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Phys.org / 'Atomic snapshots' of proofreading enzyme could lead to better COVID-19 drugs
The closest-ever detailed look at a key enzyme inside the virus that causes COVID-19 could lead to more effective treatment of the disease. Nucleotide analogs are a common type of antiviral medication that mimic the genetic ...
Medical Xpress / AI screening tool gives pathologists 'spatial super vision' to detect hidden cancer
QIMR Berghofer scientists have developed an AI screening tool that harnesses the power of cutting-edge spatial biology analysis to give pathologists "super vision" to detect hidden genetic markers of cancer in standard patient ...
Medical Xpress / Oral small-molecule GLP-1 drugs penetrate deep into the brain to suppress cravings
A study has found that an emerging class of GLP-1 weight-loss drugs suppresses eating for pleasure, or hedonic feeding, in mice by modulating a reward circuit deep within the brain. This newly charted pathway—separate from ...
Science X / Huge tsunami in popular area for Alaskan cruises provides lessons in steep, mountainous terrain
When part of a mountain in southeast Alaska slid into the ocean last summer, it triggered the second highest tsunami ever recorded. That tsunami ran 481 meters—one-and-a-half times the height of the Eiffel Tower—up the wall ...
Medical Xpress / How HIV hijacks a cellular 'gateway' to infect resting immune cells
Researchers from Queen Mary University of London have uncovered a previously unknown mechanism by which HIV-1 can infect resting immune cells. The discovery challenges a decades-old assumption in HIV biology, and opens new ...
Phys.org / Bacterial protein map could open new path against drug-resistant infections
La Trobe scientists have made a pivotal discovery in the fight against dangerous drug-resistant bacteria, as the University launches a major research initiative focused on new ways to target antimicrobial resistance (AMR). ...
Phys.org / 5th-century Belgian burial with 'scrap metal' may reveal missing link between Roman and Merovingian monetary systems
A study published in the journal Britannia analyzed coins and metal items found in an early 5th-century AD burial in Oudenburg, Belgium. The burial occurred around the same time that base metal coins ceased arriving in northwestern ...
Medical Xpress / Blood test reveals nine tumor cell 'neighborhoods' tied to immunotherapy outcomes
A simple blood test can reveal the geographic relationships among healthy cells surrounding a cancerous tumor, researchers at Stanford Medicine and the Mayo Clinic have found. The test is the first noninvasive way to study ...
Science X / Coffee doesn't just wake you up—a key biological pathway illuminates widespread health effects
For decades, research has linked coffee consumption to longer life and lower risk of chronic disease—but exactly how those benefits occur has remained unclear. Now, new research from the Texas A&M College of Veterinary Medicine ...
Tech Xplore / Stress-testing method for cloud computing algorithms helps avoid network failures
Researchers from MIT and elsewhere have developed a more user-friendly and efficient method to help networking engineers identify potential system failures before they cause major problems, like a cloud service outage that ...
Phys.org / Why isolated human groups speak more diverse languages even as genetic diversity shrinks
Languages and human DNA both capture aspects of human diversity. But how are they related? A new international study led by the University of Zurich finds a clear but counterintuitive pattern: regions with high genetic diversity ...
Medical Xpress / RNA blood markers may reveal illness trajectory and treatment success within days
Scientists are developing a test which could one day be used to predict how a patient's illness will progress, and even how well they will respond to treatment. The international team, led by researchers at Imperial College ...