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Tech Xplore / New receiver frontend system achieves 108 Gb/s data rate using PAM-8 signals
High-voltage, higher-order PAM-8 signals are essential to achieve data rates beyond 100 Gb/s, requiring highly linear receivers to maintain excellent signal-to-noise ratios.
Medical Xpress / Sequencing method can analyze millions of T cells at a fraction of the cost
Studying T cells, the immune cells most responsible for responding to infections and cancers, just received a significant boost in the form of a new technique from St. Jude Children's Research Hospital. While T-cell analysis ...
Medical Xpress / Many men may not need long-term hormone therapy for prostate cancer, study suggests
A study co-led by investigators at the UCLA Health Jonsson Comprehensive Cancer Center found that most of the benefits of androgen deprivation therapy (ADT) for prostate cancer occur within the first 9 to 12 months. Extending ...
Medical Xpress / AI learns from the tree of life to support rare disease diagnosis
Researchers have created an artificial intelligence model that can identify which mutations in human proteins are most likely to cause disease, even when those mutations have never been seen before in any person.
Medical Xpress / Epigenetic changes regulate gene expression, but what regulates epigenetics?
All the cells in an organism have the exact same genetic sequence. What differs across cell types is their epigenetics—meticulously placed chemical tags that influence which genes are expressed in each cell. Mistakes or ...
Phys.org / How cancer cells tolerate missing chromosomes
A hallmark of cancerous cells is an abnormal number of chromosomes or chromosome arms, known as aneuploidy. While aneuploidy is detrimental to regular cells, it occurs in as many as 90% of tumors. How cancer cells tolerate ...
Tech Xplore / Student maps where cyclists really go—and why it matters for city planning
A study co-authored by UBC Okanagan Associate Professor Dr. Mahmudur Fatmi and doctoral student Bijoy Saha uses Okanagan travel-diary data to model destination choices across full bike "tours."
Medical Xpress / Five key blood proteins may reveal hidden danger of early death
Elevated levels of five proteins in our blood can help predict risk of mortality, a new study from the University of Surrey finds. Scientists believe the proteins (PLAUR, SERPINA3, CRIM1, DDR1 and LTBP2), that play key roles ...
Medical Xpress / HER2-targeted therapy shows promising results in rare bile duct cancers
Zanidatamab, a bispecific HER2-targeted antibody, delivered clinically meaningful and durable responses for patients with HER2-positive biliary tract cancer (BTC), according to final results from the HERIZON-BTC-01 clinical ...
Phys.org / Gelada baboons fake fertility to protect their young from infanticide when new males take over
In nature, it is not usual for animals to be deceptive, as evolution has typically favored communication that benefits both the sender and receiver by conveying reliable information. But, there are exceptions, particularly ...
Phys.org / Tiny copepod reveals that gene location influences natural selection
A new study by researchers at the University of Wisconsin–Madison provides the first empirical evidence connecting the chromosomal location of genes to natural selection, indicating the arrangement of genes can influence ...
Phys.org / Nanowire platform reveals elusive astrocytes in their natural state
Scientists have engineered a nanowire platform that mimics brain tissue to study astrocytes, the star-shaped cells critical for brain health, for the first time in their natural state.