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Does vitamin D reduce likelihood of wheezing in preterm black infants?

May 22nd, 2018

Bottom Line: Black infants born preterm who received sustained vitamin D supplementation had a lower likelihood of recurrent wheezing by age 1.

Why The Research Is Interesting: Wheezing is a common complication of preterm birth and black infants have higher rates of prematurity-associated wheezing. This randomized clinical trial assessed two vitamin D supplementation strategies in preventing recurrent wheezing.

Who and When: 300 black infants born at 28 to 36 weeks between January 2013 and January 2016.

What (Study Interventions and Measures): 400 IU/day of vitamin D until 6 months of age adjusted for prematurity or a diet-limited approach (stopping supplementation once a baby was receiving at least 200 IU/day of vitamin D from formula or a fortifier added to human milk) (interventions); recurrent wheezing by age 1 (outcome).

How (Study Design): This was a randomized clinical trial (RCT). RCTs allow for the strongest inferences to be made about the true effect of an intervention. However, not all RCT results can be replicated in real-world settings because patient characteristics or other variables may differ from those studied in the RCT.

More information:
JAMA, doi:10.1001/jama.2018.5729

Provided by The JAMA Network Journals

Citation: Does vitamin D reduce likelihood of wheezing in preterm black infants? (2018, May 22) retrieved 22 September 2025 from https://sciencex.com/wire-news/288444519/does-vitamin-d-reduce-likelihood-of-wheezing-in-preterm-black-in.html

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