Medical Xpress news

Medical Xpress / New HIV vaccine design trains immune system to hit shared viral target across variants

Researchers at Karolinska Institutet, in collaboration with colleagues at The Scripps Research Institute and Emory University, have developed a new vaccine strategy that has generated antibodies capable of neutralizing highly ...

Apr 29, 2026
Medical Xpress / How the architecture of the prefrontal cortex shapes our creativity

When a writer comes up with a striking metaphor, when an engineer solves a tricky problem by combining seemingly unrelated tools, or when a child invents the rules of a new game, what happens in the brain? In cognitive neuroscience, ...

Apr 29, 2026
Medical Xpress / Oxidative stress slows down the brain, but the brake can be released again

As we age, the brain undergoes various changes. Neurons function less efficiently, and key regulatory systems within the cells become unbalanced. Protein quality control, which ensures that proteins are properly processed, ...

Apr 29, 2026
Medical Xpress / Your nose may be the gateway to a stronger immune system

At the moment, an influenza vaccine called FluMist is the only licensed intranasal vaccine approved for use in humans. The vaccine is administered through a spray of fluid in the nose, rather than with an injection.

Apr 29, 2026
Medical Xpress / A natural molecule boosts CAR-T therapy and turns cold tumors hot

CAR-T cell therapy works well in blood cancers, but many patients still become resistant. A key reason is the presence of CAR-T regulatory T cells (CAR-Tregs), which weaken immune responses. Therefore, selectively targeting ...

Apr 29, 2026
Medical Xpress / Handheld TB test delivers lab-level accuracy in under 30 minutes

Drugs to treat tuberculosis have been around for more than 75 years, yet it remains the world's top infectious disease killer. A big obstacle has been testing. It's either inaccurate—missing up to half of all cases—or requires ...

Apr 29, 2026
Medical Xpress / Not all organs age alike: AI unveils the molecular impact of menopause across the female body

Despite affecting half of the world's population, menopause has historically been understudied and misunderstood, both in biomedical research and clinical practice. However, with the increase in life expectancy, the number ...

Apr 29, 2026
Medical Xpress / Study reveals century-long cycles in US suicide rates and a long-term crisis among youth

Suicide rates in the United States follow striking, decades-long cycles likely shaped by broad social forces, according to a major new study published in the Proceedings of the National Academy of Sciences (PNAS). But beneath ...

Apr 29, 2026
Medical Xpress / Experiments advance efforts to restore vision with transplanted neurons

Researchers at Johns Hopkins Medicine say they have successfully demonstrated that disrupting an eye structure long suspected of blocking the growth and survival of transplanted nerve cells may help restore vision in people ...

Apr 29, 2026
Medical Xpress / New dual-target drug may help overcome immunotherapy resistance in pancreatic cancer

Pancreatic ductal adenocarcinoma is one of the deadliest cancer types, with a five-year survival rate of 13%. There are only two treatment regimens available with limited efficacy. Pancreatic cancers do not respond to immunotherapy ...

Apr 29, 2026
Medical Xpress / Molecular switch guides neurons through developing brain, revealing opposing migration pathways

During brain development, neurons can regulate their movement until they reach their final destination thanks to a "molecular switch" involving the protein Teneurin 4 (Ten4). This protein can guide neuronal migration through ...

Apr 29, 2026
Medical Xpress / Magic tricks can reduce stress, pain and anxiety for children during vaccinations

Injections can be a source of stress and anxiety for children. The Willem-Alexander Children's Hospital is exploring ways to improve the experience. Together with illusionist Victor Mids and researchers from Leiden, they ...

Apr 29, 2026