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Phys.org / Large-scale cell screening uncovers molecular glues that trigger protein degradation
Cells constantly monitor and recycle their proteins through a tightly regulated waste-disposal system. Proteins that are no longer needed are tagged and broken down by specialized cellular machinery. Recent advances in drug ...
Medical Xpress / Study finds tirzepatide cuts alcohol intake by more than half in rodents
For the first time, researchers show that tirzepatide—the active ingredient in the diabetes and weight-loss drug Mounjaro—reduces alcohol intake as well as relapse-like behaviors in rats and mice. The findings are considered ...
Medical Xpress / Why it's funnier when you're not allowed to laugh
I don't think I've ever laughed harder than during a church service, when something faintly ridiculous caught my eye. My friend saw it too, and once she started laughing, it became impossible to stop. Years later I've tried ...
Phys.org / Map suggests up to 30% of western bird hotspots face severe wildfire risk
Up to 30% of bird diversity hotspots, places where large numbers of different bird species occur, in the western United States face threats from high-severity wildfires in the future that could eliminate critical forest habitats, ...
Phys.org / Climbing behaviors of tree-dwelling mammals unlock insights on early primate evolution
Researchers have shed new light on the features that enable tree-dwelling mammals to move effectively through their environments, providing insights into the evolution of the distinct upright postures seen in primates. The ...
Phys.org / Why hikers need a backup for the maps on their phones
Four of five Norwegians use digital maps when they are in the outdoors. In just a few years, our mobile phones have gone from being a practical navigation aid to a virtual compass in your backpack. The more we rely on digital ...
Phys.org / Gotland hunter-gatherer graves hint at how Stone Age families organized
A woman was buried with two children, but they were not her own. In another grave, two children were placed. They were not siblings and were more distantly related, perhaps cousins. In a new study published in the Proceedings ...
Phys.org / Letting children play can support development
Preschool-age children are most engaged in pretend play 10–15 minutes after playing begins. In addition, girls exhibit higher organizational skills, according to a study conducted by researchers from SWPS University and ...
Medical Xpress / Q&A: How attending an HBCU can help reduce dementia risk
Attending a historically Black college or university (HBCU) can be linked to better cognitive performance decades later among Black adults, according to a study coauthored by Min Hee Kim, an assistant professor at Rutgers ...
Medical Xpress / Uneasy at the dentist? You're not alone
Settling into a cushy reclining chair and closing your eyes while soft music plays is appealing, except perhaps at the dentist's office. According to a recent report in the Journal of the American Dental Association, 72% ...
Phys.org / Trapping a single protein in a molecular cage: A new path to drug discovery for amyotrophic lateral sclerosis
Proteins often function in pairs or groups, concealing their internal connection points and making it difficult for scientists to study their individual units without altering their natural structure. In a study published ...
Phys.org / Simulations map how single-crystal battery materials could boost cycle life
The performance of rechargeable batteries is governed by processes deep within their components. A fundamental understanding of electrochemistry, structure–property–performance relationships and the effects of processing ...
