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Phys.org / Location matters: How one fat molecule can help trigger both cell limbo and cell death
When cells experience enough chronic stress, they can stop dividing permanently. In this state of cellular limbo, known as replicative senescence, cells remain alive but no longer proliferate. Pinpointing the stressors that ...
Tech Xplore / Exploring AI's growing role in scientific peer review
James Zou is a computer scientist at Stanford University who has been exploring how large language models (LLMs) can assist scientific peer review—and more broadly, how AI agents might accelerate research. It is a provocative ...
Medical Xpress / A 'breathing' lung organoid enables measurement of lung stiffness
Researchers at the Institute of Industrial Science, the University of Tokyo, have developed a system that allows human lung organoids to expand in a breathing-like manner by applying pressure from inside the tissue. The platform ...
Phys.org / No dyes, less cell stress: How mid-infrared ultrasound imaging tracks lipids live
A team at Helmholtz Munich and the Technical University of Munich (TUM) has developed a new microscopy technique that can distinguish lipid species in living cells—in particular cholesterol and sphingomyelin—and map them ...
Phys.org / Binding to RNA is not enough—changing its shape is what makes a drug work, study reveals
Ribonucleic acids (RNAs) serve as messengers between DNA and protein production, and perform a wide variety of regulatory functions across different cellular processes. This makes them an interesting target for drug designers. ...
Medical Xpress / Shedding light on the brain: New method controls neural pathway communication
Understanding how the brain works requires more than studying single regions in isolation. The cerebral cortex depends on long-distance connections that link specialized areas into coordinated networks. But scientists have ...
Medical Xpress / Researchers investigate the Planetary Health Diet in pregnancy
Following The Planetary Health Diet in pregnancy can meet key nutrient requirements, suggesting that women who eat more sustainably in pregnancy may have higher intakes of several key pregnancy-related nutrients, including ...
Medical Xpress / Unraveling the neural circuitry that makes mice attack
When defending their territory, male mice typically appear threatening before launching an attack, ensuring that aggression does not unnecessarily escalate. Researchers at the University of Tsukuba found that increased activity ...
Medical Xpress / Prioritizing potentially cancer-causing mutations in real-world cancer genomics
Hiroshima University researchers have developed a practical framework to identify candidate pathogenic variants hidden among the large number of variants of uncertain significance (VUS) detected in comprehensive genomic profiling ...
Medical Xpress / Hospitals are failing to identify malnutrition
Malnutrition not only negatively impacts health, but also causes poor healing and increased infection risks, lengthening hospital stays and further burdening an under-resourced system. One in three hospital patients are not ...
Phys.org / Into the fungal unknown: New tool maps fungal gene functions without reference genomes
While RNA sequencing (RNA-seq) has become a standard tool for profiling which genes are active in an organism, determining the actual biological functions of those genes in fungi remains a significant technical challenge. ...
Medical Xpress / A long-term and scalable system to record from neural organoids
Neural organoids have been heralded as having huge potential for advancing our knowledge of the brain in several fields. These include exploring the responses of brain tissue to drugs, investigating the effect of specific ...