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New reporting guidelines for genetic risk prediction studies: GRIPS Statement

March 15th, 2011

This week PLoS Medicine publishes the Genetic RIsk Prediction Studies (GRIPS) Statement, a checklist and guidance to help strengthen the reporting of genetic risk prediction studies.

Because progress in gene discovery for complex diseases is fuelling interest in the application of genetic risk models for clinical and public health practice, the number of studies assessing predictive ability is steadily increasing, but the quality and completeness of reporting varies. The GRIPS Statement (and accompanying explanation document) provides guidance to enhance the transparency of study reporting, thereby improving the synthesis and application of information from multiple studies that might differ in design, conduct, or analysis.

In order to encourage dissemination, PLoS Medicine is co-publishing this article with Annals of Internal Medicine, BMJ, Circulation: Cardiovascular Genetics, European Journal of Clinical Investigation, European Journal of Epidemiology, European Journal of Human Genetics, Genetics in Medicine, Genome Medicine, and Journal of Clinical Epidemiology.

More information:
Janssens ACJW, Ioannidis JPA, van Duijn CM, Little J, Khoury MJ, et al. (2011) Strengthening the Reporting of Genetic Risk Prediction Studies: The GRIPS Statement. PLoS Med 8(3): e1000420. doi:10.1371/journal.pmed.1000420

Provided by Public Library of Science

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