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Medical Xpress / Mutant GFAP disrupts mitochondrial fission in astrocytes, offering insight into Alexander disease

Some brain disorders are straightforward, such as the direct frontal lobe assault of a concussion or traumatic brain injury. Others, like Alexander disease, are akin to guerrilla warfare. Patients suffering from this genetic ...

21 hours ago in Genetics
Medical Xpress / Unexpected pathway for IgA antibody production may help improve vaccines

Scientists led by Stephanie Eisenbarth, MD, Ph.D., the Roy and Elaine Patterson Professor of Medicine and director of the Center for Human Immunobiology, have discovered how critical IgA antibodies are produced through unexpected ...

22 hours ago in Immunology
Medical Xpress / Landscape of KRAS mutations and targeted therapies in colorectal cancer mapped in new study

A team of researchers from the Germans Trias i Pujol Research Institute (IGTP) and Institut Català d'Oncologia (ICO) has studied alterations in the KRAS gene in colorectal cancer by combining genomic analyses with a systematic ...

22 hours ago in Oncology & Cancer
Medical Xpress / Fatty food smells during pregnancy may raise obesity risk in offspring

A research team at the Max Planck Institute for Metabolism Research has found that the smell of fatty foods during pregnancy increases the risk of overweight and obesity in children. The researchers fed pregnant mice a healthy ...

23 hours ago in Pediatrics
Medical Xpress / Study investigates treatment safety in cases of late HIV diagnosis

About 40 million people worldwide are living with HIV infection. In the United Kingdom, there are approximately 100,000 people affected. If the infection is not treated, the body will eventually be unable to defend itself ...

22 hours ago in HIV & AIDS
Phys.org / What happens to creams and drugs in space? Behavior of soft matter in weightlessness studied

The shelf life of a sunscreen, the stability of mayonnaise, the effectiveness of a drug; these all depend on what is happening within the materials that make up gels or glasses, disordered structures that change slowly over ...

9 hours ago in Astronomy & Space
Medical Xpress / Stem cell organoids mimic aspects of early limb development

Scientists at EPFL have created a scalable 3D organoid model that captures key features of early limb development, revealing how a specialized signaling center shapes both cell identity and tissue organization.

22 hours ago in Medical research
Phys.org / How deforestation turbocharged Indonesia's deadly floods

The deadly flooding that has killed hundreds in Indonesia was largely the result of monsoon rains and a rare tropical storm. But something else may have played a role: deforestation.

9 hours ago in Earth
Medical Xpress / FDA pulls plan to require asbestos testing in talc-based cosmetics

Talc-based makeup and powders will not go through new asbestos testing requirements after the U.S. Food and Drug Administration (FDA) chose to pull back a proposed rule last week.

16 hours ago in Health
Phys.org / VIRE: A global data platform to better understand viruses

Researchers have developed VIRE, a database that integrates approximately 1.7 million viral genomes derived from more than 100,000 metagenomes worldwide. Metagenomic data is obtained by comprehensively sequencing all DNA ...

16 hours ago in Biology
Phys.org / Flood disaster prediction using multi-scale deep learning and neuro-fuzzy inference

A new algorithmic framework that can predict flooding could help save lives and reduce the devastation as climate change drives more intense and unpredictable rainfall.

16 hours ago in Earth
Phys.org / Why being single might feel empowering as a woman in your 20s, but not your 30s

If you're a woman in your 20s, being single may feel like an empowering lifestyle choice. Taking smug delight in the recent Vogue article, Is Having A Boyfriend Embarrassing Now?, you can rest assured that you're independent, ...

18 hours ago in Other Sciences