Five advances that could change heart health monitoring
February is American Heart Month, which puts a spotlight on cardiovascular health. According to the American Heart Association, heart disease is the leading cause of death for Americans, so it's important to know the status of your own heart health.
New methods for cardiac monitoring can be found in these five papers recently published in ACS journals.
- Future electrocardiography (better known as ECG or EKG) monitoring could be done with self-powered electrodes. A study in ACS Applied Nano Materials details how a flexible heart rhythm sensor generates power from a person's movements. Real-time heart rate and ECG signals were collected by flexible electrodes placed on a person's chest, fingertip and wrist and transmitted wirelessly.
- Proof-of-concept test strips could identify the severity of congestive heart failure in about 30 minutes. Reporting in ACS Sensors, researchers developed paper-based strips that measure blood serum for three known markers of heart failure. When combined with a smartphone-connected reader, the method accurately indicated the cardiac disease severity of 13 out of 14 people.
- A soft implant to assess post-surgery heart function could dissolve in the body and avoid a follow up surgery to remove it. The flexible, biocompatible device has components that sense changes in levels of lactic acid and volatile organic compounds, as well as pH and pressure. Demonstrations on a beating, 3D-printed silicone heart model and 3D-printed cardiac tissue patches showed the device's potential for cardiac monitoring, as published in ACS Sensors.
- Next-generation implantable "smart" stents could wirelessly monitor blood flow and blood pressure. Authors report in ACS Sensors that the technology, which opens previously obstructed arteries, self-reports an unprecedented level of information on arterial function. In a 3D-printed system mimicking the beating of a human heart, the stent relayed systolic and diastolic pressures and detected blockages occupying up to 50% of a blood vessel.
- Blood biomarkers could indicate brain inflammation and neuronal injury after cardiac arrest. Multiple circulating immune cells were identified as indicators from preclinical animal studies of cardiac arrest and resuscitation. Researchers say the biomarkers could be incorporated into blood tests to predict and improve neurological outcomes in cardiac arrest patients, as reported in ACS Chemical Neuroscience.
More information:
Junyao Wang et al, Graphene/Carbon Nanotube Conductive Ink-Based Biomimetic Structure for Self-Powered Flexible Medical Monitoring Devices, ACS Applied Nano Materials (2024). DOI: 10.1021/acsanm.3c05095
Xin Liu et al, Triple Cascade Quantum-Strip for Heart Failure Point-of-Care Testing, ACS Sensors (2024). DOI: 10.1021/acssensors.3c01217
Rawan Omar et al, Biodegradable, Biocompatible, and Implantable Multifunctional Sensing Platform for Cardiac Monitoring, ACS Sensors (2024). DOI: 10.1021/acssensors.3c01755
Nomin-Erdene Oyunbaatar et al, Implantable Self-Reporting Stents for Detecting In-Stent Restenosis and Cardiac Functional Dynamics, ACS Sensors (2023). DOI: 10.1021/acssensors.3c01313
Huanyu Dou et al, Fingerprint of Circulating Immunocytes as Biomarkers for the Prognosis of Brain Inflammation and Neuronal Injury after Cardiac Arrest, ACS Chemical Neuroscience (2023). DOI: 10.1021/acschemneuro.3c00397
Provided by American Chemical Society