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Phys.org / Receptor with 'rubber band' paves way for new pain and cancer drugs
The human P2X4 receptor plays an important role in chronic pain, inflammation and some types of cancer. Researchers at the University of Bonn and the University Hospital Bonn (UKB) have now discovered a mechanism that can ...
Phys.org / Evidence of rain-driven climate on Mars found in bleached rocks scattered in Jezero crater
Rocks that stood out as light-colored dots on the reddish-orange surface of Mars now are the latest evidence that areas of the small planet may have once supported wet oases with humid climates and heavy rainfall comparable ...
Phys.org / New molecular view of cholera 'tail' could inform better treatment
Cholera is a deadly bacterial disease that kills about 95,000 people every year. Vibrio cholerae bacteria infect cells in the small intestine, which the bacteria can do in part due to their flagella—powerful tail-like structures ...
Medical Xpress / Molecular switch links early-life stimulation to lasting memory changes
Researchers have identified a molecular mechanism that helps explain why growing up in a stimulating environment enhances memory. In contrast, a lack of stimulation can impair it. The team from the Institute for Neurosciences ...
Phys.org / Deciphering the heavyweights of the tetraquark world
The CMS collaboration reports the first measurement of the quantum properties of a family of tetraquarks that was recently discovered at the LHC.
Phys.org / Seeing inside smart gels: Scientists capture dynamic behavior under stress
Advances in materials science have led to the development of "smart materials," whose properties do not remain static but change in response to external stimuli. One such material is poly(N-isopropylacrylamide), or PNIPAM, ...
Phys.org / Shapeshifting gates guard the cell nucleus, challenging old ideas
An international study led by the University of Basel has discovered that nuclear pore complexes—tiny gateways in the nuclear membrane—are not rigid or gel-like as once thought. Their interiors are dynamically organized, ...
Medical Xpress / Backup DNA repair system could be cancer's weak spot
The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break—when both sides of the DNA helix are cut at once. Healthy cells can normally fix these breaks using highly ...
Medical Xpress / KRAS-mutant cancers: Potential target could overcome treatment resistance
Researchers at The University of Texas MD Anderson Cancer Center have identified a specific protein, RASH3D19, that is responsible for activation of RAS signaling pathways involved in aggressive tumor growth and resistance ...
Phys.org / Common aldehydes transformed by light could accelerate drug discovery and material development
A new chemical method that could speed up the creation of medicines, materials and products people rely on every day has been developed by University of Hawaiʻi at Mānoa Department of Chemistry researchers. The work, published ...
Phys.org / New levitating sensors could pave way to dark matter detection and quantum sensing
A new type of sensor that levitates dozens of glass microparticles could revolutionize the accuracy and efficiency of sensing, laying the foundation for better autonomous vehicles, navigation and even the detection of dark ...
Phys.org / C-Compass: AI-based software maps proteins and lipids within cells
A new tool developed by Helmholtz Munich and the German Center for Diabetes Research and the University of Bonn makes spatial proteomics and lipidomics easier to use—no coding required. C-COMPASS allows scientists to profile ...