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Medical Xpress / Next-generation HIF-2α inhibitor shows promise in kidney cancer translational clinical trial
The first-in-patient, single-arm ARC-20 clinical trial, led by Dana-Farber Cancer Institute's Toni K. Choueiri, MD, has evaluated casdatifan, a next-generation HIF-2α inhibitor, as monotherapy for metastatic clear cell renal ...
Medical Xpress / Lived experience is often dismissed—but we should recognize it as a form of expertise
Institutions increasingly invite people to contribute their lived experience. Government agencies appoint patients to advisory panels and call on communities for their views on policy. Health New Zealand employs peer support ...
Medical Xpress / NHS patients are being socially prescribed yoga—but is yoga ready to help them?
Yoga can be seen as an accessible way to exercise and improve well-being. You don't always need a gym membership, specialist machinery or other people to do it.
Tech Xplore / Australian musicians hate AI using their songs, but have little legal protection
Music from Kylie Minogue, John Farnham, INXS, Midnight Oil, AC/DC, Tones and I, Gotye, Ben Frost, Nick Cave, Tame Impala, Parkway Drive, The Living End and Vance Joy has been found in a database of 12 million songs used to ...
Phys.org / Ozone depletion began decades before discovery of ozone hole, scientists find
The Antarctic ozone hole was discovered in 1985, when scientists observed a severe depletion in Earth's protective layer of stratospheric ozone. Industrial chemicals known as chlorofluorocarbons (CFCs), then widely used as ...
Phys.org / Perfluorooctanoic acid in the Seto Inland Sea: Variability, transport, and fate
Perfluorooctanoic acid (PFOA) is one of the per- and polyfluoroalkyl substances (PFAS), a class of substances within a broader universe of organofluorine compounds. PFOA has potential adverse effects on human health and environmental ...
Medical Xpress / Alzheimer's biomarkers may forecast dementia progression in people 80 and older
Cognitive decline in very old adults has been considered for decades to be an almost inevitable consequence of aging. In clinical practice, this has contributed to many memory problems in patients over age 80 being interpreted ...
Phys.org / Deep inside crocodile skulls, 100 million years of brain evolution barely registers
Although modern crocodiles, alligators, caimans and gharials are restricted to the tropics, their fossil record tells a very different story. Ancient crocodylians once inhabited much of the globe and exhibited a remarkable ...
Medical Xpress / Uncovering gene-based clues to how disrupted healing in stomach cells increases cancer risk
Few areas of the body face more daily stress and potential damage than the stomach, which must manage everything we swallow. Along with this constant strain, the stomach also produces acid that can damage its own lining and ...
Tech Xplore / Chevrolet Bolt vs. Nissan Leaf, a $30,000 EV comparison
Many new electric vehicles are prohibitively expensive for car shoppers. But there are a few relatively low-cost options that provide plenty of usable range and utility. One great example is the Nissan Leaf. Originally debuting ...
Phys.org / Ultraluminous X-ray source in Whale galaxy investigated for spectral and timing variability
Astronomers from Germany and Turkey have analyzed available data from various space telescopes to investigate an ultraluminous X-ray source designated X-4, which is located in the nearby galaxy NGC 4631. Results of the new ...
Tech Xplore / Swedish court orders Google pay nearly $2 bn for favoring its price comparisons
A Swedish market court on Wednesday ordered Google to pay some 14.3 billion kronor ($1.46 billion) in damages, plus interest, to price comparison site Pricerunner for promoting its own shopping comparisons in search results.
