Medical Xpress news
Medical Xpress / A natural molecule boosts CAR-T therapy and turns cold tumors hot
CAR-T cell therapy works well in blood cancers, but many patients still become resistant. A key reason is the presence of CAR-T regulatory T cells (CAR-Tregs), which weaken immune responses. Therefore, selectively targeting ...
Medical Xpress / Handheld TB test delivers lab-level accuracy in under 30 minutes
Drugs to treat tuberculosis have been around for more than 75 years, yet it remains the world's top infectious disease killer. A big obstacle has been testing. It's either inaccurate—missing up to half of all cases—or requires ...
Medical Xpress / Study reveals century-long cycles in US suicide rates and a long-term crisis among youth
Suicide rates in the United States follow striking, decades-long cycles likely shaped by broad social forces, according to a major new study published in the Proceedings of the National Academy of Sciences (PNAS). But beneath ...
Medical Xpress / Experiments advance efforts to restore vision with transplanted neurons
Researchers at Johns Hopkins Medicine say they have successfully demonstrated that disrupting an eye structure long suspected of blocking the growth and survival of transplanted nerve cells may help restore vision in people ...
Medical Xpress / Not all organs age alike: AI unveils the molecular impact of menopause across the female body
Despite affecting half of the world's population, menopause has historically been understudied and misunderstood, both in biomedical research and clinical practice. However, with the increase in life expectancy, the number ...
Medical Xpress / New dual-target drug may help overcome immunotherapy resistance in pancreatic cancer
Pancreatic ductal adenocarcinoma is one of the deadliest cancer types, with a five-year survival rate of 13%. There are only two treatment regimens available with limited efficacy. Pancreatic cancers do not respond to immunotherapy ...
Medical Xpress / Molecular switch guides neurons through developing brain, revealing opposing migration pathways
During brain development, neurons can regulate their movement until they reach their final destination thanks to a "molecular switch" involving the protein Teneurin 4 (Ten4). This protein can guide neuronal migration through ...
Medical Xpress / Magic tricks can reduce stress, pain and anxiety for children during vaccinations
Injections can be a source of stress and anxiety for children. The Willem-Alexander Children's Hospital is exploring ways to improve the experience. Together with illusionist Victor Mids and researchers from Leiden, they ...
Medical Xpress / Nerves in skin can slow melanoma growth
Nerve fibers within melanomas can slow their growth, according to a study led by Weill Cornell Medicine investigators. The findings help clarify the emerging field of cancer neuroscience and may inform future therapeutic ...
Medical Xpress / Why CAR T therapy works for some patients but fails for others may be getting clearer
Chimeric antigen receptor (CAR) T-cell therapy is one of oncology's most powerful ideas: Harvest a cancer patient's own immune cells, genetically engineer them to recognize tumor cells, multiply them in a laboratory and reinject ...
Medical Xpress / AI model could warn of cardiac arrest 10 to 15 minutes early
Perelman School of Medicine cardiologist Rajat Deo has been studying electrocardiographic (ECG) data and cardiac rhythms for nearly two decades at Penn. He says that every second, hospitals generate "enormous streams of ECG ...
Medical Xpress / Revealing the unusual ability of a protein involved in lung and thyroid cancer
Research conducted at the National Cancer Research Centre (CNIO) has revealed an unexpected behavior observed in a protein involved in several types of cancer: it manages to self-activate, meaning it gives itself the order ...
