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Medical Xpress / Next-generation HIF-2α inhibitor shows promise in kidney cancer translational clinical trial
The first-in-patient, single-arm ARC-20 clinical trial, led by Dana-Farber Cancer Institute's Toni K. Choueiri, MD, has evaluated casdatifan, a next-generation HIF-2α inhibitor, as monotherapy for metastatic clear cell renal ...
Phys.org / What made trees possible? New research points to drought
A study is reframing a fundamental question in plant evolution: What made trees possible? Researchers from Cal Poly Humboldt, Yale University, the University of Hohenheim in Germany and the Czech Academy of Sciences set out ...
Medical Xpress / Your dominant hand is made, not born, experiments suggest
Most people favor one hand, and that hand tends to be the better one for writing, throwing and managing chopsticks. The long-standing view is that the dominant hand is "born" more capable, its skills rooted in a brain hemisphere ...
Phys.org / 3,000-year-old Irish Bronze Age site may be one of Europe's earliest 'town-like' settlements
A major prehistoric center in Ireland was among the first large, organized settlements to develop in Western Europe more than 3,000 years ago, new research reveals. The study, published today in Antiquity, identifies Haughey's ...
Medical Xpress / Genetic differences affecting toddler activity levels are also associated with ADHD
A toddler's activity levels are influenced by genetic differences, with some of the same genetic markers also linked to attention-deficit/hyperactivity disorder (ADHD), according to new research from the University of Surrey. ...
Medical Xpress / Bacteria's 'mix-and-match' code could create new cancer-fighting drugs
A team of researchers at the University of Warwick and Monash University has solved a puzzle that has stumped drug developers for decades: how bacteria naturally create multiple versions of powerful cancer therapies. The ...
Medical Xpress / COVID-19 vaccine boosters may help protect against future animal coronaviruses, research suggests
COVID-19 vaccine boosters not only protect against SARS-CoV-2—the virus behind the most recent pandemic—but may also help protect against some future coronaviruses that risk spreading from animals to humans, Cambridge researchers ...
Phys.org / Polymer network reconfigures in sequence, helping elastomers stay tough under strain
Shock-absorbing sneaker soles are likely made of polyurethane, a highly elastic and tough polymer. The ability of these elastomers to absorb impact without breaking is extremely important for practical applications. While ...
Medical Xpress / How athletes envision the future of sport during climate change
There is an urgent need for greater climate action across the sports industry, emphasizing the critical role athletes can play in shaping a more sustainable future for sport, according to a new briefing report.
Tech Xplore / Plane battery fire tests back 100 Wh limit for carry-on devices
Lithium-ion batteries in personal electronic devices (PEDs) such as laptops, smartphones, powerbanks and electronic cigarettes can pose a serious safety risk in air travel. Damaged or overheated batteries can combust or explode. ...
Phys.org / Perfluorooctanoic acid in the Seto Inland Sea: Variability, transport, and fate
Perfluorooctanoic acid (PFOA) is one of the per- and polyfluoroalkyl substances (PFAS), a class of substances within a broader universe of organofluorine compounds. PFOA has potential adverse effects on human health and environmental ...
Phys.org / NASA rolls out three robotic moon missions as 2029 lunar base plans take shape
NASA on Tuesday announced new uncrewed missions to aid in the future creation of a lunar surface base, a project beginning to take shape despite recent setbacks.