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By turning a patient's own immune cells into stronger cancer-fighting cells, CAR T-cell therapy has transformed how some blood cancers are treated. But it's been harder to extend this approach to solid tumors, including cancer ...

In a new Nature Physics study, researchers found that fin regrowth in zebrafish is driven by a brief burst of growth signal at the fin tip, sized to the amount lost, which sets up gradients of Erk activity that guide the ...

If you've ever created a snowflake by folding, cutting and unfolding a piece of paper, you've practiced the art of kirigami. Like origami, kirigami has inspired innovations far beyond the elementary school classroom, with ...

A research team from the Faculty of Dentistry at The University of Hong Kong (HKU), working in collaboration with Su Ryon Shin's group at Brigham and Women's Hospital, Harvard Medical School, has advanced and preclinically ...

Opioid painkillers are some of the strongest analgesic medicines, but they are also the riskiest owing to a range of side effects, including addiction. An experimental opioid painkiller designed to be reversibly switched ...

The liver is organized into distinct zones in which liver cells perform different functions. The blood vessels of the liver play an important role in this spatial organization: the endothelial cells lining the vessels provide ...

Nature has spent millions of years optimizing the connection between bone and tendon. Over a very short distance, the body transitions from stiff bone to flexible tendon while maintaining strength and durability. Reproducing ...

The spread of cancer from a primary tumor to another place in the body, called metastasis, remains one of the greatest challenges in cancer treatment and is responsible for most cancer-related deaths.

Collagen is the most abundant protein in the human body, making up about 30% of total protein and providing structure, strength and elasticity to skin, bones and soft tissues.

One of the main reasons ovarian cancer is among the deadliest forms of cancer is timing: When doctors catch it early, the five-year survival rate can be more than 90%. But when doctors catch it late, in stages 3 or 4, five-year ...

Gevick Safarians remembers the conversations. Patients dealing with cancer and other diseases with very poor prognoses, hoping not for years but for months—a little more time to settle their affairs, to figure out who would ...

Researchers have engineered a drug treatment that shows rapid effectiveness against endometriosis in early testing, laying the foundation for a potential therapy for an incurable, chronic disease that affects 1 in 10 women. ...