Medical Xpress news
Medical Xpress / Light-activated protein triggers cancer cell death by raising alkalinity
One of the hallmarks of cancer cells is their ability to evade apoptosis, or programmed cell death, through changes in protein expression. Inducing apoptosis in cancer cells has become a major focus of novel cancer therapies, ...
Medical Xpress / Largest study of nose microbiome helps highlight those at risk of Staph aureus infection
People who persistently carry Staphylococcus aureus (S. aureus) in their nose have fewer species of other bacteria, while certain bacteria may help to prevent S. aureus colonization. These are the findings of the largest-ever ...
Medical Xpress / Stop through SPOP: Researchers develop strategy against aggressive blood cancer
When blood cancer in children progresses particularly aggressively, it is often due to a genetic defect: a gene fusion, such as the NUP98 fusion oncoprotein, which drives uncontrolled cell growth. Standard therapies are often ...
Medical Xpress / Cell nucleus shape may influence cancer treatment success
Cancer cells with a cell nucleus that is easily deformed are more sensitive to drugs that damage DNA. These are the findings of a new study by researchers at Linköping University in Sweden. The results may also explain why ...
Medical Xpress / Cancer-promoting DNA circles hitchhike on chromosomes to spread to daughter cells
Small, cancer-associated DNA circles "hitchhike" on chromosomes during cell division to spread efficiently to daughter cells by co-opting a process used to maintain cellular identity through generations, Stanford Medicine-led ...
Medical Xpress / Rising complexity in pediatric patients is reshaping hospital care
A new national analysis shows that over the past two decades, inpatient care for children with complex chronic conditions (CCCs) has become far more intensive—and is now overwhelmingly concentrated in urban teaching children's ...
Medical Xpress / Blocking Claudin-4 protein may help immune system fight aggressive ovarian cancer
Scientists at The University of Texas at El Paso have found a promising new target in the fight against high-grade serous carcinoma, an aggressive form of ovarian cancer. Less than 50% of women survive five years after diagnosis, ...
Medical Xpress / Owning a smartphone at age 12 linked to mental and physical health risks
In early adolescence, smartphone ownership is associated with depression, obesity, and insufficient sleep, according to a study published online Dec. 1 in Pediatrics.
Medical Xpress / Omomyc enhances PARP inhibitor effects and overcomes resistance in breast cancer models
Findings from a preclinical study demonstrate that Omomyc—the only direct MYC inhibitor to have successfully completed a phase I clinical trial—causes DNA damage in cancer cells which is synergistically enhanced in combination ...
Medical Xpress / Who will develop type 1 diabetes? New calculator offers quick, low-cost answers
Predicting who will develop type 1 diabetes is now cheaper and more accessible, thanks to a new tool based on research conducted at the University of Exeter which could one day help determine who to target with recently approved ...
Medical Xpress / Study warns of 'creeping catastrophe' as climate change drives a rise in infectious diseases
Infectious diseases such as malaria, dengue, and tuberculosis are considered to pose as great a challenge to global health as new or emerging pathogens, according to a major international study led by The Global Health Network ...
Medical Xpress / Oregon's first-in-the-nation hospital price cap cuts costs without compromising care
As health care costs continue to soar across the U.S., a growing number of states are setting limits on how much hospitals can charge. These policies, known as hospital payment caps, aim to curb spending by tying hospital ...