Medical Xpress news
Medical Xpress / Advanced MRI data set maps adolescent brain development
Researchers have created a large, openly available neuroimaging resource from more than 24,000 MRI scans of over 10,000 adolescents, providing a view of how the brain's wiring develops during adolescence. Using advanced, ...
Medical Xpress / Common deworming drug helps restore lung cancer's sensitivity to targeted therapy in mice
A form of lung cancer, which is found in about 10%–15% of Western patients and 40%–50% of Asian patients, is driven by a mutation in the epidermal growth factor receptor (EGFR) gene. Gefitinib is a go-to drug that shuts down ...
Medical Xpress / A gut microbe makes a fatty acid that cuts artery plaque in half in mice
A common gut bacterium produces a molecule that slows cholesterol production in the liver. When researchers gave the molecule to mice prone to artery disease, the animals developed roughly half as much fatty plaque as untreated ...
Medical Xpress / AI misuse and nuclear famine could threaten humanity's survival before 2100
The fate of global health does not rest on any single disease. True preparedness means pairing the fight against illness with strength in finance, climate, defense and security. The COVID-19 pandemic, which brought the world ...
Medical Xpress / Reversing age by reprogramming gene expression networks
Every organ and tissue progressively loses function and integrity as it ages. In fact, researchers have identified "hallmarks of aging" that not only present specific processes impacted by age, but are also thought of as ...
Medical Xpress / Reversible genetic switches could give cancer immunotherapy more precise control
A genetic switch that activates immune cells as they fight tumors: this is the new strategy developed by an international research team coordinated by Velia Siciliano at the Istituto Italiano di Tecnologia (IIT—Italian Institute ...
Medical Xpress / Maternal vaccination helps protect newborns from deadly bacterial bloodstream infections, mouse study suggests
Researchers at Washington University School of Medicine in St. Louis found that a vaccine given to pregnant mice protected their newborn pups from a severe bloodstream infection caused by Klebsiella pneumoniae, a dangerous ...
Medical Xpress / Commonly prescribed blood-pressure drug may stimulate 'healthy' brown fat
Scientists have discovered that the drug losartan, commonly prescribed for high blood pressure, boosts brown adipose tissue activity in mice, enhancing their metabolism. This indicates that repurposing losartan—an angiotensin ...
Medical Xpress / Skin measurements show link between insomnia and disrupted fear responses
A new computational model using skin conductance measurements to estimate stress-related emotional arousal found a significant difference in learned fear and safety responses over time between adults with and without insomnia.
Medical Xpress / What if mosquito saliva holds the key to better fighting Zika, dengue and West Nile viruses?
Mosquitoes do more than simply transmit the viruses they carry: Their saliva may actively help these viruses establish infection in the body from the very moment of the bite. This is the finding of a study conducted by a ...
Medical Xpress / Trapping cancer-driving DNA rings outside cell nucleus silences their genes, researchers find
Cells from rapidly growing, highly metastatic tumors often contain numerous rings of extrachromosomal DNA (ecDNA). This circular DNA frequently carries oncogenes—genes that promote cancer. Researchers have long sought vulnerabilities ...
Medical Xpress / Deep brain stimulation study links multiple pathways to sustained improvement in treatment-resistant depression
Stimulation of specific brain connections was associated with sustained improvement in people receiving deep brain stimulation (DBS) for treatment-resistant depression, Mount Sinai researchers reported. The findings could ...