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Phys.org / Decoding the chemistry of life: Maximum entropy reveals how mutations alter enzymes and drive drug resistance
For decades, Arieh Warshel, USC Distinguished Professor of Chemistry and a 2013 Nobel laureate, has used computer simulations to understand how enzymes—fundamental to nearly every biological process in living organisms—carry ...
Medical Xpress / Octopus-inspired 3D micro-LEDs pave the way for selective pancreatic cancer therapy
Conventional pancreatic cancer treatments face a critical hurdle due to the dense tumor microenvironment (TME). This biological barrier surrounds the tumor, severely limiting the infiltration of chemotherapy agents and immune ...
Medical Xpress / Pain misconceptions push 1 in 4 people toward spinal surgery
If you live with constant lower back pain, surgery can start to look like the only way out. Yet new research from the University of South Australia published in the Australian Health Review shows that it's mindset, more than ...
Medical Xpress / 'Are you married?' Why doctors ask invasive questions during treatment
It's a rare occasion when my worlds of biomedical informatics and serialized lesbian melodrama fandom collide.
Medical Xpress / Research strengthens evidence linking alcohol use to cancer
As Americans gear up for the holiday season, new research offers a timely reminder to reflect on the long-term health effects of raising a celebratory glass—or two. Alcohol is known to increase the risk of several cancers ...
Phys.org / Limitations of AI-based material prediction: Crystallographic disorder represents a stumbling block
Computer simulations and artificial intelligence often make significant errors when predicting the properties of new, high-performance materials, according to a new international study led by the University of Bayreuth. In ...
Medical Xpress / Dietary restriction fuels T cells with ketones, boosting their cancer-fighting stamina
Reducing calorie intake helps cancer-fighting immune cells do their jobs more effectively, reports a study by Van Andel Institute scientists and collaborators. The findings lay the groundwork for developing dietary strategies ...
Phys.org / Archaeologists use lasers to locate ancient settlements and artifacts on Greek Islands
A group of scientists are studying the Cyclades, an island group in Greece's Aegean Sea, looking for signs of early human activity. They are using technology such as laser scanning and magnetometry, which may be more effective ...
Phys.org / Long-term study of nearby blazar reveals complex emission patterns
Using NASA's Swift and Fermi space telescopes, Indian astronomers have conducted a long-term multiwavelength study of a nearby blazar designated TXS 0518+211. Results of the study, published Nov. 26 on the arXiv pre-print ...
Phys.org / Warmer seas and heavier rains linked to deadly Asia flooding, study finds
Warmer seas and heavier rains linked to climate change, along with Indonesia and Sri Lanka's unique geographies and vulnerabilities, combined to produce deadly flooding that killed hundreds, scientists said Thursday.
Medical Xpress / Preoperative radiation may improve antitumor immune response in most common form of breast cancer
Preoperative radiation improved T-cell infiltration (TCI) in patients with hormone receptor (HR)-positive, HER2-negative breast cancer when administered in combination with pembrolizumab (Keytruda) and chemotherapy and led ...
Medical Xpress / Sentinel lymph node biopsy may be safely omitted in some patients with early-stage breast cancer: Phase III trial
Skipping sentinel lymph node biopsy (SLNB) in patients with clinically node-negative, hormonal receptor (HR)-positive, HER2-negative early-stage breast cancer did not compromise regional control or survival after a median ...
