Medical Xpress news
Medical Xpress / Two unexplored Vaccinia genome regions could allow more therapeutic genes in one virus
Genetic modification of viruses has long been used as a strategy to treat and prevent different types of diseases. Specifically, it consists of exploiting certain characteristics of viruses that make them suitable tools for ...
Medical Xpress / KRAS mutation type may guide more effective cancer treatments
KRAS is the most frequently mutated oncogene across all human cancers. Although different KRAS mutations have long been thought to exert the same cancer-driving effects, a new study led by UT Southwestern Medical Center researchers ...
Medical Xpress / Aortic stenosis: 200 newly identified genes raise hope for future treatments
A new study on aortic stenosis, the most common form of heart valve disease, has identified more than 200 new genes that predispose individuals to this condition, for which no treatment currently exists. The discovery of ...
Medical Xpress / Largest study of rare skin cancer in Mexican patients shows that it is more complex than previously thought
Genetic ancestry may play a key role in how acral melanoma, a rare and aggressive type of skin cancer, develops and behaves, with important implications for diagnosis and treatment, according to researchers at the Wellcome ...
Medical Xpress / Vascularized liver tissueoid-on-a-chip models regeneration and transplant rejection
Dr. Vadim Jucaud's lab at the Terasaki Institute has developed a vascularized liver tissueoid-on-a-chip (LToC) platform that recapitulates key structural, functional, and immunological features of human liver tissue, enabling ...
Medical Xpress / Docetaxel rechallenge linked to longer survival than cabazitaxel, study suggests
A common clinical question for medical oncologists treating metastatic castration-resistant prostate cancer is, should patients who previously received docetaxel and progress on it, reuse docetaxel or switch to cabazitaxel ...
Medical Xpress / Vaccine shows protection against severe childhood diarrhea
Each year, tens of thousands of children under 5 die from diarrheal disease caused by enterotoxigenic Escherichia coli (ETEC), primarily in low-income countries. A new ETEC vaccine has shown promising results in reducing ...
Medical Xpress / Encapsulated ovarian donor tissue restores natural hormone cycles in mice
With the aim of restoring female hormone cycles for pediatric cancer survivors, a team of University of Michigan researchers has demonstrated that donated ovarian tissue, hidden from the immune system in a capsule, can produce ...
Medical Xpress / Machine-learned biomarker identifies those at high risk for liver cancer
Researchers led by Xian-Yang Qin at the RIKEN Center for Integrative Medical Sciences (IMS) in Japan have developed a score that predicts the risk of liver cancer. Published in the journal Proceedings of the National Academy ...
Medical Xpress / A single sample classifier can predict cancer-associated fibroblast subtypes in patient samples
In a collaboration between several labs at UNC Lineberger, researchers have defined cancer-associated fibroblast (CAF) subtypes that are clinically robust, prognostic, and predictive of immunotherapy response and developed ...
Medical Xpress / A potential new lymphedema target: Clearing cholesterol deposits to reduce swelling
An international team led by National University of Singapore researchers has linked secondary lymphedema to excessive cholesterol buildup inside skin and around lymphatic vessels. Excess cholesterol deposition tracked with ...
Medical Xpress / Mint, eucalyptus and chili compounds reveal powerful synergy against inflammation in immune cells
Many everyday foods and seasonings—such as herbs, spices, and aromatic plants—contain natural compounds called phytochemicals that can regulate inflammatory pathways. For centuries, these ingredients have been used together ...
