Medical Xpress news
Medical Xpress / Common medicines may influence CRISPR therapy outcomes and precision cancer treatment
In a new study, scientists at the Max Planck Institute for Evolutionary Anthropology in Leipzig analyzed the impact of more than 2,000 clinically approved drugs on DNA repair and CRISPR genome editing outcomes. They found ...
Medical Xpress / How the immune system keeps mucosal fungi in check
The microbiome not only consists of bacteria, but also of fungi. Most of them support human and animal health. However, some fungi also have pathogenic potential. For instance, the yeast Candida albicans can grow in an uncontrolled ...
Medical Xpress / 'Zombie' cells spark inflammation in severe fatty liver disease, researchers find
Mayo Clinic researchers have uncovered how aging "zombie cells" trigger harmful inflammation that accelerates a severe and increasingly common form of fatty liver disease called metabolic dysfunction-associated steatohepatitis ...
Medical Xpress / Smartwatch system helps parents shorten and defuse children's severe tantrums early
Mayo Clinic researchers have developed a smartwatch-based alert system that signals parents at the earliest signs of a tantrum in children with emotional and behavioral disorders—prompting them to intervene before it intensifies.
Medical Xpress / Behavioral health spending spikes to 40% of all children's health expenditures, nearly doubling in a decade
Behavioral health care has surged to represent 40% of all medical expenditures for U.S. children in 2022, nearly doubling from 22% in 2011, according to a new study published in JAMA Pediatrics. Researchers found that pediatric ...
Medical Xpress / Neurons use simple rules to localize genetic messages, scientists discover
Scientists found that messenger RNA (mRNA) molecules that carry genetic instructions to the far reaches of neurons in the brain tend to cluster together mostly because they are abundant, not because they move in coordinated ...
Medical Xpress / RNA 'quality control' system breaks down in ALS, study finds
A Northwestern Medicine study has shed light on a critical molecular mechanism underlying amyotrophic lateral sclerosis (ALS), according to findings published in the journal Neuron.
Medical Xpress / Building a better vaccine: Flu antibodies show expanded role in preventing transmission
Today's influenza vaccines primarily prevent infection in individuals, but new research led by the University of Michigan and the Institut Pasteur suggests that incorporating antibodies generated after infection could lead ...
Medical Xpress / Cancer disrupts brain's day-night rhythm, altering stress hormone cycles in mice
"The brain is an exquisite sensor of what's going on in your body," says Cold Spring Harbor Laboratory Assistant Professor Jeremy Borniger. "But it requires balance. Neurons need to be active or inactive at the right times. ...
Medical Xpress / Accelerating drug combination discovery with machine learning
Discovering effective drug combinations may now be easier thanks to a screening platform made public today by St. Jude Children's Research Hospital scientists. Many diseases, including cancers, require combinations of drugs ...
Medical Xpress / A testing paradox: Rising sexually transmitted infections cases may mask actual decline in infections
For several years, pre-exposure prophylaxis against HIV (PrEP) has been a major success in preventing new cases. However, individuals on PrEP typically engage in riskier sexual behavior and thus are more susceptible to acquiring ...
Medical Xpress / Gene therapy for hereditary spastic paraplegia hits proof-of-principle milestone
There is no cure for the rare disease Hereditary Spastic Paraplegia (HSP), but researchers from Drexel University's College of Medicine and the UMass Chan Medical School have achieved proof-of-principle success with "silence ...
