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Phys.org / Fentanyl makeover: Core structural redesign could lead to safer pain medications
Fentanyl is one of the most effective drugs for managing severe pain, yet it carries substantial risks of addiction and respiratory depression, the dangerous and sometimes fatal slowed breathing. These safety concerns have ...
Phys.org / New perspectives on how physical instabilities drive embryonic development
Multicellularity is one of the most profound phenomena in biology, and relies on the ability of a single cell to reorganize itself into a complex organism. It underpins the diversity in the animal kingdom, from insects to ...
Phys.org / Ambitious climate action could save 1.32 million lives a year by 2040
Ambitious climate action to improve global air quality could save up to 1.32 million lives per year by 2040, according to a new study. The research, led by Cardiff University, shows how developing countries rely heavily on ...
Phys.org / mRNA fragments reveal a hidden process that protects cells from harmful mutations
Some genetic mutations that are expected to completely stop a gene from working surprisingly cause only mild or even no symptoms. Researchers in previous studies have discovered one reason why: cells can ramp up the activity ...
Medical Xpress / Gut microbes bolster immunity in HIV patients, research reveals
The circumstances surrounding a study on a deadly virus could hardly have been more dramatic. One of its first authors was forced to flee his homeland when it became a war zone. More than 2,000 kilometers away, the laboratory ...
Medical Xpress / Mapping the role of a master regulator in early brain development
New findings from Karolinska Institutet reveal how the gene HNRNPU coordinates several fundamental molecular processes during the earliest stages of human brain development. The study is published in Nucleic Acids Research ...
Medical Xpress / A kidney drug may help restore fertility in premature ovarian insufficiency
A common kidney medication could be the key to treating a type of infertility that affects up to 3% of women under 40, according to a study published in Science.
Phys.org / Exploring how the Gulf Stream affects the climate system and the carbon cycle
It is well documented that the Gulf Stream plays a pivotal role in the climate system through its transfer of heat, which ultimately supplies warmth to northern latitudes in the North Atlantic. What remains less well understood ...
Phys.org / How AI is distorting online research, from polls to public policy
Artificial intelligence is increasingly able to simulate human behavior and answer online surveys and political polls, putting the reliability of survey-based research at risk. Consequences can be serious, not only for science ...
Medical Xpress / How lung tumors use the brain to avoid immune attacks
University of Pennsylvania Perelman School of Medicine and Yale University School of Medicine, along with other collaborators, report that lung adenocarcinoma can engage nerve pathways that link the lung to the brainstem ...
Phys.org / When consent meets reality: How young men navigate intimacy
A new study suggests that young men overwhelmingly support affirmative sexual consent in principle—yet often find its verbal implementation difficult in practice. The research, led by scholars at Columbia University's Mailman ...
Phys.org / A DNA 'on-off' switch? Light and redox cues reversibly link strands for nanotech
DNA, the blueprint of life, is best known for its fundamental role as genetic material—storing and transmitting biological information through the precise sequence of its bases. For decades, this information-storage function ...
