tested a new combination therapy for hormone-resistant, estrogen receptor-positive ...

Nov 5, 2025 in Oncology & Cancer
Medical Xpress / Experimental drug blocks key protein to trigger cancer cell self-destruction in lung tumors

NYU Langone Health researchers found that a type of cell death caused by a buildup of highly reactive molecules suppresses lung tumor growth.

Nov 5, 2025 in Oncology & Cancer
Medical Xpress / Abnormal repetitive behaviors in mice are associated with oxidative stress

Abnormal repetitive behaviors in mice are strongly linked to multiple biomarkers of oxidative stress, which occurs when antioxidants cannot counteract the effects of harmful molecules in the body, according to a study published ...

Nov 5, 2025 in Psychology & Psychiatry
Medical Xpress / Two main gene discovery methods reveal complementary aspects of biology

The two main approaches for discovering disease genes reveal distinct aspects of biology, a new study shows. While both methods are widely used, the research found that they identify different genes with major implications ...

Nov 5, 2025 in Genetics
Medical Xpress / Triggering cell death in metastatic melanoma may pave the way for new cancer treatments

Metastatic melanoma cells that have spread to lymph nodes survive by relying on a protein called ferroptosis suppressor protein 1 (FSP1)—a surprising metabolic dependency that could open the door to a new class of cancer ...

Nov 5, 2025 in Oncology & Cancer
Medical Xpress / Large-scale protein screen reveals targets for a new tuberculosis vaccine

A large-scale screen of tuberculosis proteins has revealed several possible antigens that could be developed as a new vaccine for TB, the world's deadliest infectious disease.

Medical Xpress / CRISPR screen identifies new regulator of androgen receptor in prostate cancer

A poorly characterized protein, historically thought to be a chaperon or enzyme, may actually be a key player in prostate cancer. In a systematic CRISPR screen, scientists from Arc Institute, UCSF, and the Fred Hutchinson ...

Nov 5, 2025 in Oncology & Cancer