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Phys.org / From inhibition to destruction: Kinase drugs found to trigger protein degradation
Protein kinases are the molecular switches of the cell. They control growth, division, communication, and survival by attaching phosphate groups to other proteins. When these switches are stuck in the "on" position, they ...
Medical Xpress / How antibody therapy clears Alzheimer's plaques: Key immune mechanism identified
Lecanemab, sold under the name Leqembi, is a monoclonal antibody therapy for Alzheimer's disease that clears toxic amyloid plaques and delays cognitive decline. Researchers from VIB and KU Leuven have now demonstrated the ...
Phys.org / Polar ice melt offers unexpected solution to a global climate disaster
The Atlantic Meridional Overturning Circulation (AMOC), a system of Atlantic Ocean currents that redistributes heat and nutrients between the tropics and the North Atlantic, is one of the planet's tipping points. That means ...
Phys.org / Earthquakes shake up Yellowstone's subterranean ecosystems
Up to 30% of life, by weight, is underground. Seismic activity may renew the energy supply for subterranean ecosystems. Published in PNAS Nexus, Eric Boyd and colleagues chronicled the ecological changes in subsurface microbial ...
Phys.org / Island-wide field surveys illuminate land-sea connections in Mo'orea
A massive, multi-year scientific expedition led by researchers from the University of California, Santa Barbara and collaborating institutions, including the University of Hawai'i (UH) at Mānoa, determined that land use ...
Phys.org / The ingenuity of white oval squid camouflage brought to light
White oval squid (Sepioteuthis lessoniana sp. 2), known locally as shiro-ika, are medium-sized squids naturally distributed in the Indian and western Pacific oceans, flittering in and out of a wide range of different habitats—from ...
Phys.org / Quantum photonic chip integrates light-emitting molecules with single-mode waveguides
Photonic quantum processors, devices that can process information leveraging quantum mechanical effects and particles of light (photons), have shown promise for numerous applications, ranging from computations and communications ...
Medical Xpress / Alternative sweetener sorbitol linked to liver disease
Sweeteners such as aspartame, found in Equal packets, sucralose (Splenda), or sugar alcohols are often seen as healthier alternatives to food with refined sugar (glucose). But that assumption is being challenged with new ...
Phys.org / New deep-learning tool can tell if salmon is wild or farmed
A paper published in Biology Methods and Protocols, finds that it is now possible to distinguish wild from farmed salmon using deep learning, potentially greatly improving strategies for environmental protection. The paper ...
Phys.org / North and Baltic seas show widespread contamination by MRI contrasting agents
A comprehensive study by the CritMET research group, led by Prof. Michael Bau, a geochemist at Constructor University in Bremen, provides evidence of widespread contamination of the North Sea and the Baltic Sea with MRI contrast ...
Phys.org / Higher resolution climate models show 41% increase in daily extreme land precipitation by 2100
Despite continuous efforts to evaluate and predict changes in Earth's climate, most models still struggle to accurately simulate extreme precipitation events. Models like the Coupled Model Intercomparison Project Phases 5 ...
Phys.org / Second exoplanet discovered in the TOI-1422 system
European astronomers report the discovery of a second alien world in the TOI-1422 planetary system located some 500 light years away. The newfound exoplanet, which received designation TOI-1422 c, is nearly three times larger ...