Medical Xpress news
Medical Xpress / BRCA's cancer map just grew: Gene mutations now implicated in thyroid, bladder, skin and head-neck cancers
An international group led by researchers from the RIKEN Center for Integrative Medical Sciences (IMS) in Japan has discovered associations between pathogenic variants of the BRCA 1 and 2 genes and four types of cancer. Published ...
Medical Xpress / Off-label cancer drugs deliver durable benefit for some patients in large trial
The largest published prospective evaluation of off-label targeted cancer therapies has shown that more patients could benefit from existing drugs. After including over 1,600 patients in the Dutch multicenter DRUP trial, ...
Medical Xpress / Genome-wide analysis reveals host–virus genetic interactions in cancer risk
A study from Columbia University Mailman School of Public Health reports a major advance in understanding how interactions between human and viral genomes shape disease risk. The research found that variations in the Epstein–Barr ...
Medical Xpress / Immune system uses a conveyor belt-like process to edit defective antibodies, new research finds
The immune system's B cells create antibodies that can mount a response against just about anything—either destroying a pathogen or instructing the rest of the immune system to go after the offender. But what happens when ...
Medical Xpress / Mitochondria keep key immune cells battle-ready by sustaining electron flow, study reveals
Researchers at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) show that active mitochondria maintain dendritic cells, the immune system's sentinels, in a "ready-to-respond" state, linking cellular ...
Medical Xpress / A powerful new cancer map tracks hundreds of mutations to one escape route and exposes a drug target
Diseases like cancer or neurodegeneration are known to arise from genetic misfires. But treating such complex conditions hasn't been simply a matter of identifying the malfunctioning genes involved. With hundreds of genetic ...
Medical Xpress / Australian bee glue delivers a scar-fighting compound that shuts down raised scars before they take hold
A natural compound made by Australian bees to seal their hives may help stop scarring in human skin after surgery, injury and burns, according to University of the Sunshine Coast researchers. The scientists say the laboratory ...
Medical Xpress / Jury ruling sharpens questions over when heavy social media use becomes addiction
On March 25, a California trial awarded $6 million to a plaintiff who argued that the addictive qualities of social media had caused her harm. Google and Meta, which were the companies that were found liable, disagree with ...
Medical Xpress / 'MitoCatch' delivers healthy mitochondria to diseased cells
Scientists led by Botond Roska at the Institute of Molecular and Clinical Ophthalmology Basel (IOB) have developed MitoCatch, a system that enables targeted delivery of healthy mitochondria to specific cell types affected ...
Medical Xpress / Blood-based DNA signals may help track osteosarcoma in children
Detecting whether osteosarcoma, a rare but aggressive bone cancer that most often affects children and adolescents, has returned or spread remains a major challenge for patients and doctors. Blood-based biomarkers, which ...
Medical Xpress / A molecular movie captures cancer's great escape from targeted therapy
Cancer drugs are designed to shut tumors down. But sometimes, in the very act of attacking a tumor, treatment can also help a small fraction of cancer cells become harder to kill. A new study from researchers at the Institute ...
Medical Xpress / Blood test predicts kidney failure risk to Black Americans years before onset
A new blood test can identify which individuals of African ancestry carrying high-risk APOL1 gene variants are most likely to develop kidney failure, years before clinical disease becomes apparent. Findings on the new test, ...
