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How does electrical stimulation modulate electrophysiological environment after SCI?

November 6th, 2013

An injury potential is the direct current potential difference between the site of spinal cord injury and the healthy nerves. Its initial amplitude is a significant indicator of the severity of spinal cord injury. This injury potential, as well as injury current, can be modulated by direct current field stimulation; however, the appropriate parameters of the electrical field are hard to define. Dr. Guanghao Zhang and colleagues from Institute of Electrical Engineering, Chinese Academy of Sciences, China found that electrical stimulation using a reversed electrical field polarity can effectively modulate the injury potential and benefits the spontaneous repair of the cell membrane in rats with spinal cord injury.

Taking the injury potential value as the parameter of the electrical stimulator, a method for de-fining the stimulation intensity is proposed, thus promoting the application of electrical stimulation in spinal cord injury. These results were published in the Neural Regeneration Research (Vol. 8, No. 27, 2013).

More information:
Zhang GH, Huo XL, Wang AH, Wu CZ, Zhang C, Bai JZ. Electrical stimulation modulates injury potentials in rats after spinal cord injury. Neural Regen Res. 2013;8(27):2531-2539.

Provided by Neural Regeneration Research

Citation: How does electrical stimulation modulate electrophysiological environment after SCI? (2013, November 6) retrieved 7 January 2026 from https://sciencex.com/wire-news/145194556/how-does-electrical-stimulation-modulate-electrophysiological-en.html

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