Medical Xpress news
Medical Xpress / International project delivers hundreds of next-generation models for cancer research
Ten years and thousands of patient samples later, the National Cancer Institute (NCI) has published its results from the Human Cancer Model Initiative (HCMI) on the development of 665 organoid models of 25 types of cancer ...
Medical Xpress / Early split in brain precursors creates two neuron lineages, mouse study finds
The cerebral cortex is densely packed with different nerve cells that enable us to perceive, think and act. Yet how these cell types arise as the brain develops is still not fully understood. Irene Varela-Martínez, a postdoctoral ...
Medical Xpress / Why laughter can trigger sudden muscle weakness in people with narcolepsy
Narcolepsy is a chronic neurological condition characterized by disruptions in the regulation of sleep-wake cycles. People with this condition often experience extreme sleepiness during the day and, in some cases, a sudden ...
Medical Xpress / Cancer Dependency Map now includes next-generation 3D cancer models
For nearly a decade, the Cancer Dependency Map, or DepMap, at the Broad Institute has helped scientists uncover new cancer dependencies—the genetic changes some cancers need to thrive that can potentially be targeted by new ...
Medical Xpress / First-in-class small molecule inhibitor shows promise against pancreatic cancer in preclinical studies
Mayo Clinic researchers have developed an experimental drug with the help of artificial intelligence (AI) to target the "undruggable" PDZ domain of the GIPC1 protein, which helps different types of cancer, including pancreatic ...
Medical Xpress / Cancer cells hijack a fatty acid to escape immune attack in liver metastases
Liver metastases are among the most common and deadly forms of cancer spread. Now, researchers at VIB and KU Leuven, with international collaborators, have discovered how cancer cells exploit a fatty acid abundant in the ...
Medical Xpress / Dementia after age 90: Study clarifies who may be at higher risk
It may seem natural to assume that people experience cognitive decline after age 90, but until recently, researchers had limited evidence about how advanced age affects the brain. This major knowledge gap will need to be ...
Medical Xpress / How home gardens can reduce risk of type 2 diabetes
People with home gardens are less likely to develop type 2 diabetes, a University of Queensland study has found, planting fresh evidence that gardens and green spaces should be a priority in urban planning.
Medical Xpress / How 'good' bacteria from fecal transplants reduce peanut allergy
Some 33 million Americans have severe food allergies. Now, researchers at Boston Children's Hospital may have found a promising solution. In a small clinical trial, Rima Rachid, M.D., director of the Food Allergy Program ...
Medical Xpress / Immune cell dysfunction, not absence, defines skin cancer in immunosuppressed patients
Researchers at The University of Texas MD Anderson Cancer Center have discovered that immunosuppressed patients with non-melanoma skin cancer are not missing the key cancer-fighting immune cells found in immunocompetent patients, ...
Medical Xpress / GLP-1 drug linked to heart benefits for high-risk patients
Adding the GLP-1 receptor agonist drug tirzepatide (marketed as Mounjaro) to standard care for patients with type 2 diabetes and heart disease is associated with a lower risk of a major cardiovascular event, such as a heart ...
Medical Xpress / Most people with atypical Alzheimer's may be ineligible for new therapies
Many people with less common forms of Alzheimer's disease may not qualify for newer anti-amyloid treatments designed to slow the disease, according to a study published Aug. 5, 2026, in Neurology.
