Medical Xpress news
Medical Xpress / New dual-target drug may help overcome immunotherapy resistance in pancreatic cancer
Pancreatic ductal adenocarcinoma is one of the deadliest cancer types, with a five-year survival rate of 13%. There are only two treatment regimens available with limited efficacy. Pancreatic cancers do not respond to immunotherapy ...
Medical Xpress / Molecular switch guides neurons through developing brain, revealing opposing migration pathways
During brain development, neurons can regulate their movement until they reach their final destination thanks to a "molecular switch" involving the protein Teneurin 4 (Ten4). This protein can guide neuronal migration through ...
Medical Xpress / Magic tricks can reduce stress, pain and anxiety for children during vaccinations
Injections can be a source of stress and anxiety for children. The Willem-Alexander Children's Hospital is exploring ways to improve the experience. Together with illusionist Victor Mids and researchers from Leiden, they ...
Medical Xpress / Nerves in skin can slow melanoma growth
Nerve fibers within melanomas can slow their growth, according to a study led by Weill Cornell Medicine investigators. The findings help clarify the emerging field of cancer neuroscience and may inform future therapeutic ...
Medical Xpress / Why CAR T therapy works for some patients but fails for others may be getting clearer
Chimeric antigen receptor (CAR) T-cell therapy is one of oncology's most powerful ideas: Harvest a cancer patient's own immune cells, genetically engineer them to recognize tumor cells, multiply them in a laboratory and reinject ...
Medical Xpress / AI model could warn of cardiac arrest 10 to 15 minutes early
Perelman School of Medicine cardiologist Rajat Deo has been studying electrocardiographic (ECG) data and cardiac rhythms for nearly two decades at Penn. He says that every second, hospitals generate "enormous streams of ECG ...
Medical Xpress / Revealing the unusual ability of a protein involved in lung and thyroid cancer
Research conducted at the National Cancer Research Centre (CNIO) has revealed an unexpected behavior observed in a protein involved in several types of cancer: it manages to self-activate, meaning it gives itself the order ...
Medical Xpress / Preclinical efficacy of experimental peptide therapy suggests a new target for metastatic breast cancer treatments
A peptide that successfully targeted and killed metastatic cancer cells in mice may open the door to developing more efficient ways to detect and treat metastatic breast cancer in humans, UTHealth Houston researchers have ...
Medical Xpress / Tumor-on-a-chip reveals how pancreatic cancer interacts with scar tissue and resists treatment
Pancreatic cancer remains one of the most difficult cancers to treat, in large part because tumors do not exist in isolation. Instead, they are surrounded by a dense and complex network of blood vessels, connective tissue, ...
Medical Xpress / Choosing safer diabetes medications for older adults
Older adults with type 2 diabetes face a difficult trade-off: they are among the most vulnerable to medication-related harms yet are often underrepresented in the clinical trials that guide treatment decisions. A new study ...
Medical Xpress / Tumor bacteria inspire peptide that starves prostate cancer cells in preclinical tests
Researchers at the University of Illinois Chicago have developed an anti-cancer therapy inspired by bacteria found in cancer tumors. When tested in combination with radiation in animal models of prostate cancer, it was highly ...
Medical Xpress / Sedatives in pregnancy not linked to psychiatric disorders in children
A large South Korean study published by The BMJ finds no increased risk of psychiatric or neurodevelopmental disorders, such as ADHD and autism, in children whose mothers used sedative drugs (benzodiazepines or Z-hypnotics) ...
