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Medical Xpress / Targeting cell division protein CDK2 could boost immunotherapy response across a wide range of cancers
New research from Dana-Farber Cancer Institute scientists suggests that cyclin-dependent kinase 2 (CDK2) inhibitors, which are currently being tested as treatments that slow the growth of a narrow range of cancers, could ...
Phys.org / Salt may have helped turn Earth into a frozen world 700 million years ago
Earth may have been pushed deeper into a global deep freeze by something surprisingly ordinary: salt. Around 700 million years ago, Earth entered periods of extreme glaciation known as Snowball Earth, when ice is thought ...
Medical Xpress / Aging blocks the retina's ability to regrow lost neurons, a first-of-its-kind study finds
A new study from the laboratory of Levi Todd, Ph.D., at Upstate Medical University has found that aging significantly limits the ability of support cells in the retina, called glia, to be reprogrammed into new neurons, a ...
Medical Xpress / CRISPR gene-editing therapy safely and continuously lowers cholesterol and triglycerides, first-in-human trial shows
A Cleveland Clinic first-in-human clinical trial has shown that a one-time infusion of a gene-editing therapy using CRISPR-Cas9 was effective and safe in reducing LDL ("bad") cholesterol and triglycerides in people with medication-resistant ...
Phys.org / A new type of LED light could bring significant efficiency gains
Researchers at Lund University have developed a new type of light-emitting diode based on thin, branched nanowires that could offer significantly higher efficiency and lower production costs than current technology. By controlling ...
Medical Xpress / Low-dose THC keeps breast cancer cells in tumor models from reverting to an aggressive state
Recent discoveries have revealed that breast cancer cells are more flexible than previously thought. Some can change from a differentiated state, when a mature cell has taken on a specific function, back to a more stem-like ...
Tech Xplore / Brain activity patterns could help sharpen LLM deductive reasoning
Large language models (LLMs), the artificial intelligence systems underpinning the functioning of ChatGPT, Gemini and other similar conversational agents, are now widely used worldwide. In addition to processing, interpreting ...
Phys.org / More than 120 molecular species found in giant cloud near Milky Way's center
Astronomers have discovered a second interstellar cloud near the center of the Milky Way that is extraordinarily rich in complex molecules, including several molecules associated with prebiotic chemistry. The newly studied ...
Phys.org / Away from grand temples, a recycled Bronze Age burial mound became the focus of a Roman religious complex
The Romans were master engineers, building sprawling road networks, towering aqueducts and arenas across their empire. They were also good at recycling. New research has revealed that they turned the remains of a 4,000-year-old ...
Medical Xpress / Energy-hungry tissues expand cleanup crews to clear worn-out mitochondria
The body's heart muscle (for pumping blood), skeletal muscle (for movement and posture) and brown fat (for heat production) each require a lot of energy and make a lot of waste. That waste needs to be managed.
Medical Xpress / Immediate coronary angiography fails to boost survival after cardiac arrest, trial finds
Immediate coronary angiography did not improve 30-day survival compared with a deferred strategy in patients without ST-segment elevation on an ECG after out-of-hospital cardiac arrest. These were the main findings of the ...
Tech Xplore / Long AI conversations reveal misinformation vulnerabilities across seven leading chatbots
The results are in: Which AI model is the most fallible? Persuadable? Correctible? University of Arizona researchers assessed seven different generative AI large language models, or LLMs, for these three qualities during ...
