Medical Xpress news

Medical Xpress / Too sick to socialize: How the brain and immune system promote staying in bed

"I just can't make it tonight. You have fun without me." Across much of the animal kingdom, when infection strikes, social contact shuts down. A new study details how the immune and central nervous systems implement this ...

Nov 25, 2025 in Neuroscience
Medical Xpress / Shapeshifting tumors unmasked: New insights into master regulators reveal therapeutic vulnerabilities

Some tumors are almost impossible to treat. That's especially true for carcinomas, which don't behave like other malignancies. Some of these tumors act as shapeshifters and start to resemble cells from other organs of the ...

Nov 25, 2025 in Oncology & Cancer
Medical Xpress / Calcium-sensitive switch boosts the efficacy of cancer drugs

Cancer-fighting antibody drugs are designed to penetrate tumor cells and release a lethal payload deep within, but too often they don't make it that far. A new study shows how this Trojan Horse strategy works better by exploiting ...

Nov 25, 2025 in Medications
Medical Xpress / Long-term calorie restriction may slow normal brain aging

As the brain ages, cells in the central nervous system experience metabolic dysfunction and increased oxidative damage. These cellular issues impair the ability to maintain the myelin sheath (the protective covering around ...

Nov 25, 2025 in Neuroscience
Medical Xpress / Shape of your behind may signal diabetes

The shape of the gluteus maximus muscle in the buttocks changes in different ways with aging, lifestyle, frailty, osteoporosis and type 2 diabetes, and these changes differ between women and men, according to new research ...

Nov 25, 2025 in Diabetes
Medical Xpress / Evaluating the effectiveness of a state-level SNAP incentive program

When Eat Well, Be Well was launched in Rhode Island in January 2024, it was the first program of its kind in the country to offer a financial incentive for those in the Supplemental Nutrition Assistance Program (SNAP) to ...

Nov 25, 2025 in Health
Medical Xpress / Many men may not need long-term hormone therapy for prostate cancer, study suggests

A study co-led by investigators at the UCLA Health Jonsson Comprehensive Cancer Center found that most of the benefits of androgen deprivation therapy (ADT) for prostate cancer occur within the first 9 to 12 months. Extending ...

Nov 25, 2025 in Oncology & Cancer
Medical Xpress / HER2-targeted therapy shows promising results in rare bile duct cancers

Zanidatamab, a bispecific HER2-targeted antibody, delivered clinically meaningful and durable responses for patients with HER2-positive biliary tract cancer (BTC), according to final results from the HERIZON-BTC-01 clinical ...

Nov 25, 2025 in Oncology & Cancer
Medical Xpress / Key marker linking coronary artery disease to cognitive decline identified

Individuals with coronary artery disease (CAD)—a constricting or blocking of blood vessels feeding the heart—face increased risks of strokes, cognitive impairment and dementia. However, the link between CAD and cognitive ...

Nov 25, 2025 in Cardiology
Medical Xpress / Research challenges idea that gene PTPN22 boosts production of interferons

A new paper from the University of Kansas overturns the idea that a "risk gene" carried by millions of people worldwide influences production of type 1 interferon, a workhorse of the immune system. The work is published in ...

Nov 25, 2025 in Genetics
Medical Xpress / Routine first trimester ultrasounds lead to earlier detection of fetal anomalies, finds study

Scanning for serious structural issues in fetuses during the first trimester can result in earlier detection of these issues, reports a new study led by Aris Papageorghiou at the University of Oxford, United Kingdom, published ...

Nov 25, 2025 in Obstetrics & gynaecology
Medical Xpress / Methamphetamine impairs dopamine uptake by targeting a protein modification

Dopamine brings on a surge of pleasure, but too much dopamine in a synapse can ultimately lead to mood disorders and addiction. A recent preclinical study published in The FASEB Journal suggests that methamphetamine boosts ...

Nov 25, 2025 in Neuroscience