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Medical Xpress / Scientists uncover key driver of treatment-resistant cancer: Genome-scrambling enzyme points to new treatments

University of California San Diego researchers have discovered the enzyme responsible for chromothripsis, a process in which a single chromosome is shattered into pieces and rearranged in a scrambled order, allowing cancer ...

Dec 11, 2025 in Oncology & Cancer
Phys.org / Hidden fuel for ocean microbes: Urea emerges as key energy source for marine ammonia oxidizers

Ammonia-oxidizing archaea (AOA) are some of the most abundant microorganisms in the ocean and play a key role in nitrogen cycling. Yet, despite their ubiquity, scientists have long puzzled over how these microbes can flourish ...

Dec 11, 2025 in Earth
Phys.org / Scientists teach helices to switch shapes

Researchers at the University of Jyväskylä have discovered a simple way to program synthetic molecules so they can form specific spiral-like structures by embedding instructions directly into their sequence. This breakthrough ...

Dec 11, 2025 in Biology
Medical Xpress / Missing myelin in key brain cells erases first wave of sensory signals

Our nerve cells are surrounded by a protective layer (myelin). This protective layer allows signals to pass between cells incredibly quickly. But what happens when this layer goes missing from cells that transfer signals ...

Dec 11, 2025 in Neuroscience
Medical Xpress / Blocking collagen signaling boosts drug delivery in pancreatic cancer

Pancreatic cancer is one of the deadliest malignancies, with survival rates remaining dismally low despite major advances in oncology. One of the key reasons lies in the disease's unique fibrotic microenvironment—a dense, ...

Dec 11, 2025 in Medical research
Phys.org / Wintertime spike in oceanic iron levels detected near Hawaii

Around the world, phytoplankton in the upper ocean help to cycle key nutrients and regulate Earth's climate by absorbing carbon dioxide. These photosynthesizing organisms rely on dissolved iron as an essential micronutrient, ...

Dec 11, 2025 in Earth
Phys.org / Adult female bark spiders produce superior and tougher silk than males do

Dragline silk or major ampullate (MA) silk, the part of a spider's web that forms the main frame and spokes, is one of the toughest materials known to science. That is, it can absorb massive amounts of energy from a sudden ...

Dec 9, 2025 in Biology
Medical Xpress / Antibody formulation could enable simple injections instead of lengthy hospital infusions

Antibody treatments for cancer and other diseases are typically delivered intravenously, because of the large volumes that are needed per dose. This means the patient has to go to a hospital for every treatment, where they ...

Dec 11, 2025 in Immunology
Medical Xpress / Study uncovers beneficial relationship between gardening and osteoarthritis

Gardening/yardwork is one of the few forms of leisure physical activity that people tend to do more as they age. Osteoarthritis is the most common form of arthritis and a major cause of disability that also tends to occur ...

Dec 12, 2025 in Arthritis & Rheumatism
Medical Xpress / How the cerebellum builds its connections with the rest of the brain during early development

For the first time, a team of researchers at the Institute for Neurosciences (IN), a joint center of the Spanish National Research Council (CSIC) and Miguel Hernández University of Elche (UMH), has reconstructed how the ...

Dec 11, 2025 in Neuroscience
Phys.org / Researchers map Africa's snaring crisis, calling for sustainable solutions

The thunder of a rifle echoes across the Savannah. Antelope scatter as birds of all feathers take to the air. A dull thud signals that the marksman's shot was true. The horn from the felled rhino will command more money on ...

Dec 12, 2025 in Biology
Medical Xpress / Tricking tumors into marking themselves for destruction with focused ultrasound

USC biomedical engineers have found a way to make a solid tumor paint a target on its own back in order to train the body's immune system to find and destroy it.

Dec 11, 2025 in Oncology & Cancer