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Nitazenes—a class of highly potent synthetic opioids—are rapidly emerging as a major contributor to the overdose crisis, according to a Pain Medicine review published today by authors from Vanderbilt University Medical ...

Scientists from the laboratory of Dr. Tomáš Pluskal at IOCB Prague are helping colleagues around the world identify previously unknown compounds. They have created an extensive library called MSnLib, which contains several ...

Using the James Webb Space Telescope (JWST), astronomers have detected what appears to be a faint and small star-forming complex. The discovery of the new complex, which received the designation LAP2, is detailed in a research ...

How do cells know what they should become as the body develops? Biological development depends crucially on spatial patterns: the lines that eventually give rise to segments, organs, or markings like stripes and spots. Yet ...

Children who are expelled from preschool are subsequently more likely to experience academic failure and enter what scientists and advocates call the "cradle-to-prison pipeline," meaning that these children tend to follow ...

In almost all solid tumors—i.e. cancers with a solid tissue structure—the detection of tumor cells in the lymph nodes is considered a decisive marker for the progression of the disease. Lymph node involvement has a significant ...

In 2022–2023, a wall mural depicting a procession of priests walking toward a stationary fire altar was recovered at the Royal Palace at Sanjar-Shar.

A pharmaceutical scientist at the National University of Singapore (NUS) has developed a method that can measure the kinetic efficiency of an enzyme against more than 200,000 potential peptide substrates in a single experiment.

Alzheimer's disease (AD) is a neurodegenerative condition that typically affects older people and is the leading cause of dementia worldwide. AD is characterized by progressive cognitive impairment caused by a decades-long ...

A new study led by the U.S. Forest Service, with Chapman University as a key senior collaborator, published in Nature Communications, suggests Earth's own tropical soils may contribute to climate change as global warming ...

Scientists have uncovered how lymphatic vessels—the kidney's "plumbing system"—undergo dramatic changes during chronic transplant rejection, becoming structurally disorganized and spreading to unusual parts of the kidney.

A study examining the effects of higher temperatures on soil shows that warming alone does not increase levels of carbon dioxide emitted from the soil. Instead, higher temperatures combined with more added carbon—and more ...