Medical Xpress news
Medical Xpress / International project delivers hundreds of next-generation models for cancer research
Ten years and thousands of patient samples later, the National Cancer Institute (NCI) has published its results from the Human Cancer Model Initiative (HCMI) on the development of 665 organoid models of 25 types of cancer ...
Medical Xpress / Why laughter can trigger sudden muscle weakness in people with narcolepsy
Narcolepsy is a chronic neurological condition characterized by disruptions in the regulation of sleep-wake cycles. People with this condition often experience extreme sleepiness during the day and, in some cases, a sudden ...
Medical Xpress / Tumor-secreted protein makes lung vessels leakier, promoting metastasis
A protein secreted by common cancer types makes blood vessels leakier to allow metastatic tumors to form in the lungs, according to a study led by investigators at Weill Cornell Medicine and Memorial Sloan Kettering Cancer ...
Medical Xpress / Early split in brain precursors creates two neuron lineages, mouse study finds
The cerebral cortex is densely packed with different nerve cells that enable us to perceive, think and act. Yet how these cell types arise as the brain develops is still not fully understood. Irene Varela-Martínez, a postdoctoral ...
Medical Xpress / Cancer Dependency Map now includes next-generation 3D cancer models
For nearly a decade, the Cancer Dependency Map, or DepMap, at the Broad Institute has helped scientists uncover new cancer dependencies—the genetic changes some cancers need to thrive that can potentially be targeted by new ...
Medical Xpress / First-in-class small molecule inhibitor shows promise against pancreatic cancer in preclinical studies
Mayo Clinic researchers have developed an experimental drug with the help of artificial intelligence (AI) to target the "undruggable" PDZ domain of the GIPC1 protein, which helps different types of cancer, including pancreatic ...
Medical Xpress / Cancer cells hijack a fatty acid to escape immune attack in liver metastases
Liver metastases are among the most common and deadly forms of cancer spread. Now, researchers at VIB and KU Leuven, with international collaborators, have discovered how cancer cells exploit a fatty acid abundant in the ...
Medical Xpress / Dementia after age 90: Study clarifies who may be at higher risk
It may seem natural to assume that people experience cognitive decline after age 90, but until recently, researchers had limited evidence about how advanced age affects the brain. This major knowledge gap will need to be ...
Medical Xpress / How home gardens can reduce risk of type 2 diabetes
People with home gardens are less likely to develop type 2 diabetes, a University of Queensland study has found, planting fresh evidence that gardens and green spaces should be a priority in urban planning.
Medical Xpress / How 'good' bacteria from fecal transplants reduce peanut allergy
Some 33 million Americans have severe food allergies. Now, researchers at Boston Children's Hospital may have found a promising solution. In a small clinical trial, Rima Rachid, M.D., director of the Food Allergy Program ...
Medical Xpress / Immune cell dysfunction, not absence, defines skin cancer in immunosuppressed patients
Researchers at The University of Texas MD Anderson Cancer Center have discovered that immunosuppressed patients with non-melanoma skin cancer are not missing the key cancer-fighting immune cells found in immunocompetent patients, ...
Medical Xpress / Childhood physical illnesses linked to increased risk of mental health disorders in autistic young adults
Mental health conditions are more common among autistic individuals than in the general population, but knowledge about how physical and mental health interact over time has been limited. In the new study, researchers analyzed ...
