Medical Xpress news

Medical Xpress / Reducing inflammation may protect against early age-related macular degeneration-like vision loss

University of Minnesota Medical School researchers have shown that reducing chronic inflammation can significantly protect against age-related macular degeneration (AMD)-like pathology in preclinical models. The findings ...

Medical Xpress / Early brain differences may explain sex-specific risks for addiction

The roots of addiction risk may lie in how young brains function long before substance use begins, according to a new study from Weill Cornell Medicine. The investigators found that children with a family history of substance ...

Nov 21, 2025 in Neuroscience
Medical Xpress / Genetic events that can trigger leukemia in patients with a rare disorder deciphered

Two parallel and complementary studies conducted by the IDIBELL team led by Dr. Alessandra Giorgetti have succeeded in recreating models of GATA2 deficiency disease, a rare genetic disorder that affects fewer than 1 million ...

Nov 21, 2025 in Oncology & Cancer
Medical Xpress / Targeting brain immune cells could restore Alzheimer's-related lipid imbalance, research shows

More than a century ago, Alois Alzheimer noted unusual changes in brain fats, which he described as "lipoid granules," along with the buildup of amyloid‐beta (amyloid) plaques and tau protein tangles. These observations ...

Medical Xpress / Rare mutation may predict strong immunotherapy response in colorectal cancer

A new study led by researchers at The University of Texas MD Anderson Cancer Center shows that a specific subset of mutations in the POLE gene is strongly associated with durable responses to immunotherapy in patients with ...

Nov 21, 2025 in Oncology & Cancer
Medical Xpress / Arginine supplementation curbs Alzheimer's disease pathology in animal models

Alzheimer's disease (AD), a progressive neurodegenerative disorder, is one of the leading causes of dementia worldwide, and currently has no definitive cure. Although antibody-based therapies that target amyloid β (Aβ) ...

Nov 21, 2025 in Neuroscience
Medical Xpress / Experimental vaccine offers rapid, long-lasting protection against deadly tick-borne virus

Crimean-Congo hemorrhagic fever (CCHF) is one of the world's most dangerous yet overlooked infectious diseases. Spread by ticks and livestock, the virus causes sudden fever, organ failure, and internal bleeding, killing up ...

Nov 21, 2025 in Vaccination
Medical Xpress / Three times as many lung cancer deaths could be prevented with one simple step

Three times as many lung cancer deaths could be prevented if everyone eligible for screening got a chest CT scan, a new study says.

Nov 21, 2025 in Oncology & Cancer
Medical Xpress / People with diabetes or fatty liver disease found less effective at obtaining energy from ketone bodies

The liver plays a central role in storing and supplying energy to the body. In type 2 diabetes and metabolic dysfunction-associated steatotic liver disease (MASLD, commonly referred to as fatty liver disease), mitochondria—the ...

Nov 21, 2025 in Diabetes
Medical Xpress / Diagnostics for pancreatic cancer can improve with the help of AI

Pancreatic cancer is the deadliest form of cancer worldwide, mainly because the disease is often discovered late. Symptoms associated with these tumors are often non-specific, so patients and doctors do not immediately suspect ...

Nov 21, 2025 in Oncology & Cancer
Medical Xpress / Genetic risk combined with cardiovascular factors may help predict and delay dementia

Combining genetic risk with cardiovascular disease risk factors—such as high LDL cholesterol, obesity, and hypertension—may predict who is more likely to develop dementia, according to a new study led by UC San Francisco.

Nov 21, 2025 in Genetics
Medical Xpress / Study uncovers and predicts widespread molecular changes in ALS brain cells

Researchers at the University of Toronto's Temerty Faculty of Medicine have found widespread genetic and protein changes in the brain cells of people with amyotrophic lateral sclerosis (ALS), which may help shed light on ...

Nov 21, 2025 in Genetics