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Phys.org / Robotic microfluidic platform brings AI to lipid nanoparticle design
AI has designed candidate drugs for antibiotic-resistant infections and genetic diseases. But efforts to incorporate AI into the design of lipid nanoparticles (LNPs), the revolutionary delivery vehicles behind mRNA therapies ...
Medical Xpress / Long-read genome sequencing uncovers new autism gene variants
Researchers at the University of California San Diego have identified new genetic variants associated with autism spectrum disorder (ASD) by using long-read whole genome sequencing (LR-WGS), an emerging approach that reads ...
Medical Xpress / Mouse brain study reveals why blockbuster weight-loss drugs may work differently in females and males
The drugs have names that sound like small planets: semaglutide, liraglutide, lixisenatide. Collectively, they belong to a class of glucagon-like peptide 1 (GLP-1) analogs that has reshaped the treatment of obesity and diabetes ...
Phys.org / Lost page of the Archimedes Palimpsest identified in Blois, central France
A page long believed to have been lost from the Archimedes Palimpsest, one of the most important surviving manuscripts of antiquity, has been identified at the Musée des Beaux-Arts in Blois, central France, by a CNRS researcher. ...
Phys.org / Unlocking the hidden pocket on a billion‑dollar drug target
For years, a protein inside our cells has quietly powered billions of dollars' worth of cancer drugs. Now a team of researchers have discovered that this workhorse protein, called cereblon, in addition to its known functions, ...
Phys.org / A brighter future may not suit everyone: Polar cod face difficulties due to warming
Under the Arctic sea ice, fish and plankton live in complete darkness, even in midsummer. Ice floes stop the sun's rays, especially if they are covered by snow. As the ocean heats up, the sea ice thaws, and new regions are ...
Medical Xpress / Deep-frozen brain region restarts electrical activity after thawing
Researchers at Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) and Uniklinikum Erlangen have succeeded in preserving brain tissue through extreme deep freezing. After thawing, the neurons begin exchanging electrical ...
Phys.org / Five-minute test spots PFAS down to parts-per-trillion
When Sandia scientists Ryan Davis and Nathan Bays set out to find a better way to absorb and degrade PFAS in water sources, they kept running into the same issue: Detecting the chemicals in samples took too long. So, they ...
Phys.org / Scientists trace crop viruses back to the last Ice Age
Long before humans cultivated crops or sailed between continents, a group of plant viruses was already evolving among wild plants in Eurasia. According to a new international study published in Plant Disease, the ancestors ...
Phys.org / How changes on the Y chromosome may make species reproductively incompatible
When closely related species mate, their offspring sometimes survive but cannot reproduce. This pattern often affects males first, with hybrid males frequently failing to produce functional sperm even when hybrid females ...
Phys.org / Record-energy neutrino may have begun its journey in blazars
Three years ago, in the waters of the Mediterranean Sea, the passage of an "ultra-energetic" cosmic neutrino was observed—the most energetic ever detected. The event drew international attention from the scientific community ...
Tech Xplore / Can tomorrow's grid handle extremes? New simulations test renewables far faster
As power grids add more renewable energy and large-scale battery storage, utilities face a growing challenge: how to stress-test tomorrow's electricity systems before investing billions to build them. Wind, solar and battery-backed ...
