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Medical Xpress / Micropores enhance organ-on-chip models for studying hidden infections
A new study provides a powerful way to study infections in environments that closely mimic human organs. The strategy, tested in a bone-marrow-on-chip model, was developed by researchers from the Barcelona Institute for Global ...
Medical Xpress / Bone marrow model built entirely from human cells can reduce animal testing
Our body's "blood factory" consists of specialized tissue made up of bone cells, blood vessels, nerves and other cell types. Now, researchers have succeeded for the first time in recreating this cellular complexity in the ...
Phys.org / Nanoparticle–stem cell hybrids open a new horizon in bone regeneration
A research team in South Korea has successfully developed a novel technology that combines nanoparticles with stem cells to significantly improve 3D bone tissue regeneration. This advancement marks a step forward in the treatment ...
Phys.org / Tissue 'tipping points': How cells collectively switch from healthy to disease states
Cells convert mechanical forces into signals that influence physiological processes, such as exercise strengthening bones. A research team at Washington University in St. Louis and Tsinghua University in Beijing have discovered ...
Medical Xpress / How new advances in 3D bioprinting, organoids and organs on-a-chip aid in the fight against cancer
Scientists are exploring leading-edge technologies that could transform how cancer is studied, detected and treated by catching it earlier, when it's more treatable and survival rates are highest.
Medical Xpress / Stem cells sound magical, but they're not all created equal—here's what you need to know
Most people have heard of stem cells. They are often described as "miracle" cells –ones that can grow into any other type of cell in our bodies, promising revolutionary medical treatments.
Medical Xpress / Scientists find cells that know when, where and how to grow teeth
Tooth development is a dynamic process that involves the stages of the bud, the cap, and the bell, followed by root development and subsequent tooth formation. Processes such as the bud-to-cap transition are mediated by epithelial-mesenchymal ...
Tech Xplore / Harnessing disorder: Metamaterials researchers achieve static mechanical cloaking and camouflage
A new collaborative study between IMDEA Materials Institute, China's Northwestern Polytechnical University, the Chinese Academy of Sciences, Peking University, and the Southern University of Science and Technology, has achieved ...
Medical Xpress / Rethinking how bone marrow works with a unified framework
One huge reason why the world of medicine hasn't yet found "the cure" for hard-to-treat malignancies like acute myeloid leukemia (AML) and many other forms of cancer is that the world of science is still striving to fully ...
Medical Xpress / Hip or shoulder? Location matters for bone marrow used in joint repair
Bone marrow aspirate concentrate (BMAC) is a common treatment for joint injuries. The invasive therapy involves extracting bone marrow—often from the hip—and concentrating it to preserve stem cells and growth factors, ...
Phys.org / How protein coatings influence nanoparticles' ability to avoid immune clearance and reach their destinations
Nanomedicine uses ultra-small particles to deliver drugs directly to the tissues and cells that need them, improving treatment effectiveness while reducing side effects. This approach underpins some clinically approved RNA-based ...
Phys.org / Getting the dose right in reprogramming cells
EPFL researchers have uncovered how transcription factor dosage reshapes cell identity, showing that even small differences in dose can steer cells toward completely different fates. Their findings reveal a new layer of control ...
