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Medical Xpress / Small number of 'highly plastic' cancer cells drive disease progression and treatment resistance
A small number of cancer cells with the ability to change their identities and behaviors appear to be a key driver of cancer progression and its ability to evolve resistance to treatment.
Medical Xpress / Manipulating blood CO₂ levels may help clear toxic proteins from the brain
Abnormal clumps of proteins like α-synuclein, amyloid beta and tau are associated with neurodegenerative conditions like Parkinson's and Alzheimer's disease, but a waste removal mechanism called the glymphatic pathway can ...
Medical Xpress / Carbon-ion therapy offers nonsurgical option for early breast cancer treatment
For many women with early breast cancer, surgery is effective but life-altering. New five-year data from the National Institutes for Quantum Science and Technology (QST) suggest that a precisely targeted, high-energy particle ...
Phys.org / Physicists bridge worlds of quantum matter
A new unified theory connects two fundamental domains of modern quantum physics: It joins two opposite views of how a single exotic particle behaves in a many-body system, namely as a mobile or static impurity among a large ...
Phys.org / First direct evidence of Migdal effect opens new path for dark matter search
In a landmark discovery that bridges nearly a century of theoretical physics, a Chinese research team has successfully captured the first direct evidence of the Migdal effect, a breakthrough with profound implications for ...
Phys.org / New method creates acinar cells involved in formation of pancreatic cancer
Organoids are three-dimensional miniature models of organs, grown in a dish. They have become a valuable tool for studying human development, organ regeneration, function, and disease progression. Organoids derived from patient ...
Medical Xpress / Progression-free survival prolonged with sacituzumab govitecan plus pembrolizumab in triple-negative breast cancer
For patients with previously untreated, programmed death ligand 1 (PD-L1)-positive, locally advanced unresectable or metastatic triple-negative breast cancer (TNBC), sacituzumab govitecan plus pembrolizumab yields significantly ...
Phys.org / New analysis disputes historic earthquake, tsunami and death toll on Greek island
For decades, researchers thought that an October 1843 earthquake on the small Greek island of Chalke caused a powerful tsunami and led to the deaths of as many as 600 people. But a new analysis of primary accounts of the ...
Medical Xpress / Childhood ADHD linked to midlife physical health problems
People who have ADHD traits at age 10 are more likely than those without such traits to have physical health problems and to report physical health-related disability at age 46, according to a study led by University College ...
Phys.org / Calm seas can drive coral bleaching, research reveals
New research by Monash University and the ARC Center of Excellence for the Weather of the 21st Century analyzed close to three decades of weather data during the coral bleaching season and identified the prevalence of "doldrum ...
Medical Xpress / Tumor cells steal immune mitochondria to aid lymph node spread
Stanford University-led researchers report that tumor cells hijack mitochondria from immune cells, reducing anti-tumor immune function and activating cGAS-STING and type I interferon signaling that promotes lymph node metastasis.
Phys.org / How early cell membranes may have shaped the origins of life
Modern cells are complex chemical entities with cytoskeletons, finely regulated internal and external molecules, and genetic material that determines nearly every aspect of their functioning. This complexity allows cells ...