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Medical Xpress / One molecule, two effects: A new drug concept to treat obesity and type 2 diabetes
A team led by metabolism researcher Prof Timo D. Müller at Helmholtz Munich has developed a new approach for treating obesity and type 2 diabetes: a hybrid molecule uses the well-known GLP-1/GIP signaling pathway as a "door ...
Medical Xpress / Rethinking mRNA vaccines: Liver targeting can suppress immunity, while muscle boosts it
A new study by researchers at the Icahn School of Medicine at Mount Sinai overturns a longstanding assumption about how mRNA vaccines generate immunity, revealing that certain non-immune cells help determine vaccine effectiveness.
Science X / A good yawn might do more than you think, say researchers
A simple yawn may feel like the most ordinary of human acts—a reflex triggered by tiredness, boredom, or seeing someone else's mouth stretch wide. But scientists still cannot say with certainty why we do it.
Phys.org / How hard-surface feeding unlocked a burst of reef fish evolution 50 million years ago
Why are there so many species of coral reef fish? According to a new study, it's because about 50 million years ago, some fish figured out how to bite food from hard surfaces.
Phys.org / Wreckage of a US Coast Guard ship lost during WWI has been found off the coast of England
The wreckage of a U.S. Coast Guard ship lost in a deadly attack more than a century ago, during World War I, was been discovered off the coast of England.
Phys.org / How cells decide when to react could shape future treatments for cancer and fibrosis
Scientists have discovered how cells decide when to respond to physical forces, potentially opening new avenues for tackling diseases such as cancer and fibrosis.
Phys.org / Low-cost method could standardize microplastic extraction from soils worldwide
A new "gold standard" for soil analysis and microplastic extraction has been developed at the University of New England (UNE), unlocking vital capabilities to safeguard agricultural soils and protect human health. Led by ...
Medical Xpress / A natural molecule boosts CAR-T therapy and turns cold tumors hot
CAR-T cell therapy works well in blood cancers, but many patients still become resistant. A key reason is the presence of CAR-T regulatory T cells (CAR-Tregs), which weaken immune responses. Therefore, selectively targeting ...
Phys.org / Light can now be shaped in empty space, and it could simplify sensing and boost data links
Scientists at the University of East Anglia have uncovered a hidden property of light that allows it to twist, spin and behave differently—without mirrors, materials or special lenses. In a breakthrough that could transform ...
Phys.org / Spintronics at BESSY II: Real-time analysis of magnetic bilayer systems
Spintronic devices enable data processing with significantly lower energy consumption. They are based on the interaction between ferromagnetic and antiferromagnetic layers. Now, a team from Freie Universität Berlin, HZB and ...
Phys.org / Antibodies need a strong core—not just grip—to fight SARS-CoV-2
An international research team has identified a previously overlooked factor that influences how antibodies neutralize SARS-CoV-2: their mechanical stability under force. Antibodies are key components of the immune system ...
Phys.org / Embryo epigenome follows universal physical rules, reshaping views of early cell fate
The development of an embryo is one of the most fundamental processes in biology. Early in this process, it is determined which cells will give rise to which tissues—controlled by epigenetic marks such as DNA methylation. ...