Medical Xpress news
Medical Xpress / Scientists in France pinpoint why STING pathway hasn't been harnessed for cancer therapy yet
Deep within the cellular landscape, a quiet failure was taking place, impeding a potentially successful form of cancer treatment. For years, scientists hoped an essential part of the innate immune system that detects foreign ...
Medical Xpress / Stress proteins actively sustain joint inflammation in osteoarthritis, study finds
Why do some joints remain chronically inflamed in osteoarthritis and other rheumatic diseases? Researchers have taken an important step toward answering this question. Their findings, published in the journal Cell Death & ...
Medical Xpress / Lab-grown nerves match human sensory signal speeds, enabling tests of myelin repair
Rice University and collaborators in Switzerland have developed a platform to grow human-derived nerve cells and Schwann cells, supporting cells that form a protective coating called myelin around nerve fibers. This platform ...
Medical Xpress / LDL-cholesterol lowering medication linked to lower mortality in high-risk patients
Mass General Brigham Heart and Vascular Institute researchers have found that high-risk patients who had not previously experienced a heart attack or stroke had a lower risk of death after taking the cholesterol-lowering ...
Medical Xpress / T cell therapy shows promise in treating aggressive brain cancer
A new phase 1 clinical trial has found that an emerging immunotherapy is promising for treating recurrent glioblastoma, a highly aggressive and fatal brain cancer. Chimeric antigen receptor T (CAR-T) cell therapy is a form ...
Medical Xpress / Computer vision 'sees' our organs age at different rates
We tend to think of age as a linear progression marked by birthdays and milestones dictating when we can vote, drink, rent a car or pass beyond the crest of an arbitrary metaphorical hill. When scientists look at how organs ...
Medical Xpress / Scientists uncover microbiome signaling system that could open new paths for IBS-related constipation
Mayo Clinic researchers have discovered that chemical signals produced by gut bacteria work together to control intestinal movement. One bacterial signal helps set the intestines in motion, while another primes gut cells ...
Medical Xpress / Breast density laws linked to higher ultrasound use after mammography
More than 40% of American women ages 40 and older have dense breast tissue, according to the National Cancer Institute. This type of tissue can make cancer harder to spot on mammograms and is itself associated with a higher ...
Medical Xpress / A 'one-two punch' against aggressive breast cancer could offer an alternative to chemotherapy
Triple-negative breast cancer (TNBC) has a frustrating ability to adapt. Although this aggressive form of breast cancer can initially respond well to chemotherapy, cancer cells often find ways to survive, allowing the disease ...
Medical Xpress / Tumor 'floor plans' may predict immunotherapy response better than current biomarkers
Spatial transcriptomics is a powerful tool for creating a detailed map of not just how genes are expressed in a piece of tissue, but also where genetic activity takes place in different cells and locations within the tissue. ...
Medical Xpress / Cancer's malignant remote control: How tumors reprogram liver fat metabolism to disarm immune cells
In their quest to understand how cancers take root, grow and spread, scientists have for the past half-century explored the genetic aberrations and microenvironmental peculiarities of tumors and their constituent cells. Such ...
Medical Xpress / Each breath is linked to brain activity, offering clues to epilepsy-related breathing failures
A new study led by researchers at the University of California San Diego shows that the brain does not simply respond to breathing as a steady rhythm. Instead, the detailed shape of each individual breath is closely linked ...