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IPTi in co-endemic falciparum and vivax malaria

March 27th, 2012

A three-arm randomized trial conducted by Ivo Mueller of the Papua New Guinea Institute of Medical Research, Madang, Papua New Guinea, and colleagues among infants in Papua New Guinea estimates the preventive effect against malaria episodes of intermittent preventive treatment, in an area where children are exposed to both falciparum and vivax malaria. Their findings, published in this week's PLoS Medicine, show that intermittent preventive treatment given during infancy at the time of routine immunizations using a combination of long-lasting antimalarial drugs can effectively and safely prevent malaria in a non-African population living in a region where P. falciparum and P. vivax are both highly endemic.

More information:
Senn N, Rarau P, Stanisic DI, Robinson L, Barnadas C, et al. (2012) Intermittent Preventive Treatment for Malaria in Papua New Guinean Infants Exposed to Plasmodium falciparum and P. vivax: A Randomized Controlled Trial. PLoS Med 9(3): e1001195. doi:10.1371/journal.pmed.1001195

Provided by Public Library of Science

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