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Medical Xpress / Glucocorticoid injection shows little benefit for knee osteoarthritis, clinical trial finds
Researchers in China have found no statistically significant advantage for infrapatellar fat pad glucocorticoid injection over saline for 12-week knee pain change or effusion synovitis volume change in inflammatory knee osteoarthritis.
Phys.org / Tightening the focus of subcellular snapshots: Combined approach yields better cell slices for cryoET imaging
Taking images of tiny structures within cells is tricky business. One technique, cryogenic electron tomography (cryoET), shoots electrons through a frozen sample. The images formed by the electrons that emerge allow researchers ...
Phys.org / Complex life on planets orbiting the galaxy's most common stars may be unlikely
In a blow to anyone dreaming that complex life may exist elsewhere in the universe, a new study suggests we're unlikely to find it around many of the most common stars in the galaxy.
Phys.org / New temperature record challenges extreme high-latitude warmth paradigm
Reliable predictions of how the Earth's climate will respond as atmospheric carbon dioxide levels increase are based on climate models. These models, in turn, are based on data from past geological times in which the CO2 ...
Medical Xpress / 3D hybrid imaging system could address limitations of MRI, CT and ultrasound
In a proof-of-concept study, researchers from the Keck School of Medicine of USC and the California Institute of Technology (Caltech) have shown that an innovative, noninvasive technique can be used to quickly collect 3D ...
Phys.org / AI tools speed development of antibody probes to see activity inside living cells
Researchers at Colorado State University have determined how to use artificial intelligence to modify antibodies so they act as lightbulbs, enabling scientists to better see inside living cells to track errors in gene expression ...
Phys.org / Massive impact could be the cause of our lopsided moon
Our nearest neighbor, the moon, is still something of a mystery to us. For decades, scientists have wondered why it appears so lopsided, with dark volcanic plains on the near side (the side we see) and rugged, cratered mountains ...
Phys.org / How concrete jungles could be changing dandelion seed dispersal in Japan
Dandelions are incredible plants with a highly efficient seed-dispersal system, meaning even a gentle breeze can carry seeds and their parachutes great distances. But in several places in Aichi Prefecture, Japan, they have ...
Phys.org / British redcoat's lost memoir reveals harsh realities of life as a disabled veteran
Archival discoveries including a 19th-century autobiography transform our understanding of Shadrach Byfield, an English veteran of the War of 1812 who buried his own amputated arm and designed a custom prosthesis.
Phys.org / Decoded rules of microRNA strand selection reveal conserved, programmable features
MicroRNAs, whose discovery was recognized with the 2025 Nobel Prize in Physiology or Medicine, are central regulators of gene expression, yet a fundamental question has remained unanswered: how cells choose between the two ...
Phys.org / Indoor ozone reaction products can make blood thicker
Ozone that protects us from the sun's harmful UV rays, when in an indoor space, reacts with oils present on skin, wall paint, or even cooking oil to produce chemicals that negatively impact cardiovascular health.
Phys.org / A new 'crystalline sponge' for drug discovery: APF-80 illuminates materials design
Many natural compounds that act on the human body provide active ingredients for medicines or clues for developing them, and they play a crucial role in pharmaceutical research.
