Medical Xpress news
Medical Xpress / Genetic marker may flag severe IBD earlier in some patients
In the largest genetic study of inflammatory bowel disease (IBD) traits to date, researchers have identified a genetic marker associated with more severe ulcerative colitis and Crohn's disease—the major forms of IBD.
Medical Xpress / CAR T-cell therapy shows early promise in severe lupus
Early results from a UCL- and UCLH-led clinical trial suggest that a type of CAR T-cell therapy—developed by Autolus Therapeutics, a UCL spinout—could offer a new treatment approach for people with severe, treatment-resistant ...
Medical Xpress / Experimental treatment directly kills prostate tumor cells while reawakening antitumor immunity
Prostate-targeted, engineered nanoparticles made of amorphous silica are effective in killing prostate tumors directly while enhancing antitumor immunity, according to a preclinical study led by investigators at Weill Cornell ...
Medical Xpress / AI deciphers how fast ALS progresses and which functions decline first
ALS (amyotrophic lateral sclerosis) is a fatal neurodegenerative disease that gradually affects a person's ability to move, speak and breathe. It advances differently in every patient. Now, researchers at Nagoya University ...
Medical Xpress / Mitochondria reveal new TDP-43 signaling route tied to ALS and dementia
A new study published in Nature Communications has uncovered a communication pathway between mitochondria and RNA granules that may help scientists understand how the toxic buildup of the TDP-43 protein leads to the development ...
Medical Xpress / Combo treatment delays multiple myeloma progression and may improve survival, study finds
Patients with multiple myeloma who received a new immunotherapy combination lived significantly longer without their cancer worsening and showed early signs of improved survival in a large international clinical trial.
Medical Xpress / Inside failing joints: How wear and corrosion reshape hip and knee implants over time
Orthopedic implants are designed to restore movement and relieve pain, offering patients a second or even third chance at mobility. A hip or knee replacement is often framed as a durable fix, engineered to last for years, ...
Medical Xpress / How wastewater could spot hidden HIV burden in communities before clinics do
Human immunodeficiency virus 1 (HIV-1) detection in wastewater offers a novel approach to monitor the virus in communities. Baylor College of Medicine researchers and colleagues at collaborating institutions report in Nature ...
Medical Xpress / Gene therapy prolongs health span and preserves the function of multiple organs in mice during aging
A research team from the Universitat Autònoma de Barcelona (UAB) has shown that a one-time administration of a gene therapy expressing the metabolic factor FGF21 can prolong health span in old mice. The 27-month pharmacology ...
Medical Xpress / Anti-inflammatory molecule shows potential against Parkinson's in murine study
Researchers at the Federal University of São Paulo (UNIFESP) in Brazil have discovered a new strategy that may protect neurons and other brain cells involved in Parkinson's disease in the future. The results of the study, ...
Medical Xpress / Silicon-slide imaging could speed cancer diagnosis with 99% agreement, no dyes needed
Scientists at King Abdullah University of Science and Technology (KAUST) have developed a new stain-free imaging platform designed to analyze tissue samples more quickly and consistently, supporting future AI-assisted cancer ...
Medical Xpress / Target with potential to improve CAR T-cell therapy response in patients with blood cancers identified
Researchers at the University of Maryland School of Medicine (UMSOM) have identified a target that may improve the response to CAR T-cell therapy, a treatment for patients with recurrent or difficult-to-treat blood cancers.
