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Some medications increase risk of blood vessel constriction in extremities

March 7th, 2016

A recent review of the medical literature has identified 12 classes of drugs and 4 main pathophysiological mechanisms that can cause a side effect whereby small arteries that supply blood to the skin constrict in response to cold, limiting blood supply.

The condition is called Raynaud's phenomenon.

"Beyond chemotherapies and beta-blockers, well known to induce Raynaud phenomenon, insights are currently emerging from a wide variety of drug classes through new pathophysiological pathways," said Dr. Charles Khouri, lead author of the British Journal of Clinical Pharmacology study.

More information:
Charles Khouri et al. Drug-induced Raynaud's phenomenon: beyond beta-blockers, British Journal of Clinical Pharmacology (2016). DOI: 10.1111/bcp.12912

Provided by Wiley

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