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Phys.org / CRISPR-based technique unlocks healing power of mitochondria for heart failure therapy
After a heart attack, the heart struggles to recoup and maintain energy. One-third of patients develop heart failure as a result—a condition that impacts 6.8 million Americans and carries a high lifetime risk, with 1 in ...
Phys.org / AI tool streamlines drug synthesis, dramatically reducing lab work and costs
Drug discovery is like molecular Tetris. Chemists snap atoms together, adjusting the pieces until everything fits, and suddenly, a molecule makes a promising new medicine. Normally, creating better molecules consumes huge ...
Phys.org / Deep ocean microbes may already be prepared to tackle climate change
Deep-sea waters are warming due to heat waves and climate change, and it could spell trouble for the oceans' delicate chemical and biological balance. However, a study published in Proceedings of the National Academy of Sciences ...
Phys.org / Robotic microfluidic platform brings AI to lipid nanoparticle design
AI has designed candidate drugs for antibiotic-resistant infections and genetic diseases. But efforts to incorporate AI into the design of lipid nanoparticles (LNPs), the revolutionary delivery vehicles behind mRNA therapies ...
Phys.org / Nanosecond light-by-light switching achieved in liquid crystal droplet
Controlling light with light is a long-sought goal for computing and communication technologies. Achieving this capability would allow optical signals to be processed without converting them into electrical signals, potentially ...
Medical Xpress / Blood immune 'fingerprint' may help predict serious side effects of new Alzheimer's drug
A team of University of Kentucky researchers has uncovered a surprising clue in the battle against Alzheimer's disease that could help doctors predict, and ultimately prevent, a common side effect of the newest generation ...
Phys.org / Unlocking the hidden pocket on a billion‑dollar drug target
For years, a protein inside our cells has quietly powered billions of dollars' worth of cancer drugs. Now a team of researchers have discovered that this workhorse protein, called cereblon, in addition to its known functions, ...
Medical Xpress / Global physical activity remains low despite two decades of guideline updates
The prevalence of physical activity among the global population has remained low for the last two decades despite a majority of countries making notable progress in developing policies that include physical activity, UTHealth ...
Medical Xpress / New research brings hope for earlier detection of pre-eclampsia
Pre-eclampsia is a life-threatening pregnancy complication that can strike suddenly, endangering both mother and child. Despite affecting roughly one in twenty pregnancies worldwide, clinicians have long lacked a reliable ...
Medical Xpress / The tryptophan switch? Why exercise boosts your mood
One in five Canadians is living with mental health challenges such as anxiety and depression at any one time.
Phys.org / How farming perennial plants can help us in times of climate change, food insecurity and social division
Climate change is threatening modern life in ways we are still finding, from food security to the economy to everyday living. It has been labeled a "threat multiplier" for its potential to complicate geopolitical relationships. ...
Phys.org / Five-minute test spots PFAS down to parts-per-trillion
When Sandia scientists Ryan Davis and Nathan Bays set out to find a better way to absorb and degrade PFAS in water sources, they kept running into the same issue: Detecting the chemicals in samples took too long. So, they ...