Medical Xpress news

Medical Xpress / Newly discovered mechanism of mitochondrial dysfunction in obesity may drive insulin resistance and type 2 diabetes
A newly discovered mechanism that leads to liver dysfunction may be a key factor in type 2 diabetes and other metabolic disorders in individuals with obesity, according to a new study led by Harvard T.H. Chan School of Public ...

Medical Xpress / Small molecule inhibitors restore normal BRAF structure, offering insight into cancer-causing mutations
Researchers led by Université de Montréal pathology and cell-biology professor Marc Therrien have identified major structural changes that enable the BRAF protein to escape control and mimic its activation, giving it strong ...

Medical Xpress / Fixing the leak: Blocking an opioid receptor for safer treatment of dopamine-related disorders
Dopamine, a small molecule derived from the amino acid tyrosine, plays a significant role in regulating multiple essential brain functions, including movement, mood and motivation as well as multiple cognitive functions, ...

Medical Xpress / Innovative immunotherapy shows promise against aggressive T cell cancers
A new type of immunotherapy that targets aggressive blood cancers shows promising results alongside manageable side effects, according to the results of an international Phase I/II clinical trial led by researchers at Washington ...

Medical Xpress / Triple therapy regimen significantly improves survival in BRAF V600E-mutated metastatic colorectal cancer
First-line treatment with the triplet combination of encorafenib, cetuximab and mFOLFOX6 significantly improved survival compared to the standard of care in patients with BRAF V600E-mutated metastatic colorectal cancer, according ...

Medical Xpress / Therapeutic target could prevent chronic gut inflammation from turning into cancer
Chronic inflammatory bowel disease is challenging to treat and carries a risk of complications, including the development of bowel cancer. Young people are particularly affected: when genetic predisposition and certain factors ...

Medical Xpress / Diagnostic tool creates stronger, longer-lasting bioluminescence signals to detect viruses
Mass General Brigham researchers are shining a powerful new light into the viral darkness with the development of Luminescence CAscade-based Sensor (LUCAS), a rapid, portable, highly-sensitive diagnostic tool for processing ...

Medical Xpress / Scientists create framework for analyzing metabolic data to predict disease risk
Statisticians from the National University of Singapore (NUS) have developed a pioneering approach for analyzing population-scale metabolomic data, marking a major advancement in the precision and depth of metabolic profiling. ...

Medical Xpress / Study shows ripple effects from World War II detainment camps on Japanese Americans' reproductive health
West Virginia University research has revealed negative intergenerational reproductive health effects from the Japanese American detainment camps of World War II.

Medical Xpress / At-home heart attacks and cardiac deaths on the rise since COVID-19 pandemic
Heart attacks are the leading cause of death globally, yet some statistics from many different countries suggest these events declined in frequency since the COVID-19 pandemic.

Medical Xpress / Researchers say malnutrition in infants 'far bigger problem than previously recognized', amid ongoing cuts
Over 10 million infants under six months old may currently be underweight, according to a new analysis of data collected across low- and middle-income countries (LMICs).

Medical Xpress / Cross-cultural analysis challenges Western-dominated understanding of autism communication
Autism spectrum disorders are associated with difficulties in social communication, long attributed to individual socio‐cognitive deficits. As a consequence of this perspective, stigma and pressure to conform to neurotypical ...