Medical Xpress news
Medical Xpress / Two unexplored Vaccinia genome regions could allow more therapeutic genes in one virus
Genetic modification of viruses has long been used as a strategy to treat and prevent different types of diseases. Specifically, it consists of exploiting certain characteristics of viruses that make them suitable tools for ...
Medical Xpress / Missing ANGPTL4 gene in mice reprograms immunity, shielding against gut inflammation
A novel study using a mouse model has found that the absence of the angiopoietin-like 4 (ANGPTL4) protein during development triggers a long-lasting reprogramming of the immune system that protects against intestinal inflammation. ...
Medical Xpress / Scientist invents super-chipped shoe to help his 89-year-old mentor avoid falling
When a big-hearted engineer noticed his 89-year-old mentor was unsteady on his feet, he sprang into action and created a futuristic shoe that could in the future help him—and scores of other older people—keep their balance. ...
Medical Xpress / Encapsulated ovarian donor tissue restores natural hormone cycles in mice
With the aim of restoring female hormone cycles for pediatric cancer survivors, a team of University of Michigan researchers has demonstrated that donated ovarian tissue, hidden from the immune system in a capsule, can produce ...
Medical Xpress / Vascularized liver tissueoid-on-a-chip models regeneration and transplant rejection
Dr. Vadim Jucaud's lab at the Terasaki Institute has developed a vascularized liver tissueoid-on-a-chip (LToC) platform that recapitulates key structural, functional, and immunological features of human liver tissue, enabling ...
Medical Xpress / Aortic stenosis: 200 newly identified genes raise hope for future treatments
A new study on aortic stenosis, the most common form of heart valve disease, has identified more than 200 new genes that predispose individuals to this condition, for which no treatment currently exists. The discovery of ...
Medical Xpress / Docetaxel rechallenge linked to longer survival than cabazitaxel, study suggests
A common clinical question for medical oncologists treating metastatic castration-resistant prostate cancer is, should patients who previously received docetaxel and progress on it, reuse docetaxel or switch to cabazitaxel ...
Medical Xpress / Largest study of rare skin cancer in Mexican patients shows that it is more complex than previously thought
Genetic ancestry may play a key role in how acral melanoma, a rare and aggressive type of skin cancer, develops and behaves, with important implications for diagnosis and treatment, according to researchers at the Wellcome ...
Medical Xpress / KRAS mutation type may guide more effective cancer treatments
KRAS is the most frequently mutated oncogene across all human cancers. Although different KRAS mutations have long been thought to exert the same cancer-driving effects, a new study led by UT Southwestern Medical Center researchers ...
Medical Xpress / A single sample classifier can predict cancer-associated fibroblast subtypes in patient samples
In a collaboration between several labs at UNC Lineberger, researchers have defined cancer-associated fibroblast (CAF) subtypes that are clinically robust, prognostic, and predictive of immunotherapy response and developed ...
Medical Xpress / Vaccine shows protection against severe childhood diarrhea
Each year, tens of thousands of children under 5 die from diarrheal disease caused by enterotoxigenic Escherichia coli (ETEC), primarily in low-income countries. A new ETEC vaccine has shown promising results in reducing ...
Medical Xpress / Study reveals how children with disruptive behavior get 'stuck' in specific brain states
Youth with related behavior challenges may have trouble moving between different brain states, according to a new study from Yale Child Study Center. Their brains appear to get stuck in states with disrupted connections in ...
