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Medical Xpress / Subcutaneous tarlatamab shows favorable safety profile and antitumor activity in extensive-stage small cell lung cancer
Subcutaneous administration of tarlatamab was well tolerated and demonstrated preliminary antitumor activity in patients with previously treated extensive-stage small cell lung cancer (ES-SCLC), according to findings from ...
Phys.org / Nepal flood disaster exposes cascading threats in Himalayas
A catastrophic flood in Nepal that left thousands missing began with a collapse of ice and rock high in the mountains—a warning that disaster planning must prepare for chains of hazards, not isolated events, experts say.
Medical Xpress / Extended-interval tarlatamab dosing shows consistent activity and safety in previously treated small cell lung cancer
Extended-interval dosing regimens of tarlatamab demonstrated efficacy, safety and pharmacokinetic profiles generally consistent with the established every-two-week regimen in patients with previously treated small cell lung ...
Medical Xpress / PET/MRI improves presurgical lesion detection in pediatric epilepsy
In children with difficult-to-diagnose epilepsy, PET/MRI can pinpoint areas of the brain responsible for seizures, even when MRI scans are negative or inconclusive. A new study of a large pediatric cohort, including children ...
Medical Xpress / Rheumatoid arthritis: Timely diagnosis and early treatment initiation are key determinants of prognosis
Early, consistently managed treatment can have a decisive impact on the course of rheumatoid arthritis and prevent permanent joint damage. An international review led by Josef S. Smolen of the Medical University of Vienna ...
Medical Xpress / Pumitamig plus elfetabart drozuntecan shows encouraging early activity in small cell lung cancer
The investigational combination of pumitamig and elfetabart drozuntecan (elfe-D) demonstrated a manageable safety profile and encouraging early antitumor activity in patients with small cell lung cancer (SCLC), according ...
Medical Xpress / Investigational EGFR x HER3 therapy supports Phase III dose after lung cancer trial
An investigational EGFR x HER3 antibody-drug conjugate demonstrated promising efficacy with a tolerable safety profile in patients with previously treated EGFR-mutated non-small cell lung cancer (NSCLC), supporting selection ...
Medical Xpress / Perioperative atezolizumab + chemotherapy more than doubles event-free survival in resectable stage II–IIIB NSCLC
Patients with resectable stage II–IIIB non-small cell lung cancer (NSCLC) treated with perioperative atezolizumab plus platinum-based chemotherapy experienced a median event-free survival of 62.8 months compared with 34.9 ...
Medical Xpress / Local consolidative therapy does not improve survival after dual immunotherapy in metastatic NSCLC
Adding local consolidative therapy (LCT) after induction treatment with nivolumab plus ipilimumab did not improve overall survival or progression-free survival in patients with metastatic non-small cell lung cancer (NSCLC), ...
Phys.org / Scientists discover a strange new form of ice that could help explain the interiors of Neptune and Uranus
Scientists have discovered that there is ice deep inside planets like Neptune and Uranus and want to find out what form it takes and how it behaves. They cannot dig for it and transport it all the way back to Earth, so they ...
Phys.org / A photon that challenges Einstein: According to current physics, it should never have reached Earth
How did a photon survive a journey of more than 2 billion light-years when, according to known physics, it should have been absorbed long before reaching Earth? This is the question at the heart of a new study by Giorgio ...
Phys.org / 1,000 times faster operations bring reliable quantum computing a step closer
So far, quantum computers have been held back by their extreme sensitivity to errors and external disturbances. The longer a quantum operation takes, the greater the risk of computational errors.
