Creating a vaccine against canine gum disease

Gum disease, also known as gingivitis, is one of the most prevalent medical conditions in adult dogs. It is so common, most dogs will start to show signs of damage to their teeth and gums by three years of age. If this disorder is left untreated, it can lead to pain, gum damage and even tooth loss. This past month, the AKC Canine Health Foundation (CHF) awarded two research grants for the improvement of oral health in dogs. One of the research grants was awarded to Paola Massari, Ph.D, a Research Assistant Professor in the Section of Infectious Disease at Boston University School of Medicine (BUSM).

Currently treatment for dogs with gum disease is manual removal of plaque and tartar. This method does not provide a cure and only delays the disease progression. Massari's research focuses on prevention, stopping the disease before it has a chance to cause damage. She will be using the grant to develop a vaccine against the most common types of bacteria that lead to periodontal disease in dogs.

Massari received her PhD and post-doctoral training at the University of Naples "Federico II" and Chiron-Biocine in Siena, Italy. She is the author of numerous publications in the field of Infectious Diseases, with a special interest in understanding how interactions between bacteria and their hosts lead to the manifestation of disease. She chose to expand her research into companion animal health, in order to help fill the gap that currently exists in veterinary research.

Provided by Boston University Medical Center