Medical Xpress news
Medical Xpress / Oral small-molecule GLP-1 drugs penetrate deep into the brain to suppress cravings
A study has found that an emerging class of GLP-1 weight-loss drugs suppresses eating for pleasure, or hedonic feeding, in mice by modulating a reward circuit deep within the brain. This newly charted pathway—separate from ...
Medical Xpress / At-home blood test and brain testing could screen people for dementia risk
A finger prick blood test combined with online brain testing—all done from home—could one day effectively identify people's risk of developing dementia, according to a new study.
Medical Xpress / Direct-to-proteasome strategy degrades two cancer proteins and may curb drug resistance
A preclinical study has developed a strategy that enables the forced elimination of proteins that help tumors survive chemotherapy. This finding opens a new avenue to tackle resistance to cancer treatments, one of the major ...
Medical Xpress / AI screening tool gives pathologists 'spatial super vision' to detect hidden cancer
QIMR Berghofer scientists have developed an AI screening tool that harnesses the power of cutting-edge spatial biology analysis to give pathologists "super vision" to detect hidden genetic markers of cancer in standard patient ...
Medical Xpress / One overlooked detail in cancer genomes is rewriting which mutations really matter
It's a fundamental principle of science: Correlation does not equal causation. Every cancer cell has genetic mutations, but not all of those mutations necessarily drive the cancer.
Medical Xpress / Why zebrafish hearts heal so well: Early immune signals can improve repair even further
When the human heart is damaged by a heart attack, stiff scar tissue eventually forms around the affected areas. This weakens the heart's pumping ability and increases the risk of heart failure and arrhythmias. Zebrafish, ...
Medical Xpress / How HIV hijacks a cellular 'gateway' to infect resting immune cells
Researchers from Queen Mary University of London have uncovered a previously unknown mechanism by which HIV-1 can infect resting immune cells. The discovery challenges a decades-old assumption in HIV biology, and opens new ...
Medical Xpress / Hidden reservoir may drive brain cancer relapse in 65% of patients
All types of brain cancers collectively have a five-year survival rate of just 33%, according to the National Cancer Institute's Surveillance, Epidemiology, and End Results Program. For a type of brain cancer called glioblastoma, ...
Medical Xpress / Can AI forecast immune responses? New benchmark shows where predictions hold up and fail
Artificial intelligence is increasingly being used to help scientists accelerate drug discovery and search for new treatments. But for AI tools to work effectively, researchers need to know whether they can be validated and ...
Medical Xpress / Fish reveal four distinct sleep states, including three with eye movements
Humans and other mammals cycle through distinct sleep phases. One of them is easily recognized by the darting motion of the eyes behind closed lids, giving it its name: REM (rapid eye movement) sleep. This is the state in ...
Medical Xpress / RNA blood markers may reveal illness trajectory and treatment success within days
Scientists are developing a test which could one day be used to predict how a patient's illness will progress, and even how well they will respond to treatment. The international team, led by researchers at Imperial College ...
Medical Xpress / Controlled peanut intake may reduce allergies in toddlers
Researchers at Karolinska Institutet have successfully treated children aged 1–3 years with peanut allergies. The children slowly became accustomed to eating peanuts by consuming small amounts of them daily, which were gradually ...