Medical Xpress news
Medical Xpress / Experimental treatment directly kills prostate tumor cells while reawakening antitumor immunity
Prostate-targeted, engineered nanoparticles made of amorphous silica are effective in killing prostate tumors directly while enhancing antitumor immunity, according to a preclinical study led by investigators at Weill Cornell ...
Medical Xpress / AI deciphers how fast ALS progresses and which functions decline first
ALS (amyotrophic lateral sclerosis) is a fatal neurodegenerative disease that gradually affects a person's ability to move, speak and breathe. It advances differently in every patient. Now, researchers at Nagoya University ...
Medical Xpress / Mitochondria reveal new TDP-43 signaling route tied to ALS and dementia
A new study published in Nature Communications has uncovered a communication pathway between mitochondria and RNA granules that may help scientists understand how the toxic buildup of the TDP-43 protein leads to the development ...
Medical Xpress / Combo treatment delays multiple myeloma progression and may improve survival, study finds
Patients with multiple myeloma who received a new immunotherapy combination lived significantly longer without their cancer worsening and showed early signs of improved survival in a large international clinical trial.
Medical Xpress / Inside failing joints: How wear and corrosion reshape hip and knee implants over time
Orthopedic implants are designed to restore movement and relieve pain, offering patients a second or even third chance at mobility. A hip or knee replacement is often framed as a durable fix, engineered to last for years, ...
Medical Xpress / How wastewater could spot hidden HIV burden in communities before clinics do
Human immunodeficiency virus 1 (HIV-1) detection in wastewater offers a novel approach to monitor the virus in communities. Baylor College of Medicine researchers and colleagues at collaborating institutions report in Nature ...
Medical Xpress / Gene therapy prolongs health span and preserves the function of multiple organs in mice during aging
A research team from the Universitat Autònoma de Barcelona (UAB) has shown that a one-time administration of a gene therapy expressing the metabolic factor FGF21 can prolong health span in old mice. The 27-month pharmacology ...
Medical Xpress / Anti-inflammatory molecule shows potential against Parkinson's in murine study
Researchers at the Federal University of São Paulo (UNIFESP) in Brazil have discovered a new strategy that may protect neurons and other brain cells involved in Parkinson's disease in the future. The results of the study, ...
Medical Xpress / Silicon-slide imaging could speed cancer diagnosis with 99% agreement, no dyes needed
Scientists at King Abdullah University of Science and Technology (KAUST) have developed a new stain-free imaging platform designed to analyze tissue samples more quickly and consistently, supporting future AI-assisted cancer ...
Medical Xpress / Target with potential to improve CAR T-cell therapy response in patients with blood cancers identified
Researchers at the University of Maryland School of Medicine (UMSOM) have identified a target that may improve the response to CAR T-cell therapy, a treatment for patients with recurrent or difficult-to-treat blood cancers.
Medical Xpress / Asthma attacks reshape airway tissue through mechanical stress, lung-on-a-chip reveals
About 25 million people in the U.S.—roughly eight out of 100—are diagnosed with asthma. Allergens, air pollution, extreme weather conditions and other irritants can cause chronic lung inflammation, leading to coughing, wheezing ...
Medical Xpress / Immune activation may determine success of dual-target CAR T therapy in glioblastoma
Dual-target CAR T-cell therapy for recurrent glioblastoma (GBM), delivered directly into the cerebrospinal fluid (CSF), triggers a broad immune response, with natural killer (NK) cell activation linked to better patient outcomes ...