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Medical Xpress / In vivo CRISPR screen identifies gene edits that strengthen CAR-T therapy against solid tumors
For patients with blood cancers like leukemia and lymphoma, the immunotherapy known as CAR-T cell therapy can be lifesaving. Doctors remove a patient's immune cells, called T cells, engineer them in the lab to better recognize ...
Phys.org / Severe weather now a key predictor of where bird species occur in North America
Scorching heat waves, severe cold snaps and other extreme weather events are limiting where species can exist—and affecting biodiversity estimates—for more than 500 North American bird species, according to a new, Yale–led ...
Medical Xpress / Long before adulthood, a chemical mark may quietly shape how the brain handles stress
Stress or trauma during childhood may leave people more vulnerable to mental health struggles and stress later in life. Scientists think one reason could be that early-life stress leaves lasting molecular bookmarks on DNA, ...
Medical Xpress / Prostate cancer prognosis linked to prostate-specific antigen levels below threshold
After treatment for metastatic prostate cancer, a drop in prostate-specific antigen (PSA) levels in the blood is an indicator that treatment is working. A recent real-world study indicates that reaching a PSA level below ...
Phys.org / Unsupervised free time increases the likelihood that adolescents will engage in violent behavior, 21-country study finds
A study involving more than 58,000 adolescents from 21 countries found that "unstructured free time"—defined as periods without adult supervision or activities guided by educational, cultural or athletic goals—is strongly ...
Medical Xpress / Silent Strep A infections may explain immunity gained by adulthood
Exposure to Streptococcus pyogenes (Strep A) that causes mild or no symptoms can trigger the body's immune response and naturally build protection, potentially solving a nearly 100-year-old mystery of immunity.
Phys.org / Scholar's work in South America helps fight Chagas disease in the U.S.
A three-month Fulbright U.S. Scholar trip to Argentina wasn't just about bringing Texas know-how to South America for Gabriel Hamer, Ph.D., a Texas A&M AgriLife Research entomologist and professor in the Department of Entomology ...
Medical Xpress / Researchers identify possible marker of suicidal thoughts
Researchers at the Netherlands Institute for Neuroscience have identified a possible biological marker linked to severe suicidal thoughts. The finding, published in The British Journal of Psychiatry, may also help explain ...
Phys.org / Sugar molecule could help protect against dangerous hospital fungus Candida auris
Researchers have developed a potential new approach against the highly drug-resistant hospital fungus Candida auris. They discovered that a synthetic sugar molecule that is a natural part of the fungus's cell wall, but is ...
Phys.org / Late Paleozoic Ice Age warming event hints at potential climate 'tipping point'
Researchers say a spike in temperatures during an ice age 304 million years ago could inform what climate scientists are learning about rapidly changing conditions today.
Phys.org / Drug-carrying nanoparticles shrink venous malformations by 70% in mice
Venous malformations are abnormally shaped veins that develop when the cells lining blood vessels grow too fast when they aren't supposed to. Children can be born with them, and as the child grows, the venous malformations ...
Phys.org / Europe's worst medieval flood highlights risk of successive extreme events
New research involving the University of Liverpool has provided comprehensive insights into the largest flood event in Europe over the past millennium—the flood traditionally known as "St. Mary Magdalene's Flood" of 1342.