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Phys.org / From inhibition to destruction: Kinase drugs found to trigger protein degradation
Protein kinases are the molecular switches of the cell. They control growth, division, communication, and survival by attaching phosphate groups to other proteins. When these switches are stuck in the "on" position, they ...
Medical Xpress / How a mitochondrial mutation rewires immune function
Scientists have discovered how a mitochondrial mutation rewires immune function in a model of inherited primary mitochondrial disorders, which often lead to severe disability and death. They have discovered that this single ...
Phys.org / Boiling oceans may lurk beneath the ice of solar system's smallest moons
The outer planets of the solar system are swarmed by ice-wrapped moons. Some of these, such as Saturn's moon Enceladus, are known to have oceans of liquid water between the ice shell and the rocky core and could be the best ...
Medical Xpress / High risk of metastatic recurrence found among young cancer patients
A new study of adolescents and young adults (AYAs) with seven common cancers reveals that nearly one in ten patients diagnosed with non-metastatic disease later develop metastatic recurrence—a condition associated with ...
Medical Xpress / A rare respiratory disease may be more prevalent in Quebec
A study led by the Research Institute of the McGill University Health Center (The Institute) has identified a rare genetic variant in the ODAD4 gene that causes primary ciliary dyskinesia (PCD), a chronic hereditary disorder ...
Tech Xplore / Low-cost green hydrogen: New electrode design dramatically reduces wear in membrane electrolyzers
A University of California, Berkeley chemist has engineered a new technology that could make hydrogen-producing fuel cells last longer and hasten the arrival of cost-competitive, eco-friendly versions of the fuel source.
Tech Xplore / More efficient aircraft engines: Scientists reveal optimization potential
With its "Flightpath 2050" strategy, the European Commission has outlined a framework for the aviation industry that aims to reduce emissions as well as fuel and energy consumption. Among other things, this requires more ...
Medical Xpress / Potential new second-line option for advanced biliary tract cancer identified
Biliary tract cancers, including intrahepatic, perihilar, and extrahepatic cholangiocarcinoma and gallbladder cancer, are among the most aggressive gastrointestinal malignancies. Treatment options remain limited once the ...
Tech Xplore / The Hong Kong high-rise fire shows how difficult it is to evacuate in an emergency
The Hong Kong high-rise fire, which spread across multiple buildings in a large residential complex, has killed dozens, with hundreds reported missing.
Medical Xpress / Social support predicts longevity and improved quality of life among older adults
Two recent studies from the University of Eastern Finland show that social support plays an important role in health and well-being in later life. Having access to adequate social support is associated with longevity among ...
Phys.org / Bilingual brains switch modes as Czech speakers process English like natives, even when it means making 'native' mistake
A new study shows that while Czech speakers are immune to specific grammar illusions in their mother tongue, they unconsciously adopt the "glitchy" processing patterns of native speakers when reading in English.
Tech Xplore / Tech firms from Dell to HP warn of memory chip squeeze from AI
Dell Technologies Inc., HP Inc. and other tech companies are warning of potential memory-chip supply shortages in the coming year due to soaring demand from the build-out of artificial intelligence infrastructure.