Medical Xpress news
Medical Xpress / Targeting the untargetable cancer—rezatapopt, an oral p53 reactivator
Memorial Sloan Kettering Cancer Center investigators and collaborators have tested rezatapopt, an oral p53 reactivator designed for tumors with TP53 Y220C, and observed antitumor activity across multiple solid tumor types ...
Medical Xpress / Painless skin patch offers new way to monitor immune health
Researchers at The Jackson Laboratory (JAX), in collaboration with the Massachusetts Institute of Technology (MIT), have developed the first bandage-like microneedle patch that can sample the body's immune responses painlessly ...
Medical Xpress / Supposedly harmless peptide may be linked to Alzheimer's disease
While companies developing drugs to treat Alzheimer's disease have spent decades and many billions of dollars targeting amyloid beta due to its role in clogging patients' brains with harmful deposits, a biochemist at the ...
Medical Xpress / AI cancer tools may rely on 'shortcut learning' rather than genuine biological signals
Artificial intelligence tools are increasingly being developed to predict cancer biology directly from microscope images, promising faster diagnoses and cheaper testing. But new research from the University of Warwick, published ...
Medical Xpress / Breast cancer still most common cancer among women worldwide, with annual cases expected to exceed 3.5 million by 2050
Despite recent advancements in breast cancer treatments, new breast cancer cases in women are predicted to rise by a third globally from 2.3 million in 2023 to more than 3.5 million in 2050. Similarly, yearly deaths from ...
Medical Xpress / Long-living wild mouse may hold secret to healthy aging
When it comes to health, some of our animal neighbors have extraordinary advantages. Ostriches, for example, are highly resistant to viruses, while sharks rarely develop cancer. And species like naked mole rats and bowhead ...
Medical Xpress / Low-dose lithium may slow verbal memory decline, exploratory clinical trial suggests
Lithium—a decades-old treatment for bipolar disorder—may hold potential neuroprotective benefits beyond mood stabilization. An exploratory clinical trial from the University of Pittsburgh suggests that low-dose oral lithium ...
Medical Xpress / New diagnostic markers for multiple sclerosis discovered in cerebrospinal fluid
Researchers from the MPI of Biochemistry and the Technical University of Munich have discovered new diagnostic markers for multiple sclerosis (MS), a disease that affects 3 million people worldwide. Using mass spectrometry, ...
Medical Xpress / A new class of Alzheimer's biomarkers: Why protein shape may beat protein levels
Researchers have identified a new type of blood-based biomarker test for Alzheimer's disease that measures structural changes in proteins, providing more information on the underlying biology of the disease than standard ...
Medical Xpress / Smart patch detects allergies before symptoms strike
A wearable device that alerts people with food allergies before a reaction begins has the potential to reduce life-threatening anaphylaxis and transform allergy management from reactive to preventive care. The AllergE patch ...
Medical Xpress / A molecular 'switch' could make pancreatic cancer more treatable
Scientists at Duke-NUS Medical School have identified a molecular "switch" that determines whether pancreatic cancer cells resist chemotherapy or respond to it—a finding that could help convert some of the most treatment-resistant ...
Medical Xpress / How dysfunctional packaging of dopamine advances symptoms of Parkinson's disease
A new study shows how dysfunctional packaging of the neurotransmitter dopamine triggers toxic processes in neurons—and how this can be repaired with simple delivery of energy (ATP). Parkinson's gradually destroys dopamine-producing ...
