Medical Xpress news

Medical Xpress / Two wrongs make a right: How two damaging disease variants can restore health

Scientists at Pacific Northwest Research Institute (PNRI) have overturned a long-held belief in genetics: that inheriting two harmful variants of the same gene always worsens disease. Instead, the team found that in many ...

Jan 12, 2026 in Genetics
Medical Xpress / T cells gain superior memory through new reprogramming method, boosting cancer-fighting abilities

Georgetown University's Lombardi Comprehensive Cancer Center researchers have identified a new way to reprogram T cells, which are infection and tumor-fighting white blood cells, so that they have a superior memory, thereby ...

Jan 12, 2026 in Oncology & Cancer
Medical Xpress / Autologous T cell therapy targeting multiple antigens shows promise in treating pancreatic cancer

A recent publication in Nature Medicine describes a novel immunotherapy targeting pancreatic cancer that has shown promising results in a first in-human phase 1/2 trial.

Jan 12, 2026 in Oncology & Cancer
Medical Xpress / Using rare sugars to address alcoholism

While investigating the FGF21-oxytocin-dopamine system, a mechanism that regulates sugar appetite, a team of researchers at Kyoto University noticed reports suggesting that the protein FGF21 may regulate alcohol ingestion.

Jan 12, 2026 in Neuroscience
Medical Xpress / Genes that predispose an individual to pancreatic cancer identified

A new study by the National Cancer Research Center (CNIO) has identified several sets of genes related to the predisposition to develop pancreatic ductal adenocarcinoma (the most common type of pancreatic cancer), as well ...

Jan 12, 2026 in Oncology & Cancer
Medical Xpress / How brain waves shape our sense of self

A new study from Karolinska Institutet, published in Nature Communications, reveals how rhythmic brain waves known as alpha oscillations help us distinguish between our own body and the external world. The findings offer ...

Jan 12, 2026 in Psychology & Psychiatry
Medical Xpress / How weight loss benefits the health of your fat tissue

It is well known that obesity typically leads to inflammation and dysfunction of fat tissue that increases the risk of developing metabolic diseases such as diabetes and cardiovascular diseases.

Jan 12, 2026 in Overweight & Obesity
Medical Xpress / Higher daylight exposure improves cognitive performance, study finds

A real world study led by University of Manchester neuroscientists has shown that higher daytime light exposure positively influences different aspects of cognition.

Jan 12, 2026 in Psychology & Psychiatry
Medical Xpress / One in four older Americans with dementia prescribed risky brain-altering drugs despite safety warnings

Despite years of clinical guidelines warning against the practice, one in four Medicare beneficiaries with dementia is prescribed brain-altering medications linked to falls, confusion, and hospitalization, according to new ...

Dialog / Scientists report new immune insights and targets into LRRK2 mutations in Parkinson's disease

Parkinson's disease (PD) is a debilitating and progressive neurodegenerative disorder caused by the loss of dopamine-producing neurons in the substantia nigra, a brain region essential for motor control. Clinically, it is ...

Jan 12, 2026 in Genetics
Medical Xpress / Little-known enzyme could supercharge immune cells to tackle cancer

Supercharging immune cells could provide an effective way to tackle cancer, according to new research by scientists in Scotland.

Jan 12, 2026 in Oncology & Cancer
Medical Xpress / Mechanism behind persistent autoimmune joint destruction revealed in new study

Nearly 1.5 million Americans and nearly 5% of women over the age of 55 have rheumatoid arthritis (RA), an incurable autoimmune disease marked by joint inflammation and subsequent damage. Despite advances in treatment, such ...

Jan 12, 2026 in Arthritis & Rheumatism