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Medical Xpress / Deep learning model predicts how individual cells influence disease outcomes
A computational method called scSurv, developed by researchers at Institute of Science Tokyo, links individual cells to patient outcomes using widely available bulk RNA sequencing data. The approach uses single-cell reference ...
Phys.org / Clearing circular RNA from cells extends lifespan, C. elegans study reveals
Cells in our bodies produce RNA based on genetic information stored in DNA, and RNA serves as a blueprint for making proteins. Researchers at KAIST have discovered a new phenomenon: Removing "circular RNA" that accumulates ...
Phys.org / An AI-guided gene-editing tool for more precise and safer DNA correction
Researchers at the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine) have developed a revolutionary new method to improve compact gene-editing tools known as base editors, which enable smaller, ...
Medical Xpress / Home-based chemotherapy: Pilot study demonstrates safety and feasibility
In a study published in NEJM Catalyst, Mayo Clinic researchers demonstrate that chemotherapy can be safely delivered in patients' homes. The study evaluated Mayo Clinic's Cancer CARE Beyond Walls (Connected Access and Remote ...
Medical Xpress / The Alzheimer's gut-brain link: How butyrate could curb amyloid-β buildup and inflammation
Alzheimer's disease (AD) is a neurodegenerative disease that causes progressive memory loss and a significant decline in mental functions. Past studies have shown that people with AD exhibit a buildup of a protein called ...
Phys.org / Monte Verde fieldwork resets age of famous South American archaeological site
New research led by a University of Wyoming archaeologist near an ancient encampment in South America challenges a relatively new but widely accepted theory that the people who made and used Clovis points in North America ...
Medical Xpress / How an imbalanced gut microbiome worsens chronic kidney disease
Researchers at UC Davis School of Medicine have uncovered how an imbalanced gut microbiome escalates the production of metabolic byproducts by certain gut bacteria. This imbalance drives a feedback loop that worsens chronic ...
Medical Xpress / Babies learn a lot in their first year. But their behavior doesn't always tell the full story
Anyone who has spent time with a baby knows how unpredictable the first year can feel. One week a baby suddenly seems to "get" something new. The next week, that same response may disappear.
Phys.org / Most mass spectrometers can process just a few molecules at once: Reengineered prototype does a billion simultaneously
Mass spectrometry is already a powerful tool for determining what kind and how many molecules are present in a given sample. But most instruments still analyze their molecules one or just a few at a time, an approach that ...
Phys.org / ISS study identifies thresholds for muscle atrophy and fiber changes in reduced gravity
It's well known that spaceflight causes muscle atrophy and other biological changes in reduced gravity, and especially in near-zero gravity (microgravity) environments. However, the gravity threshold needed to maintain sufficient ...
Medical Xpress / From pathology image to biological discovery: LazySlide uses foundation models to connect tissue images and RNA data
Microscopic images of human tissue are a cornerstone of biomedical research and clinical diagnostics. Yet despite their importance, these images often remain difficult to analyze systematically and to connect with other types ...
Phys.org / How our planet's history was shaped when the Earth moved
The history of Earth is written on the great tablets of tectonic plates. The motions of plates shaped land masses, formed oceans, and created the varied climates and habitats that set the stage for evolution and the diversity ...
