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Medical Xpress / Update shows sustained overall survival benefit with adjuvant osimertinib in resected EGFR-mutated lung cancer
An exploratory 8-year landmark update from the Phase III ADAURA trial showed that adjuvant osimertinib continued to provide a long-term overall survival benefit for patients with completely resected, EGFR-mutated stage IB–IIIA ...
Phys.org / Researchers pinpoint key early-universe measurement with record precision
An international team, including researchers from the University of Minnesota Twin Cities, has reached a major milestone in "precision cosmology" by measuring the amount of helium created in the universe's first five minutes ...
Phys.org / A 1,000-fold longer charge lifetime helps organic catalyst produce solar hydrogen faster
Researchers from the Ningbo Institute of Materials Technology and Engineering (NIMTE) of the Chinese Academy of Sciences (CAS), in collaboration with researchers from the Technical Institute of Physics and Chemistry of CAS, ...
Medical Xpress / New US Medicare pricing policies could reshape global pharmaceutical markets
A new modeling study published in The Lancet suggests that U.S. Medicare's new "Most-Favored-Nation" pricing policy, which ties what Medicare pays for medicines to prices charged in other high-income countries, could push ...
Medical Xpress / Early blood protein clues could identify children at risk of cardiometabolic disease
Researchers at Vanderbilt Health, UTHealth Houston and the University of North Carolina at Chapel Hill have identified early signs of cardiovascular-kidney-metabolic disease (CKMD) in children as young as 8 years old that ...
Phys.org / Ancient armored fish evolved two distinct ways to crush prey 385 million years ago
Long before dinosaurs appeared on Earth, fierce predatory fish developed crushing jaws and sharp teeth to survive and diversify in ancient oceans.
Phys.org / Masked tectonic structures suggest Mercury contracted 40% more than its visible scars alone indicate
The surface of Mercury is filled with craters, ridges and steep cliffs. Over billions of years, as the planet's interior cooled, the planet also shrank. Just as the skin of a drying fruit wrinkles when what is inside it shrinks, ...
Medical Xpress / Rare cortical neurons can synchronize brain activity and promote sleep in mice
What makes the brain fall asleep? For nearly a century, scientists have looked to structures deep within the brain for the answer. In the traditional view, these regions control when we sleep and wake, while the cerebral ...
Phys.org / Consumers demand transparency, but is it rewarded?
Transparent supply chains boost consumer trust—if the results are positive. But what if they aren't? A new paper by Kühne Logistics University (KLU), in collaboration with the University of Tennessee and Tilburg University, ...
Medical Xpress / Aging oxidation drives brain proteins into harmful condensates, study finds
An international research team that included Martín Hugo, a Serra Húnter lecturer in the Department of Biochemistry and Molecular Biology at the UAB, has described how two opposing chemical modifications of proteins, sulfenylation ...
Phys.org / Astronomers unmask a supernova impostor
A distant star has captured astronomers' attention over the past decade, teasing them with indications that it will soon explode as a supernova. But new research shows that something else entirely is behind the star's outbursts. ...
Phys.org / Saltwater flooding could radically change which crops are worth growing
Saltwater isn't something most people associate with English farmland. But in parts of eastern England, it's becoming a growing problem, not just for crops but for farm incomes too.