Medical Xpress news
Medical Xpress / Combination treatment benefits patients with advanced breast cancer that has spread to the brain
Patients with leptomeningeal metastasis (LM) have historically had few treatment options. Now, researchers from The University of Texas MD Anderson Cancer Center have found a combination of targeted therapies, tucatinib and ...
Medical Xpress / Cellular stress signal found to drive immune exhaustion and weaken cancer therapy
Cancer-fighting T cells do not simply "run out of energy." They are molecularly reprogrammed. For years, mitochondrial dysfunction has been recognized as a hallmark of exhausted T cells in tumors. Yet how metabolic stress ...
Medical Xpress / Cholecystokinin, not insulin, may be key hormone in obesity-driven pancreatic cancer
Obesity increases the body's need for insulin, forcing cells in the pancreas known as beta cells to ramp up insulin production to maintain blood sugar levels. Scientists have thought that this excessive insulin secretion ...
Medical Xpress / The next leap for AI scribes provides eyes in the clinic
The introduction of vision-enabled artificial intelligence (AI) to medical scribes—the recording devices used by doctors to document meetings with patients in real-time—could increase the accuracy of patient notes and save ...
Medical Xpress / Premature menopause raises long-term heart risk by 40%, large study reveals
Women who enter natural menopause before age 40 face about a 40% higher lifetime risk of developing coronary heart disease than women who experience menopause later, according to a large Northwestern Medicine study that is ...
Medical Xpress / Gene mutation tied to schizophrenia slows brain's updating of beliefs
One of the symptoms of schizophrenia is difficulty incorporating new information about the world. This can lead patients to struggle with making decisions and, eventually, to lose touch with reality. MIT neuroscientists have ...
Medical Xpress / A neuron pair in fruit flies that makes life or death decisions
For the fruit fly, a sense of taste is critical to whether it thrives or dies. The little winged creature has taste organs in its mouthpiece as well as throughout its body, including its legs, abdomen and wing margins. When ...
Medical Xpress / GLP-1 medications used to treat diabetes and obesity may also help alleviate symptoms of anxiety and depression
GLP-1 medications used to treat diabetes and obesity were associated with a reduced need for hospital care and sickness absence due to psychiatric reasons, a new study shows. The large register-based study was carried out ...
Medical Xpress / Why some breast cancers spread faster: Jagged1 may trigger a tissue-stiffening feedback loop
A research group led by Professor Cecilia Sahlgren at Åbo Akademi University (Finland) and the InFLAMES Research Flagship has identified a new mechanism directing the adverse remodeling of tumor tissue during breast cancer ...
Medical Xpress / Cancer drug protein target may also help fight influenza
A protein already targeted by FDA-approved cancer drugs may also help the body fight influenza, according to new research from The Jackson Laboratory (JAX). Published in Cell Reports, the study found that Programmed Death-Ligand ...
Medical Xpress / Novel X-ray technique could transform tissue diagnosis
A new X-ray imaging technique could transform how hospitals analyze tissue samples, potentially speeding up diagnoses and improving outcomes for patients, shows a new study led by UCL researchers. The technology, developed ...
Medical Xpress / 'Leaky' brain barrier revealed as driver of chronic brain damage in retired combat and collision sports athletes
Research, led by teams at Trinity College Dublin and the FutureNeuro Research Ireland Center, has pinpointed the mechanism linking some sports injuries to poor brain health in retired athletes. The research, published in ...